Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae

Detalhes bibliográficos
Autor(a) principal: Lopes, Ana Carolina Amaral
Data de Publicação: 2015
Outros Autores: Martins, Luciano Moura, Gatti, Maria Silvia Viccari, Reis, Christiane Moura Falavina dos, Hofer, Ernesto, Yano, Tomomasa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/13198
Resumo: Universidade Estadual de Campinas. Departamento de Genética, Evolução e Bioagentes. Campinas, SP, Brasil.
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spelling Lopes, Ana Carolina AmaralMartins, Luciano MouraGatti, Maria Silvia ViccariReis, Christiane Moura Falavina dosHofer, ErnestoYano, Tomomasa2016-03-17T15:11:36Z2016-03-17T15:11:36Z2015LOPES, Ana Carolina Amaral; et al. Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae. Rev. Inst. Med. trop. S. Paulo, v.57, n.4, p. 349-351, July/Aug. 2015.1678-9946https://www.arca.fiocruz.br/handle/icict/1319810.1590/S0036-46652015000400013engInstituto de Medicina Tropical de São PauloDiarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviaeO surto de diarreia em Pernambuco, Brasil é associado com uma enterotoxina citotóxica termo-estável produzida por Aeromonas caviaeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Estadual de Campinas. Departamento de Genética, Evolução e Bioagentes. Campinas, SP, Brasil.Instituto Adolfo Lutz. Centro de Bacteriologia. Departamento de Doenças Infecciosas. São Paulo, SP, Brasil.Universidade Estadual de Campinas. Departamento de Genética, Evolução e Bioagentes. Campinas, SP, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bacteriologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bacteriologia. Rio de Janeiro, RJ, Brasil.In the present study enterotoxic and cytotoxic activities of twenty Aeromonas caviae strains were examined. They originated from fecal specimens of patients with acute diarrhea during an outbreak in Brazil in 2004. Culture supernatants of fourteen strains (70%) caused fluid accumulation in rabbit ileal intestinal loops and in suckling mice assays, and also showed a cytotoxic activity in Vero and Caco-2 cells. The enterotoxic and cytotoxic factors were heat-stable after culture supernatants treatment at 100 ºC. The results revealed that A. caviae strains produce a putative diarrheagenic virulence factor, a heat-stable cytotoxic enterotoxin that could be linked to the diarrhea outbreak that took place in Brazil.Diarrhea outbreakAeromonas caviaeCytotoxic enterotoxinVirulence factorsPernambucoBrazilFatores de VirulênciaCitotoxinasAeromonas caviaeDiarreiaBrazilinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/13198/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALernesto_hofer_etal_IOC_2015.pdfernesto_hofer_etal_IOC_2015.pdfapplication/pdf967912https://www.arca.fiocruz.br/bitstream/icict/13198/2/ernesto_hofer_etal_IOC_2015.pdf3e801253378a181635866064b1b67f62MD52TEXTernesto_hofer_etal_IOC_2015.pdf.txternesto_hofer_etal_IOC_2015.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
dc.title.alternative.pt_BR.fl_str_mv O surto de diarreia em Pernambuco, Brasil é associado com uma enterotoxina citotóxica termo-estável produzida por Aeromonas caviae
title Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
spellingShingle Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
Lopes, Ana Carolina Amaral
Diarrhea outbreak
Aeromonas caviae
Cytotoxic enterotoxin
Virulence factors
Pernambuco
Brazil
Fatores de Virulência
Citotoxinas
Aeromonas caviae
Diarreia
Brazil
title_short Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
title_full Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
title_fullStr Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
title_full_unstemmed Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
title_sort Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae
author Lopes, Ana Carolina Amaral
author_facet Lopes, Ana Carolina Amaral
Martins, Luciano Moura
Gatti, Maria Silvia Viccari
Reis, Christiane Moura Falavina dos
Hofer, Ernesto
Yano, Tomomasa
author_role author
author2 Martins, Luciano Moura
Gatti, Maria Silvia Viccari
Reis, Christiane Moura Falavina dos
Hofer, Ernesto
Yano, Tomomasa
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Lopes, Ana Carolina Amaral
Martins, Luciano Moura
Gatti, Maria Silvia Viccari
Reis, Christiane Moura Falavina dos
Hofer, Ernesto
Yano, Tomomasa
dc.subject.en.pt_BR.fl_str_mv Diarrhea outbreak
Aeromonas caviae
Cytotoxic enterotoxin
Virulence factors
Pernambuco
Brazil
topic Diarrhea outbreak
Aeromonas caviae
Cytotoxic enterotoxin
Virulence factors
Pernambuco
Brazil
Fatores de Virulência
Citotoxinas
Aeromonas caviae
Diarreia
Brazil
dc.subject.decs.pt_BR.fl_str_mv Fatores de Virulência
Citotoxinas
Aeromonas caviae
Diarreia
Brazil
description Universidade Estadual de Campinas. Departamento de Genética, Evolução e Bioagentes. Campinas, SP, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2016-03-17T15:11:36Z
dc.date.available.fl_str_mv 2016-03-17T15:11:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LOPES, Ana Carolina Amaral; et al. Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae. Rev. Inst. Med. trop. S. Paulo, v.57, n.4, p. 349-351, July/Aug. 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/13198
dc.identifier.issn.none.fl_str_mv 1678-9946
dc.identifier.doi.none.fl_str_mv 10.1590/S0036-46652015000400013
identifier_str_mv LOPES, Ana Carolina Amaral; et al. Diarrhea outbreak in Pernambuco, Brazil, associated with a heat-stable cytotoxic enterotoxin produced by Aeromonas caviae. Rev. Inst. Med. trop. S. Paulo, v.57, n.4, p. 349-351, July/Aug. 2015.
1678-9946
10.1590/S0036-46652015000400013
url https://www.arca.fiocruz.br/handle/icict/13198
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Instituto de Medicina Tropical de São Paulo
publisher.none.fl_str_mv Instituto de Medicina Tropical de São Paulo
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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