Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi

Detalhes bibliográficos
Autor(a) principal: Reifur, Larissa
Data de Publicação: 2012
Outros Autores: Garcia-Silva, Maria Rosa, Poubel, Saloê Bispo, Alves, Lysangela Ronalte, Arauco, Paulo, Buiar, Diane Kelly, Goldenberg, Samuel, Cayota, Alfonso, Dallagiovanna, Bruno
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/39854
Resumo: Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. / Universidade Federal do Paraná. Setor de Ciências Biológicas. Departamento de Patologia Básica. Curitiba, PR, Brasil.
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spelling Reifur, LarissaGarcia-Silva, Maria RosaPoubel, Saloê BispoAlves, Lysangela RonalteArauco, PauloBuiar, Diane KellyGoldenberg, SamuelCayota, AlfonsoDallagiovanna, Bruno2020-02-11T15:01:02Z2020-02-11T15:01:02Z2012REIFUR, Larissa et al. Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.107, n. 6, p. 816–819, 2012.1678-8060https://www.arca.fiocruz.br/handle/icict/3985410.1590/s0074-027620120006000181678-8060porFundação Oswaldo Cruz. Instituto Oswaldo CruzTrypanosoma cruziTRNARNA, TransferRNA, UntranslatedStress, PhysiologicalMolecular StructureARN de TransferenciaARN no TraducidoEstrés FisiológicoEstructura MolecularRNA de TransferênciaRNA não TraduzidoEstresse FisiológicoEstrutura MolecularDistinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruziinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. / Universidade Federal do Paraná. Setor de Ciências Biológicas. Departamento de Patologia Básica. Curitiba, PR, Brasil.Institut Pasteur de Montevideo. Functional Genomics Unit. Mataojo, Montevideo, Uruguay.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Universidade Federal do Paraná. Setor de Ciências Biológicas. Departamento de Patologia Básica. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Institut Pasteur de Montevideo. Functional Genomics Unit. Mataojo, Montevideo, Uruguay.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil.Small non-coding RNAs derived from transfer RNAs have been identified as a broadly conserved prokaryotic and eukaryotic response to stress. Their presence coincides with changes in developmental state associated with gene expression regulation. In the epimastigote form of Trypanosoma cruzi, tRNA fragments localize to posterior cytoplasmic granules. In the infective metacyclic form of the parasite, we found tRNA-derived fragments to be abundant and evenly distributed within the cytoplasm. The fragments were not associated with polysomes, suggesting that the tRNA-derived fragments may not be directly involved in translation control in metacyclics.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/39854/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINAL18ok.pdf18ok.pdfapplication/pdf1014930https://www.arca.fiocruz.br/bitstream/icict/39854/2/18ok.pdf7a1d5de53f621655a7ec36549f5423e8MD52TEXT18ok.pdf.txt18ok.pdf.txtExtracted texttext/plain42156https://www.arca.fiocruz.br/bitstream/icict/39854/3/18ok.pdf.txt5b73934afb7fbd1187b207a671b0d694MD53icict/398542020-04-09 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dc.title.pt_BR.fl_str_mv Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
title Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
spellingShingle Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
Reifur, Larissa
Trypanosoma cruzi
TRNA
RNA, Transfer
RNA, Untranslated
Stress, Physiological
Molecular Structure
ARN de Transferencia
ARN no Traducido
Estrés Fisiológico
Estructura Molecular
RNA de Transferência
RNA não Traduzido
Estresse Fisiológico
Estrutura Molecular
title_short Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
title_full Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
title_fullStr Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
title_full_unstemmed Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
title_sort Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi
author Reifur, Larissa
author_facet Reifur, Larissa
Garcia-Silva, Maria Rosa
Poubel, Saloê Bispo
Alves, Lysangela Ronalte
Arauco, Paulo
Buiar, Diane Kelly
Goldenberg, Samuel
Cayota, Alfonso
Dallagiovanna, Bruno
author_role author
author2 Garcia-Silva, Maria Rosa
Poubel, Saloê Bispo
Alves, Lysangela Ronalte
Arauco, Paulo
Buiar, Diane Kelly
Goldenberg, Samuel
Cayota, Alfonso
Dallagiovanna, Bruno
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Reifur, Larissa
Garcia-Silva, Maria Rosa
Poubel, Saloê Bispo
Alves, Lysangela Ronalte
Arauco, Paulo
Buiar, Diane Kelly
Goldenberg, Samuel
Cayota, Alfonso
Dallagiovanna, Bruno
dc.subject.other.pt_BR.fl_str_mv Trypanosoma cruzi
TRNA
topic Trypanosoma cruzi
TRNA
RNA, Transfer
RNA, Untranslated
Stress, Physiological
Molecular Structure
ARN de Transferencia
ARN no Traducido
Estrés Fisiológico
Estructura Molecular
RNA de Transferência
RNA não Traduzido
Estresse Fisiológico
Estrutura Molecular
dc.subject.en.pt_BR.fl_str_mv RNA, Transfer
RNA, Untranslated
Stress, Physiological
Molecular Structure
dc.subject.es.pt_BR.fl_str_mv ARN de Transferencia
ARN no Traducido
Estrés Fisiológico
Estructura Molecular
dc.subject.decs.pt_BR.fl_str_mv RNA de Transferência
RNA não Traduzido
Estresse Fisiológico
Estrutura Molecular
description Fundação Oswaldo Cruz. Instituto Carlos Chagas. Curitiba, PR, Brasil. / Universidade Federal do Paraná. Setor de Ciências Biológicas. Departamento de Patologia Básica. Curitiba, PR, Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2020-02-11T15:01:02Z
dc.date.available.fl_str_mv 2020-02-11T15:01:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv REIFUR, Larissa et al. Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.107, n. 6, p. 816–819, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/39854
dc.identifier.issn.pt_BR.fl_str_mv 1678-8060
dc.identifier.doi.none.fl_str_mv 10.1590/s0074-02762012000600018
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv REIFUR, Larissa et al. Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v.107, n. 6, p. 816–819, 2012.
1678-8060
10.1590/s0074-02762012000600018
url https://www.arca.fiocruz.br/handle/icict/39854
dc.language.iso.fl_str_mv por
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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