KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection

Detalhes bibliográficos
Autor(a) principal: Chamon, Raiane Cardoso
Data de Publicação: 2020
Outros Autores: Rocha, Jaqueline Abel da, Martins, Isabella Araujo, Pires, Laís Lopes, Almeida, Breno Macêdo de, Leite, Nahara Souza, Souza, Cláudia Rezende Vieira de Mendonça, Zahner, Viviane, Ribeiro, Rachel Leite, Chagas, Thiago Pavoni Gomes, Martins, Ianick Souto
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42378
Resumo: Universidade Federal Fluminense, Escola de Medicina. Departamento de Patologia. Niterói, RJ, Brasil.
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spelling Chamon, Raiane CardosoRocha, Jaqueline Abel daMartins, Isabella AraujoPires, Laís LopesAlmeida, Breno Macêdo deLeite, Nahara SouzaSouza, Cláudia Rezende Vieira de MendonçaZahner, VivianeRibeiro, Rachel LeiteChagas, Thiago Pavoni GomesMartins, Ianick Souto2020-07-24T18:24:17Z2020-07-24T18:24:17Z2020CHAMON, Raiane Cardoso et al. KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection. Journal of Infection in Developing Countries, v. 14, n. 4, p. 411-414, 2020.2036-6590https://www.arca.fiocruz.br/handle/icict/4237810.3855/jidc.121451972-2680engJournal of Infection in Developing CountriesPseudomonas putidaKlebsiella pneumoniae carbapenemaseInfecção por corrente sanguínea;KPCPseudomonas putidaBloodstream infectionKlebsiella pneumoniae carbapenemaseKPCKPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Fluminense, Escola de Medicina. Departamento de Patologia. Niterói, RJ, Brasil.Universidade Federal Fluminense, Escola de Medicina. Hospital Universitário Antonio Pedro. Niterói, RJ, Brasil.Universidade Federal Fluminense, Escola de Medicina. Hospital Universitário Antonio Pedro. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense, Escola de Medicina. Departamento de Patologia. Niterói, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense, Escola de Medicina. Departamento de Patologia. Niterói, RJ, Brasil.Universidade Federal Fluminense, Escola de Medicina. Departamento de Patologia. Niterói, RJ, Brasil.Universidade Federal Fluminense, Escola de Medicina. Departamento de Medicina Interna. Seção de Doenças Infecciosas. Niterói, RJ, Brasil / Instituto Nacional de Câncer. Hospital do CÂncer. Comissão de Controle Hospitalar. Rio de Janeiro, RJ, Brasil.Infections due to multidrug resistant Gram-negative pathogens are of great concern worldwide, as they are frequently associated with high mortality and morbidity rates. The occurrence of Pseudomonas spp. producing Klebsiella pneumoniae carbapenemases (KPCs) imposes a great challenge through treatment course of bloodstream infections (BSIs). Pseudomonas putida has been recognized as an emerging pathogen of healthcare associated infections (HAIs). Therefore, we aimed to report a case of a non-fatal case of peripheral line associated BSI (PLA-BSI) in an immunocompromised host due to P. putida harboring blaKPC-2 gene in Brazil. A P. putida isolate was recovered from a blood culture of a 72-year-old man admitted at a University Hospital, identified by BD Phoenix™ 100 (Becton, Dickinson and Company), causing PLA-BSI. The species identification was confirmed by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and resistance to carbapenems were confirmed by Epsilometer test (E-test®). Additionally, the presence of important carbapenemases genes (blaKPC, blaNDM, blaOXA-48-like, blaSPM, blaIMP, blaVIM) was investigated by Polymerase Chain Reaction. The bacterial isolate was confirmed as meropenem resistant P. putida harboring blaKPC-2 gene.Thereofre, these fidings suggest that P. putida can work as a reservoir for resistance genes as this bacterium has the ability to disseminate through water-fluids inside hospital and community settings. Moreover, this paper highlights that a frequent and worldwide disseminated mechanism of resistance (blaKPC-2) is currently occurring among uncommon agents of BSI.