Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis

Detalhes bibliográficos
Autor(a) principal: Oliveira, Joanna R. Santos
Data de Publicação: 2011
Outros Autores: Regis, Eduardo G., Leal, Cássia R. B., Cunha, Rivaldo V., Bozza, Patrícia T., Cruz, Alda M. da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/25799
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil.
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spelling Oliveira, Joanna R. SantosRegis, Eduardo G.Leal, Cássia R. B.Cunha, Rivaldo V.Bozza, Patrícia T.Cruz, Alda M. da2018-04-12T13:23:54Z2018-04-12T13:23:54Z2011OLIVEIRA, Joanna R. Santos; et al. Evidence That Lipopolisaccharide May Contribute to the Cytokine Storm and Cellular Activation in Patients with Visceral Leishmaniasis. PLoS Negl Trop Dis., v.5, n.7, e1198, 10p, July 2011.1935-2727https://www.arca.fiocruz.br/handle/icict/2579910.1371/journal.pntd.00011981935-2735engPublic Library of ScienceLeishmaniose visceralCitocinasLipopolissacarídeoAtivação celularVisceral LeishmaniasisLipopolisaccharideCytokineCellular ActivationEvidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Universidade Federal do Mato Grosso do Sul. Departamento de Medicina Veterinária. Campo Grande, MS, Brasil.Universidade Federal do Mato Grosso do Sul. Departamento de Clínica Médica. Campo Grande, MS, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Plataforma Luminex. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil.Visceral leishmaniasis (VL) is characterized by parasite-specific immunosuppression besides an intense pro-inflammatory response. Lipopolisaccharide (LPS) has been implicated in the immune activation of T-cell deficient diseases such as HIV/AIDS and idiopathic lymphocytopenia. The source of LPS is gram-negative bacteria that enter the circulation because of immunological mucosal barrier breakdown. As gut parasitization also occurs in VL, it was hypothesized that LPS may be elevated in leishmaniasis, contributing to cell activation.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25799/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALjoaana_oliveira_etal_IO_2011.pdfjoaana_oliveira_etal_IO_2011.pdfapplication/pdf395068https://www.arca.fiocruz.br/bitstream/icict/25799/2/joaana_oliveira_etal_IO_2011.pdf73316fab713531fdf6c90ea29bc9ffc8MD52TEXTjoaana_oliveira_etal_IO_2011.pdf.txtjoaana_oliveira_etal_IO_2011.pdf.txtExtracted texttext/plain43991https://www.arca.fiocruz.br/bitstream/icict/25799/3/joaana_oliveira_etal_IO_2011.pdf.txt819cf4c02278bc49b0eb7ad146fac563MD53icict/257992022-06-24 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dc.title.pt_BR.fl_str_mv Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
title Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
spellingShingle Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
Oliveira, Joanna R. Santos
Leishmaniose visceral
Citocinas
Lipopolissacarídeo
Ativação celular
Visceral Leishmaniasis
Lipopolisaccharide
Cytokine
Cellular Activation
title_short Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
title_full Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
title_fullStr Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
title_full_unstemmed Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
title_sort Evidence that lipopolisaccharide may contribute to the cytokine storm and cellular activation in patients with visceral leishmaniasis
author Oliveira, Joanna R. Santos
author_facet Oliveira, Joanna R. Santos
Regis, Eduardo G.
Leal, Cássia R. B.
Cunha, Rivaldo V.
Bozza, Patrícia T.
Cruz, Alda M. da
author_role author
author2 Regis, Eduardo G.
Leal, Cássia R. B.
Cunha, Rivaldo V.
Bozza, Patrícia T.
Cruz, Alda M. da
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Joanna R. Santos
Regis, Eduardo G.
Leal, Cássia R. B.
Cunha, Rivaldo V.
Bozza, Patrícia T.
Cruz, Alda M. da
dc.subject.other.pt_BR.fl_str_mv Leishmaniose visceral
Citocinas
Lipopolissacarídeo
Ativação celular
topic Leishmaniose visceral
Citocinas
Lipopolissacarídeo
Ativação celular
Visceral Leishmaniasis
Lipopolisaccharide
Cytokine
Cellular Activation
dc.subject.en.pt_BR.fl_str_mv Visceral Leishmaniasis
Lipopolisaccharide
Cytokine
Cellular Activation
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ. Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2018-04-12T13:23:54Z
dc.date.available.fl_str_mv 2018-04-12T13:23:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, Joanna R. Santos; et al. Evidence That Lipopolisaccharide May Contribute to the Cytokine Storm and Cellular Activation in Patients with Visceral Leishmaniasis. PLoS Negl Trop Dis., v.5, n.7, e1198, 10p, July 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/25799
dc.identifier.issn.pt_BR.fl_str_mv 1935-2727
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0001198
dc.identifier.eissn.none.fl_str_mv 1935-2735
identifier_str_mv OLIVEIRA, Joanna R. Santos; et al. Evidence That Lipopolisaccharide May Contribute to the Cytokine Storm and Cellular Activation in Patients with Visceral Leishmaniasis. PLoS Negl Trop Dis., v.5, n.7, e1198, 10p, July 2011.
1935-2727
10.1371/journal.pntd.0001198
1935-2735
url https://www.arca.fiocruz.br/handle/icict/25799
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/25799/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/25799/2/joaana_oliveira_etal_IO_2011.pdf
https://www.arca.fiocruz.br/bitstream/icict/25799/3/joaana_oliveira_etal_IO_2011.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
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