Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/3829 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil. |
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Gadelha, Sandra RochaShindo, NiceCruz, José Napoleão MonteMorgado, Mariza GonçalvesCastro Filho, Bernardo Galvão2012-03-29T21:21:11Z2012-03-29T21:21:11Z2003GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003.0074-0276https://www.arca.fiocruz.br/handle/icict/3829engMolecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Laboratório Central de Saúde Pública. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B. In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.Human Immunodeficiency VirusMolecular EpidemiologyDNA ViralGenes EnvGenes GagInfecções por HIVHIV-1AdolescenteVariação GenéticaHumanosPrevalênciaMeia-Idadeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALGadelha SR Molecular epidemiology of human....pdfGadelha SR Molecular epidemiology of human....pdfapplication/pdf579040https://www.arca.fiocruz.br/bitstream/icict/3829/1/Gadelha%20SR%20Molecular%20epidemiology%20of%20human....pdfe145fb2842117dd88d94252adfd4ced4MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/3829/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTGadelha SR Molecular epidemiology of human....pdf.txtGadelha SR Molecular epidemiology of human....pdf.txtExtracted texttext/plain13849https://www.arca.fiocruz.br/bitstream/icict/3829/5/Gadelha%20SR%20Molecular%20epidemiology%20of%20human....pdf.txta6702a3571748ac76535cf981db47568MD55THUMBNAILGadelha SR Molecular epidemiology of human....pdf.jpgGadelha SR Molecular epidemiology of human....pdf.jpgGenerated Thumbnailimage/jpeg2313https://www.arca.fiocruz.br/bitstream/icict/3829/4/Gadelha%20SR%20Molecular%20epidemiology%20of%20human....pdf.jpgadbff948c6f47cb01f1c45d488c05c5eMD54icict/38292023-03-15 14:33:24.333oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:24Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
title |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
spellingShingle |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil Gadelha, Sandra Rocha Human Immunodeficiency Virus Molecular Epidemiology DNA Viral Genes Env Genes Gag Infecções por HIV HIV-1 Adolescente Variação Genética Humanos Prevalência Meia-Idade |
title_short |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
title_full |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
title_fullStr |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
title_full_unstemmed |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
title_sort |
Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil |
author |
Gadelha, Sandra Rocha |
author_facet |
Gadelha, Sandra Rocha Shindo, Nice Cruz, José Napoleão Monte Morgado, Mariza Gonçalves Castro Filho, Bernardo Galvão |
author_role |
author |
author2 |
Shindo, Nice Cruz, José Napoleão Monte Morgado, Mariza Gonçalves Castro Filho, Bernardo Galvão |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Gadelha, Sandra Rocha Shindo, Nice Cruz, José Napoleão Monte Morgado, Mariza Gonçalves Castro Filho, Bernardo Galvão |
dc.subject.en.pt_BR.fl_str_mv |
Human Immunodeficiency Virus Molecular Epidemiology |
topic |
Human Immunodeficiency Virus Molecular Epidemiology DNA Viral Genes Env Genes Gag Infecções por HIV HIV-1 Adolescente Variação Genética Humanos Prevalência Meia-Idade |
dc.subject.decs.pt_BR.fl_str_mv |
DNA Viral Genes Env Genes Gag Infecções por HIV HIV-1 Adolescente Variação Genética Humanos Prevalência Meia-Idade |
description |
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil. |
publishDate |
2003 |
dc.date.issued.fl_str_mv |
2003 |
dc.date.accessioned.fl_str_mv |
2012-03-29T21:21:11Z |
dc.date.available.fl_str_mv |
2012-03-29T21:21:11Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/3829 |
dc.identifier.issn.none.fl_str_mv |
0074-0276 |
identifier_str_mv |
GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003. 0074-0276 |
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