Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/14949 |
Resumo: | Universidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil. |
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Urzêda, Márcio A.Marcussi, SilvanaPereira, Luciana L. SilvaFrança, Suzelei C.Pereira, Ana Maria S.Pereira, Paulo S.Silva, Saulo L. daGuimarães, César L. S.Calderon, Leonardo A.Stábeli, Rodrigo G.Soares, Andreimar M.Couto, Lucélio B.2016-07-14T15:27:51Z2016-07-15T18:40:39Z2016-07-14T15:27:51Z2016-07-15T18:40:39Z2013URZÊDA, Márcio A. et al. Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract. Evidence-Based Complementary and Alternative Medicine, v. 2013, p. 1-8, 2013.https://www.arca.fiocruz.br/handle/icict/1494910.1155/2013/191080engHindawiEvaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extractinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil.Universidade Federal de Lavras. Departamento de Química. Lavras, MG, Brasil.Universidade Federal de Lavras. Departamento de Química. Lavras, MG, Brasil.Universidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil.Universidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil.Universidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil.Universidade Federal de São João Del Rei. Campus Alto Paraopeba. Ouro Branco, MG, Brasil.Fundação Oswaldo Cruz. Centro de Estudos de Biomoléculas Aplicadas à Saúde. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz Rondônia. Porto Velho, RO, Brasil / Universidade Federal de Rondônia. Departamento de Medicina. Porto Velho, RO, Brasil / Instituto Brasileiro do Meio Ambiente e dos Recursos Naturais Renováveis. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Centro de Estudos de Biomoléculas Aplicadas à Saúde. Porto Velho, RO, Brasil/ Fundação Oswaldo Cruz Rondônia. Porto Velho, RO, Brasil / Universidade Federal de Rondônia. Departamento de Medicina. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Centro de Estudos de Biomoléculas Aplicadas à Saúde. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz Rondônia. Porto Velho, RO, Brasil / Universidade Federal de Rondônia. Departamento de Medicina. Porto Velho, RO, Brasil.Fundação Oswaldo Cruz. Centro de Estudos de Biomoléculas Aplicadas à Saúde. Porto Velho, RO, Brasil / Fundação Oswaldo Cruz Rondônia. Porto Velho, RO, Brasil / Universidade Federal de Rondônia. Departamento de Medicina. Porto Velho, RO, Brasil.Universidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil.The antihyperglycemic effects of several plant extracts and herbal formulations which are used as antidiabetic formulations have been described and confirmed to date. The main objective of this work was to evaluate the hypoglycemic activity of the aqueous extract of Anacardium humile. Although the treatment of diabetic animals with A. humile did not alter body weight significantly, a reduction of the other evaluated parameters was observed. Animals treated with A. humile did not show variation of insulin levels, possibly triggered by a mechanism of blood glucose reduction. Levels of ALT (alanine aminotransferase) decreased in treated animals, suggesting a protective effect on liver. Levels of cholesterol were also reduced, indicating the efficacy of the extract in reestablishing the balance of nutrients. Moreover, a kidney protection may have been achieved due to the partial reestablishment of blood glucose homeostasis, while no nephrotoxicity could be detected for A. humile. The obtained results demonstrate the effectiveness of A. humile extracts in the treatment of alloxan-induced diabetic rats. Therefore, A. humile aqueous extract, popularly known and used by diabetic patients, induced an improvement in the biochemical parameters evaluated during and following treatment of diabetic rats. Thus, a better characterization of the medicinal potential of this plant will be able to provide a better understanding of its mechanisms of action in these pathological processes.EvaluationHypoglycemicAnacardium humileAqueous Extractinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZTEXTEvaluation of the Hypoglycemic Properties.pdf.txtEvaluation of the Hypoglycemic Properties.pdf.txtExtracted texttext/plain39256https://www.arca.fiocruz.br/bitstream/icict/14949/4/Evaluation%20of%20the%20Hypoglycemic%20Properties.pdf.txt525a495d080a869a57c0d0a9cc39d7b4MD54ORIGINALEvaluation of the Hypoglycemic Properties.pdfapplication/pdf1659698https://www.arca.fiocruz.br/bitstream/icict/14949/2/Evaluation%20of%20the%20Hypoglycemic%20Properties.pdf2592361af83a329f2f954fe077444cb5MD52LICENSElicense.txttext/plain2991https://www.arca.fiocruz.br/bitstream/icict/14949/3/license.txt5a560609d32a3863062d77ff32785d58MD53icict/149492019-04-20 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| dc.title.pt_BR.fl_str_mv |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| title |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| spellingShingle |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract Urzêda, Márcio A. Evaluation Hypoglycemic Anacardium humile Aqueous Extract |
| title_short |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| title_full |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| title_fullStr |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| title_full_unstemmed |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| title_sort |
Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract |
| author |
Urzêda, Márcio A. |
| author_facet |
Urzêda, Márcio A. Marcussi, Silvana Pereira, Luciana L. Silva França, Suzelei C. Pereira, Ana Maria S. Pereira, Paulo S. Silva, Saulo L. da Guimarães, César L. S. Calderon, Leonardo A. Stábeli, Rodrigo G. Soares, Andreimar M. Couto, Lucélio B. |
| author_role |
author |
| author2 |
Marcussi, Silvana Pereira, Luciana L. Silva França, Suzelei C. Pereira, Ana Maria S. Pereira, Paulo S. Silva, Saulo L. da Guimarães, César L. S. Calderon, Leonardo A. Stábeli, Rodrigo G. Soares, Andreimar M. Couto, Lucélio B. |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Urzêda, Márcio A. Marcussi, Silvana Pereira, Luciana L. Silva França, Suzelei C. Pereira, Ana Maria S. Pereira, Paulo S. Silva, Saulo L. da Guimarães, César L. S. Calderon, Leonardo A. Stábeli, Rodrigo G. Soares, Andreimar M. Couto, Lucélio B. |
| dc.subject.en.eng.fl_str_mv |
Evaluation Hypoglycemic Anacardium humile Aqueous Extract |
| topic |
Evaluation Hypoglycemic Anacardium humile Aqueous Extract |
| description |
Universidade de Ribeirão Preto. Unidade de Biotecnologia. Ribeirão Preto, SP, Brasil. |
| publishDate |
2013 |
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2013 |
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2016-07-14T15:27:51Z 2016-07-15T18:40:39Z |
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2016-07-14T15:27:51Z 2016-07-15T18:40:39Z |
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URZÊDA, Márcio A. et al. Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract. Evidence-Based Complementary and Alternative Medicine, v. 2013, p. 1-8, 2013. |
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https://www.arca.fiocruz.br/handle/icict/14949 |
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10.1155/2013/191080 |
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URZÊDA, Márcio A. et al. Evaluation of the Hypoglycemic Properties of Anacardium humile Aqueous Extract. Evidence-Based Complementary and Alternative Medicine, v. 2013, p. 1-8, 2013. 10.1155/2013/191080 |
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