Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/34626 |
Resumo: | Pfizer Inc. The Brazilian Study of Diabetes Control was funded by Pfizer Inc., Brazil. Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. EDMJ received support from the National Council for Scientific and Technological Development (CNPq). |
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Duarte, Fernanda GrossMoreira, Sandra da SilvaAlmeida, Maria da Conceição Chagas deTeles, Carlos A de SouzaAndrade, Carine de SousaReingold, Art L.Moreira Junior, Edson Duarte2019-08-06T16:36:12Z2019-08-06T16:36:12Z2019DUARTE, Fernanda Gross et al. Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela. BMJ Open, v. 9, p. 1-8, 2019.0959-8138https://www.arca.fiocruz.br/handle/icict/3462610.1136/bmjopen-2018-023401Pfizer Inc. The Brazilian Study of Diabetes Control was funded by Pfizer Inc., Brazil. Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. EDMJ received support from the National Council for Scientific and Technological Development (CNPq).University of California. School of Public Health. Department of Epidemiology. Berkeley, CA, USA.Associação Obras Sociais Irmã Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil / Universidade Federal da Bahia. Escola de Nutrição. Departamento Ciências da Nutrição. Salvador, BA, Brasil.University of California. School of Public Health. Department of Epidemiology. Berkeley, CA, USA.Associação Obras Sociais Irmã Dulce. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Laboratório de Epidemiologia Molecular e Bioestatística. Salvador, BA, Brasil.Examine whether glycaemic control varies according to sex and whether the latter plays a role in modifying factors associated with inadequate glycaemic control in patients with type 2 diabetes (T2D) in Brazil and Venezuela. Design, setting and participants This was a crosssectional, nationwide survey conducted in Brazil and Venezuela from February 2006 to June 2007 to obtain information about glycaemic control and its determinants in patients with diabetes mellitus attending outpatient clinics. Main outcome measures Haemoglobin A1c (HbA1c) level was measured by liquid chromatography, and patients with HbA1c ≥7.0% (53 mmol/mol) were considered to have inadequate glycaemic control. The association of selected variables with glycaemic control was analysed by multivariate linear regression, using HbA1c as the dependent variable. Results A total of 9418 patients with T2D were enrolled in Brazil (n=5692) and in Venezuela (n=3726). They included 6214 (66%) women and 3204 (34%) men. On average, HbA1c levels in women were 0.13 (95% CI 0.03 to 0.24; p=0.015) higher than in men, after adjusting for age, marital status, education, race, country, body mass index, duration of disease, complications, type of healthcare, adherence to diet, adherence to treatment and previous measurement of HbA1c. Sex modified the effect of some factors associated with glycaemic control in patients with T2D in our study, but had no noteworthy effect in others. Conclusions Women with T2D had worse glycaemic control than men. Possible causes for poorer glycaemic control in women compared with men include differences in glucose homeostasis, treatment response and psychological factors. In addition, sex modified factors associated with glycaemic control, suggesting the need to develop specific treatment guidelines for men and women.engBMJ Publishing GroupDiabetes tipo 2Diferenças sexuaisIndice glicêmicoHumanosDiabetes Mellitus, Type 2Sex CharacteristicsGlycemic IndexHumansSex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuelainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/34626/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALDuarte F Sex differences correlates... 2019.pdfDuarte F Sex differences correlates... 2019.pdfapplication/pdf273092https://www.arca.fiocruz.br/bitstream/icict/34626/2/Duarte%20F%20Sex%20differences%20correlates...%202019.pdf170cd2dcbe9e8edfb04f721c7ef5915cMD52TEXTDuarte F Sex differences correlates... 2019.pdf.txtDuarte F Sex differences correlates... 2019.pdf.txtExtracted texttext/plain41934https://www.arca.fiocruz.br/bitstream/icict/34626/3/Duarte%20F%20Sex%20differences%20correlates...%202019.pdf.txt61e80e98ea00957ff641c700b4473a3eMD53icict/346262023-03-15 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| dc.title.pt_BR.fl_str_mv |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| title |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| spellingShingle |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela Duarte, Fernanda Gross Diabetes tipo 2 Diferenças sexuais Indice glicêmico Humanos Diabetes Mellitus, Type 2 Sex Characteristics Glycemic Index Humans |
| title_short |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| title_full |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| title_fullStr |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| title_full_unstemmed |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| title_sort |
Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela |
| author |
Duarte, Fernanda Gross |
| author_facet |
Duarte, Fernanda Gross Moreira, Sandra da Silva Almeida, Maria da Conceição Chagas de Teles, Carlos A de Souza Andrade, Carine de Sousa Reingold, Art L. Moreira Junior, Edson Duarte |
| author_role |
author |
| author2 |
Moreira, Sandra da Silva Almeida, Maria da Conceição Chagas de Teles, Carlos A de Souza Andrade, Carine de Sousa Reingold, Art L. Moreira Junior, Edson Duarte |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Duarte, Fernanda Gross Moreira, Sandra da Silva Almeida, Maria da Conceição Chagas de Teles, Carlos A de Souza Andrade, Carine de Sousa Reingold, Art L. Moreira Junior, Edson Duarte |
| dc.subject.other.pt_BR.fl_str_mv |
Diabetes tipo 2 Diferenças sexuais Indice glicêmico Humanos |
| topic |
Diabetes tipo 2 Diferenças sexuais Indice glicêmico Humanos Diabetes Mellitus, Type 2 Sex Characteristics Glycemic Index Humans |
| dc.subject.en.pt_BR.fl_str_mv |
Diabetes Mellitus, Type 2 Sex Characteristics Glycemic Index Humans |
| description |
Pfizer Inc. The Brazilian Study of Diabetes Control was funded by Pfizer Inc., Brazil. Coordination for the Improvement of Higher Education Personnel (CAPES), Brazilian Ministry of Education. EDMJ received support from the National Council for Scientific and Technological Development (CNPq). |
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2019 |
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2019-08-06T16:36:12Z |
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2019-08-06T16:36:12Z |
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2019 |
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DUARTE, Fernanda Gross et al. Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela. BMJ Open, v. 9, p. 1-8, 2019. |
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https://www.arca.fiocruz.br/handle/icict/34626 |
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0959-8138 |
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10.1136/bmjopen-2018-023401 |
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DUARTE, Fernanda Gross et al. Sex differences and correlates of poor glycaemic control in type 2 diabetes: a cross-sectional study in Brazil and Venezuela. BMJ Open, v. 9, p. 1-8, 2019. 0959-8138 10.1136/bmjopen-2018-023401 |
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