Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen

Detalhes bibliográficos
Autor(a) principal: Aquino, Dorlene Maria Cardoso de
Data de Publicação: 2010
Outros Autores: Caldas, Arlene de Jesus Mendes, Miranda, José Carlos, Silva, Antonio Augusto Moura da, Barral Netto, Manoel, Barral, Aldina Maria Prado
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/7387
Resumo: Universidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, Brasil
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spelling Aquino, Dorlene Maria Cardoso deCaldas, Arlene de Jesus MendesMiranda, José CarlosSilva, Antonio Augusto Moura daBarral Netto, ManoelBarral, Aldina Maria Prado2014-03-10T17:04:07Z2014-03-10T17:04:07Z2010AQUINO, D. M. C. et al. Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. American Journal of Tropical Medicine and Hygiene, v.83, n. 4, p.825-827, 2010.1476-1645https://www.arca.fiocruz.br/handle/icict/738710.4269/ajtmh.2010.10-0182engThe American Society of Tropical Medicine and HygieneEpidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigeninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, BrasilUniversidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilUniversidade Federal do Maranhão. Departamento de Saúde Pública. São Luís, MA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Imuno-regulação. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia iii - INCT. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Imunoparasitologia. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Investigação em Imunologia iii - INCT. Salvador, BA, BrasilRecent reports from animal models and from cross-sectional studies have suggested that host responses to anti-Lutzomyia longipalpis saliva antibodies may be related to delayed-type hypersensitivity to Leishmania antigen. In a prospective cohort study, we evaluated 1,080 children from two endemic areas for visceral leishmaniasis (VL) by means of Kaplan-Meier analysis. The incidence rate of delayed-type hypersensitivity to Leishmania antigen, measured at the 24th follow-up month, was higher among those reactive to Lu. longipalpis saliva antibodies at the beginning of the study (0.0217 cases per person-month) than among those previously negative (0.0131 cases per person-month) (P value for the log-rank test = 0.0006). It seems that mounting an anti-saliva immune response helps the development of a cell-mediated anti-Leishmania response.Anticorpos/sangueAntígenos de Protozoários/imunologiaHipersensibilidade Tardia/etiologiaLeishmania/imunologiaLeishmaniose Visceral/diagnósticoPsychodidae/imunologiaAnimaisCriançaPré-EscolarEstudos de CoortesHumanosHipersensibilidade Tardia/imunologiaLactenteLeishmaniose Visceral/imunologiaRecém-Nascidoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALAquino D M C Epidemiological Study....pdfAquino D M C Epidemiological Study....pdfapplication/pdf557538https://www.arca.fiocruz.br/bitstream/icict/7387/1/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf95382594fd4746a392752483557e5fdbMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/7387/2/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD52TEXTAquino D M C Epidemiological Study....pdf.txtAquino D M C Epidemiological Study....pdf.txtExtracted texttext/plain17893https://www.arca.fiocruz.br/bitstream/icict/7387/5/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf.txt04956102f059d7846da9fd7cfb15e724MD55THUMBNAILAquino D M C Epidemiological Study....pdf.jpgAquino D M C Epidemiological Study....pdf.jpgGenerated Thumbnailimage/jpeg2345https://www.arca.fiocruz.br/bitstream/icict/7387/4/Aquino%20D%20M%20C%20Epidemiological%20Study....pdf.jpgbe392372f7587ae7274c201d5988abbdMD54icict/73872023-03-15 14:33:26.611oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:26Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
title Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
spellingShingle Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
Aquino, Dorlene Maria Cardoso de
Anticorpos/sangue
Antígenos de Protozoários/imunologia
Hipersensibilidade Tardia/etiologia
Leishmania/imunologia
Leishmaniose Visceral/diagnóstico
Psychodidae/imunologia
Animais
Criança
Pré-Escolar
Estudos de Coortes
Humanos
Hipersensibilidade Tardia/imunologia
Lactente
Leishmaniose Visceral/imunologia
Recém-Nascido
title_short Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
title_full Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
title_fullStr Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
title_full_unstemmed Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
title_sort Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen
author Aquino, Dorlene Maria Cardoso de
author_facet Aquino, Dorlene Maria Cardoso de
Caldas, Arlene de Jesus Mendes
Miranda, José Carlos
Silva, Antonio Augusto Moura da
Barral Netto, Manoel
Barral, Aldina Maria Prado
author_role author
author2 Caldas, Arlene de Jesus Mendes
Miranda, José Carlos
Silva, Antonio Augusto Moura da
Barral Netto, Manoel
Barral, Aldina Maria Prado
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Aquino, Dorlene Maria Cardoso de
Caldas, Arlene de Jesus Mendes
Miranda, José Carlos
Silva, Antonio Augusto Moura da
Barral Netto, Manoel
Barral, Aldina Maria Prado
dc.subject.decs.pt_BR.fl_str_mv Anticorpos/sangue
Antígenos de Protozoários/imunologia
Hipersensibilidade Tardia/etiologia
Leishmania/imunologia
Leishmaniose Visceral/diagnóstico
Psychodidae/imunologia
Animais
Criança
Pré-Escolar
Estudos de Coortes
Humanos
Hipersensibilidade Tardia/imunologia
Lactente
Leishmaniose Visceral/imunologia
Recém-Nascido
topic Anticorpos/sangue
Antígenos de Protozoários/imunologia
Hipersensibilidade Tardia/etiologia
Leishmania/imunologia
Leishmaniose Visceral/diagnóstico
Psychodidae/imunologia
Animais
Criança
Pré-Escolar
Estudos de Coortes
Humanos
Hipersensibilidade Tardia/imunologia
Lactente
Leishmaniose Visceral/imunologia
Recém-Nascido
description Universidade Federal do Maranhão. Departamento de Enfermagem. São Luís, MA, Brasil
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2014-03-10T17:04:07Z
dc.date.available.fl_str_mv 2014-03-10T17:04:07Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AQUINO, D. M. C. et al. Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. American Journal of Tropical Medicine and Hygiene, v.83, n. 4, p.825-827, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/7387
dc.identifier.issn.none.fl_str_mv 1476-1645
dc.identifier.doi.none.fl_str_mv 10.4269/ajtmh.2010.10-0182
identifier_str_mv AQUINO, D. M. C. et al. Epidemiological study of the association between anti-Lutzomyia longipalpis saliva antibodies and development of delayed-type hypersensitivity to Leishmania antigen. American Journal of Tropical Medicine and Hygiene, v.83, n. 4, p.825-827, 2010.
1476-1645
10.4269/ajtmh.2010.10-0182
url https://www.arca.fiocruz.br/handle/icict/7387
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv The American Society of Tropical Medicine and Hygiene
publisher.none.fl_str_mv The American Society of Tropical Medicine and Hygiene
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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