Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity

Detalhes bibliográficos
Autor(a) principal: Gomes, Regis Bernardo Brandim
Data de Publicação: 2002
Outros Autores: Brodskyn, Claudia Ida, Oliveira, Camila Indiani de, Costa, Jackson Mauricio Lopes, Miranda, José Carlos, Caldas, Arlene de Jesus Mendes, Valenzuela, Jesus G, Barral Netto, Manoel, Barral, Aldina Maria Prado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/4198
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
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spelling Gomes, Regis Bernardo BrandimBrodskyn, Claudia IdaOliveira, Camila Indiani deCosta, Jackson Mauricio LopesMiranda, José CarlosCaldas, Arlene de Jesus MendesValenzuela, Jesus GBarral Netto, ManoelBarral, Aldina Maria Prado2012-07-18T20:56:40Z2012-07-18T20:56:40Z2002GOMES, R.B. et al. Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity. Journal of Infectious Disease, v. 186, n. 10, p. 1530-4, nov. 2002.0022-1899https://www.arca.fiocruz.br/handle/icict/4198engSeroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal do Maranhão. São Luis, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.National Institute of Allergy and Infectious Diseases. National Institutes of Health. Bethesda, MarylandFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilAntibody responses to salivary gland sonicate (SGS) from Lutzomyia longipalpis were investigated using serum samples from individuals living in an area where visceral leishmaniasis is endemic. Individuals were classified into 2 groups, according to the alteration of their responses to Leishmania chagasi antigen over the course of 6 months. Group 1 included children who experienced anti-L. chagasi seroconversion from negative to positive; group 2 included children who experienced delayed-type hypersensitivity (DTH) response to L. chagasi antigen conversion from negative to positive. Individuals who experienced seroconversion against L. chagasi antigens did not have increased anti-saliva antibody response, whereas those who developed a positive anti-L. chagasi DTH response had increased immunoglobulin (Ig) G, IgG1 and IgE anti-SGS antibody levels. Despite wide variation, serum samples from individuals in group 2 recognized more bands in SGS than did those from individuals in group 1. This simultaneous appearance of anti-saliva humoral response and anti-L. chagasi cell-mediated immunity supports the hypothesis that induction of immune response against SGS can facilitate induction of a protective response against leishmaniasisDoenças EndêmicasHipersensibilidade Tardia/imunologiaImunoglobulina G/imunologiaLeishmania/imunologiaLeishmaniose/imunologiaPsychodidae/imunologiaFormação de Anticorpos/imunologiaCriançaHumanosImunidade Celular/imunologiaLeishmaniose/epidemiologiaGlândulas Salivares/imunologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALGomes RB Seroconversion against Lutzomyia....pdfGomes RB Seroconversion against Lutzomyia....pdfapplication/pdf155319https://www.arca.fiocruz.br/bitstream/icict/4198/1/Gomes%20RB%20Seroconversion%20against%20Lutzomyia....pdf0566cb0a4cbac4610768535c99709448MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81990https://www.arca.fiocruz.br/bitstream/icict/4198/2/license.txtb6ead4607e393dee1190c21ba08397beMD52TEXTGomes RB Seroconversion against Lutzomyia....pdf.txtGomes RB Seroconversion against Lutzomyia....pdf.txtExtracted texttext/plain22334https://www.arca.fiocruz.br/bitstream/icict/4198/5/Gomes%20RB%20Seroconversion%20against%20Lutzomyia....pdf.txt21a3e9f2bb92c1521b4e23a17f815773MD55THUMBNAILGomes RB Seroconversion against Lutzomyia....pdf.jpgGomes RB Seroconversion against Lutzomyia....pdf.jpgGenerated Thumbnailimage/jpeg2183https://www.arca.fiocruz.br/bitstream/icict/4198/4/Gomes%20RB%20Seroconversion%20against%20Lutzomyia....pdf.jpg46decadbf7a273a0ee7261cecf7641a1MD54icict/41982023-09-14 15:46:53.565oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-09-14T18:46:53Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
title Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
spellingShingle Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
Gomes, Regis Bernardo Brandim
Doenças Endêmicas
Hipersensibilidade Tardia/imunologia
Imunoglobulina G/imunologia
Leishmania/imunologia
Leishmaniose/imunologia
Psychodidae/imunologia
Formação de Anticorpos/imunologia
Criança
Humanos
Imunidade Celular/imunologia
Leishmaniose/epidemiologia
Glândulas Salivares/imunologia
title_short Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
title_full Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
title_fullStr Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
title_full_unstemmed Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
title_sort Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity
author Gomes, Regis Bernardo Brandim
author_facet Gomes, Regis Bernardo Brandim
Brodskyn, Claudia Ida
Oliveira, Camila Indiani de
Costa, Jackson Mauricio Lopes
Miranda, José Carlos
Caldas, Arlene de Jesus Mendes
Valenzuela, Jesus G
Barral Netto, Manoel
Barral, Aldina Maria Prado
author_role author
author2 Brodskyn, Claudia Ida
Oliveira, Camila Indiani de
Costa, Jackson Mauricio Lopes
Miranda, José Carlos
Caldas, Arlene de Jesus Mendes
Valenzuela, Jesus G
Barral Netto, Manoel
Barral, Aldina Maria Prado
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gomes, Regis Bernardo Brandim
Brodskyn, Claudia Ida
Oliveira, Camila Indiani de
Costa, Jackson Mauricio Lopes
Miranda, José Carlos
Caldas, Arlene de Jesus Mendes
Valenzuela, Jesus G
Barral Netto, Manoel
Barral, Aldina Maria Prado
dc.subject.decs.pt_BR.fl_str_mv Doenças Endêmicas
Hipersensibilidade Tardia/imunologia
Imunoglobulina G/imunologia
Leishmania/imunologia
Leishmaniose/imunologia
Psychodidae/imunologia
Formação de Anticorpos/imunologia
Criança
Humanos
Imunidade Celular/imunologia
Leishmaniose/epidemiologia
Glândulas Salivares/imunologia
topic Doenças Endêmicas
Hipersensibilidade Tardia/imunologia
Imunoglobulina G/imunologia
Leishmania/imunologia
Leishmaniose/imunologia
Psychodidae/imunologia
Formação de Anticorpos/imunologia
Criança
Humanos
Imunidade Celular/imunologia
Leishmaniose/epidemiologia
Glândulas Salivares/imunologia
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
publishDate 2002
dc.date.issued.fl_str_mv 2002
dc.date.accessioned.fl_str_mv 2012-07-18T20:56:40Z
dc.date.available.fl_str_mv 2012-07-18T20:56:40Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv GOMES, R.B. et al. Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity. Journal of Infectious Disease, v. 186, n. 10, p. 1530-4, nov. 2002.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/4198
dc.identifier.issn.none.fl_str_mv 0022-1899
identifier_str_mv GOMES, R.B. et al. Seroconversion against Lutzomyia longipalpis saliva concurrent with the development of anti-Leishmania chagasi delayed-type hypersensitivity. Journal of Infectious Disease, v. 186, n. 10, p. 1530-4, nov. 2002.
0022-1899
url https://www.arca.fiocruz.br/handle/icict/4198
dc.language.iso.fl_str_mv eng
language eng
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dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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