Implications of high level pseudogene transcription in Mycobacterium leprae

Detalhes bibliográficos
Autor(a) principal: Williams, Diana L.
Data de Publicação: 2009
Outros Autores: Slayden, Richard A., Amin, Amol, Martinez, Alejandra N., Pittman, Tana L., Mira, Alex, Mitra, Anirban, Nagaraja, Valakunja, Morrison, Norman E., Moraes, Milton, Gillis, Thomas P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/29049
Resumo: HRSA, BPHC, Division of National Hansen's Disease Programs. Laboratory Research Branch. Molecular Biology Research Department. School of Veterinary Medicine. Louisiana State University. Baton Rouge, LA, USA.
id CRUZ_ac6b8a2d9f350ee68008ea1232b70d4c
oai_identifier_str oai:www.arca.fiocruz.br:icict/29049
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Williams, Diana L.Slayden, Richard A.Amin, AmolMartinez, Alejandra N.Pittman, Tana L.Mira, AlexMitra, AnirbanNagaraja, ValakunjaMorrison, Norman E.Moraes, MiltonGillis, Thomas P.2018-09-25T17:04:45Z2018-09-25T17:04:45Z2009WILLIAMS, Diana L. et al. Implications of high level pseudogene transcription in Mycobacterium leprae. BMC Genomics, v.10, n.397, 20p, Aug. 2009.1471-2164https://www.arca.fiocruz.br/handle/icict/2904910.1186/1471-2164-10-397engBioMed CentralMycobacterium lepraeHanseníasePseudogenesfisiologiagenomaMycobacterium lepraeLeprosypseudogene transcriptionalM. leprae physiologygenomeImplications of high level pseudogene transcription in Mycobacterium lepraeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHRSA, BPHC, Division of National Hansen's Disease Programs. Laboratory Research Branch. Molecular Biology Research Department. School of Veterinary Medicine. Louisiana State University. Baton Rouge, LA, USA.Rocky Mountain Regional Center of Excellence. Department of Microbiology, Immunology & Pathology. Colorado State University. Fort Collins, CO, USA.Rocky Mountain Regional Center of Excellence. Department of Microbiology, Immunology & Pathology. Colorado State University. Fort Collins, CO, USA.HRSA, BPHC, Division of National Hansen's Disease Programs. Laboratory Research Branch. Molecular Biology Research Department. School of Veterinary Medicine. Louisiana State University. Baton Rouge, LA, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Laboratório de Hanseníase. Rio de Janeiro, RJ, BrasilHRSA, BPHC, Division of National Hansen's Disease Programs. Laboratory Research Branch. Molecular Biology Research Department. School of Veterinary Medicine. Louisiana State University. Baton Rouge, LA, USA.Center for Advanced Research in Public Health. CSISP, Area de Genomica y Salud. Valencia, Spain.Indian Institute of Science. Department of Microbiology and Cell Biology. Bangalore, India.Indian Institute of Science. Department of Microbiology and Cell Biology. Bangalore, India.Johns Hopkins School of Medicine. Division of Infectious Diseases. Department of Medicine. Center for Tuberculosis Research. Baltimore, MD, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Laboratório de Hanseníase. Rio de Janeiro, RJ, BrasilHRSA, BPHC, Division of National Hansen's Disease Programs. Laboratory Research Branch. Molecular Biology Research Department. School of Veterinary Medicine. Louisiana State University. Baton Rouge, LA, USA.The Mycobacterium leprae genome has less than 50% coding capacity and 1,133 pseudogenes. Preliminary evidence suggests that some pseudogenes are expressed. Therefore, defining pseudogene transcriptional and translational potentials of this genome should increase our understanding of their impact on M. leprae physiology.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/29049/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALalejandra_martinez_etal_IOC_2009.pdfalejandra_martinez_etal_IOC_2009.pdfapplication/pdf609588https://www.arca.fiocruz.br/bitstream/icict/29049/2/alejandra_martinez_etal_IOC_2009.pdf52f46c1961ad3a79a011f4c11b6d8de0MD52TEXTalejandra_martinez_etal_IOC_2009.pdf.txtalejandra_martinez_etal_IOC_2009.pdf.txtExtracted texttext/plain89513https://www.arca.fiocruz.br/bitstream/icict/29049/3/alejandra_martinez_etal_IOC_2009.pdf.txt0c177d718a2665aec2b62627d3d34760MD53icict/290492018-09-26 02:01:21.076oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352018-09-26T05:01:21Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Implications of high level pseudogene transcription in Mycobacterium leprae
title Implications of high level pseudogene transcription in Mycobacterium leprae
spellingShingle Implications of high level pseudogene transcription in Mycobacterium leprae
Williams, Diana L.