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/42378/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALViviane_Zhaner_etal_IOC_2020.pdfViviane_Zhaner_etal_IOC_2020.pdfapplication/pdf370429https://www.arca.fiocruz.br/bitstream/icict/42378/2/Viviane_Zhaner_etal_IOC_2020.pdfd2b46729baac3b671d023eea9cfcdfe3MD52TEXTViviane_Zhaner_etal_IOC_2020.pdf.txtViviane_Zhaner_etal_IOC_2020.pdf.txtExtracted texttext/plain18580https://www.arca.fiocruz.br/bitstream/icict/42378/3/Viviane_Zhaner_etal_IOC_2020.pdf.txtd9a98ae75f8eecad997b0c256c5bd764MD53icict/423782020-07-25 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dc.title.pt_BR.fl_str_mv KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
title KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
spellingShingle KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
Chamon, Raiane Cardoso
Pseudomonas putida
Klebsiella pneumoniae carbapenemase
Infecção por corrente sanguínea;
KPC
Pseudomonas putida
Bloodstream infection
Klebsiella pneumoniae carbapenemase
KPC
title_short KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
title_full KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
title_fullStr KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
title_full_unstemmed KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
title_sort KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection
author Chamon, Raiane Cardoso
author_facet Chamon, Raiane Cardoso
Rocha, Jaqueline Abel da
Martins, Isabella Araujo
Pires, Laís Lopes
Almeida, Breno Macêdo de
Leite, Nahara Souza
Souza, Cláudia Rezende Vieira de Mendonça
Zahner, Viviane
Ribeiro, Rachel Leite
Chagas, Thiago Pavoni Gomes
Martins, Ianick Souto
author_role author
author2 Rocha, Jaqueline Abel da
Martins, Isabella Araujo
Pires, Laís Lopes
Almeida, Breno Macêdo de
Leite, Nahara Souza
Souza, Cláudia Rezende Vieira de Mendonça
Zahner, Viviane
Ribeiro, Rachel Leite
Chagas, Thiago Pavoni Gomes
Martins, Ianick Souto
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Chamon, Raiane Cardoso
Rocha, Jaqueline Abel da
Martins, Isabella Araujo
Pires, Laís Lopes
Almeida, Breno Macêdo de
Leite, Nahara Souza
Souza, Cláudia Rezende Vieira de Mendonça
Zahner, Viviane
Ribeiro, Rachel Leite
Chagas, Thiago Pavoni Gomes
Martins, Ianick Souto
dc.subject.other.pt_BR.fl_str_mv Pseudomonas putida
Klebsiella pneumoniae carbapenemase
Infecção por corrente sanguínea;
KPC
topic Pseudomonas putida
Klebsiella pneumoniae carbapenemase
Infecção por corrente sanguínea;
KPC
Pseudomonas putida
Bloodstream infection
Klebsiella pneumoniae carbapenemase
KPC
dc.subject.en.pt_BR.fl_str_mv Pseudomonas putida
Bloodstream infection
Klebsiella pneumoniae carbapenemase
KPC
description Universidade Federal Fluminense, Escola de Medicina. Departamento de Patologia. Niterói, RJ, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-07-24T18:24:17Z
dc.date.available.fl_str_mv 2020-07-24T18:24:17Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CHAMON, Raiane Cardoso et al. KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection. Journal of Infection in Developing Countries, v. 14, n. 4, p. 411-414, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42378
dc.identifier.issn.pt_BR.fl_str_mv 2036-6590
dc.identifier.doi.none.fl_str_mv 10.3855/jidc.12145
dc.identifier.eissn.none.fl_str_mv 1972-2680
identifier_str_mv CHAMON, Raiane Cardoso et al. KPC-2 producing Pseudomonas putida as an unexpected pathogen of catheter-associated bloodstream infection. Journal of Infection in Developing Countries, v. 14, n. 4, p. 411-414, 2020.
2036-6590
10.3855/jidc.12145
1972-2680
url https://www.arca.fiocruz.br/handle/icict/42378
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Journal of Infection in Developing Countries
publisher.none.fl_str_mv Journal of Infection in Developing Countries
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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