Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil

Detalhes bibliográficos
Autor(a) principal: Gadelha,Sandra Rocha
Data de Publicação: 2003
Outros Autores: Shindo,Nice, Cruz,José Napoleão Monte, Morgado,Mariza Gonçalves, Galvão-Castro,Bernardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400005
Resumo: We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B.In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.
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spelling Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazilhuman immunodeficiency virusmolecular epidemiologyCearáBrazilWe analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B.In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.Instituto Oswaldo Cruz, Ministério da Saúde2003-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400005Memórias do Instituto Oswaldo Cruz v.98 n.4 2003reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762003000400005info:eu-repo/semantics/openAccessGadelha,Sandra RochaShindo,NiceCruz,José Napoleão MonteMorgado,Mariza GonçalvesGalvão-Castro,Bernardoeng2020-04-25T17:49:03Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:11:57.439Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
spellingShingle Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
Gadelha,Sandra Rocha
human immunodeficiency virus
molecular epidemiology
Ceará
Brazil
title_short Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_full Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_fullStr Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_full_unstemmed Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_sort Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
author Gadelha,Sandra Rocha
author_facet Gadelha,Sandra Rocha
Shindo,Nice
Cruz,José Napoleão Monte
Morgado,Mariza Gonçalves
Galvão-Castro,Bernardo
author_role author
author2 Shindo,Nice
Cruz,José Napoleão Monte
Morgado,Mariza Gonçalves
Galvão-Castro,Bernardo
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Gadelha,Sandra Rocha
Shindo,Nice
Cruz,José Napoleão Monte
Morgado,Mariza Gonçalves
Galvão-Castro,Bernardo
dc.subject.por.fl_str_mv human immunodeficiency virus
molecular epidemiology
Ceará
Brazil
topic human immunodeficiency virus
molecular epidemiology
Ceará
Brazil
dc.description.none.fl_txt_mv We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B.In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.
description We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B.In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.
publishDate 2003
dc.date.none.fl_str_mv 2003-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400005
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762003000400005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.98 n.4 2003
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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