Mycobacterium leprae
Hanseníase
Pseudogenes
fisiologia
genoma
Mycobacterium leprae
Leprosy
pseudogene transcriptional
M. leprae physiology
genome
title_short Implications of high level pseudogene transcription in Mycobacterium leprae
title_full Implications of high level pseudogene transcription in Mycobacterium leprae
title_fullStr Implications of high level pseudogene transcription in Mycobacterium leprae
title_full_unstemmed Implications of high level pseudogene transcription in Mycobacterium leprae
title_sort Implications of high level pseudogene transcription in Mycobacterium leprae
author Williams, Diana L.
author_facet Williams, Diana L.
Slayden, Richard A.
Amin, Amol
Martinez, Alejandra N.
Pittman, Tana L.
Mira, Alex
Mitra, Anirban
Nagaraja, Valakunja
Morrison, Norman E.
Moraes, Milton
Gillis, Thomas P.
author_role author
author2 Slayden, Richard A.
Amin, Amol
Martinez, Alejandra N.
Pittman, Tana L.
Mira, Alex
Mitra, Anirban
Nagaraja, Valakunja
Morrison, Norman E.
Moraes, Milton
Gillis, Thomas P.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Williams, Diana L.
Slayden, Richard A.
Amin, Amol
Martinez, Alejandra N.
Pittman, Tana L.
Mira, Alex
Mitra, Anirban
Nagaraja, Valakunja
Morrison, Norman E.
Moraes, Milton
Gillis, Thomas P.
dc.subject.other.pt_BR.fl_str_mv Mycobacterium leprae
Hanseníase
Pseudogenes
fisiologia
genoma
topic Mycobacterium leprae
Hanseníase
Pseudogenes
fisiologia
genoma
Mycobacterium leprae
Leprosy
pseudogene transcriptional
M. leprae physiology
genome
dc.subject.en.pt_BR.fl_str_mv Mycobacterium leprae
Leprosy
pseudogene transcriptional
M. leprae physiology
genome
description HRSA, BPHC, Division of National Hansen's Disease Programs. Laboratory Research Branch. Molecular Biology Research Department. School of Veterinary Medicine. Louisiana State University. Baton Rouge, LA, USA.
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2018-09-25T17:04:45Z
dc.date.available.fl_str_mv 2018-09-25T17:04:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv WILLIAMS, Diana L. et al. Implications of high level pseudogene transcription in Mycobacterium leprae. BMC Genomics, v.10, n.397, 20p, Aug. 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/29049
dc.identifier.issn.pt_BR.fl_str_mv 1471-2164
dc.identifier.doi.none.fl_str_mv 10.1186/1471-2164-10-397
identifier_str_mv WILLIAMS, Diana L. et al. Implications of high level pseudogene transcription in Mycobacterium leprae. BMC Genomics, v.10, n.397, 20p, Aug. 2009.
1471-2164
10.1186/1471-2164-10-397
url https://www.arca.fiocruz.br/handle/icict/29049
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/29049/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/29049/2/alejandra_martinez_etal_IOC_2009.pdf
https://www.arca.fiocruz.br/bitstream/icict/29049/3/alejandra_martinez_etal_IOC_2009.pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
52f46c1961ad3a79a011f4c11b6d8de0
0c177d718a2665aec2b62627d3d34760
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008943429976064

Registros relacionados