Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil

Detalhes bibliográficos
Autor(a) principal: Gadelha, Sandra Rocha
Data de Publicação: 2003
Outros Autores: Shindo, Nice, Cruz, José Napoleão Monte, Morgado, Mariza Gonçalves, Castro Filho, Bernardo Galvão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/3829
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.
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spelling Gadelha, Sandra RochaShindo, NiceCruz, José Napoleão MonteMorgado, Mariza GonçalvesCastro Filho, Bernardo Galvão2012-03-29T21:21:11Z2012-03-29T21:21:11Z2003GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003.0074-0276https://www.arca.fiocruz.br/handle/icict/3829engMolecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.Laboratório Central de Saúde Pública. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.We analyzed, by env and gag heteroduplex mobility assay, 149 human immunodeficiency virus (HIV-1) positive samples collected in Ceará during the year 2000. The prevalence of subtype B was 81.2% and the prevalence of subtype F and B/F recombinants were both 2.7%. Eight (5.4%) and 12 (8%) out of 149 samples showed indeterminate results in the env and gag analysis respectively. By FokI restriction fragment length polymorphism, 34% of the subtype B samples were identified as the typical Brazilian subtype B. In the present study, we identified HIV-1 subtype F and B/F in Ceará for the first time. Our results contribute to the understanding of HIV in Brazil, and may prove useful for the development of vaccine candidates.Human Immunodeficiency VirusMolecular EpidemiologyDNA ViralGenes EnvGenes GagInfecções por HIVHIV-1AdolescenteVariação GenéticaHumanosPrevalênciaMeia-Idadeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALGadelha SR Molecular epidemiology of human....pdfGadelha SR Molecular epidemiology of human....pdfapplication/pdf579040https://www.arca.fiocruz.br/bitstream/icict/3829/1/Gadelha%20SR%20Molecular%20epidemiology%20of%20human....pdfe145fb2842117dd88d94252adfd4ced4MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81648https://www.arca.fiocruz.br/bitstream/icict/3829/2/license.txte095249ac7cacefbfe39684dfe45e706MD52TEXTGadelha SR Molecular epidemiology of human....pdf.txtGadelha SR Molecular epidemiology of human....pdf.txtExtracted texttext/plain13849https://www.arca.fiocruz.br/bitstream/icict/3829/5/Gadelha%20SR%20Molecular%20epidemiology%20of%20human....pdf.txta6702a3571748ac76535cf981db47568MD55THUMBNAILGadelha SR Molecular epidemiology of human....pdf.jpgGadelha SR Molecular epidemiology of human....pdf.jpgGenerated Thumbnailimage/jpeg2313https://www.arca.fiocruz.br/bitstream/icict/3829/4/Gadelha%20SR%20Molecular%20epidemiology%20of%20human....pdf.jpgadbff948c6f47cb01f1c45d488c05c5eMD54icict/38292023-03-15 14:33:24.333oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:24Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
spellingShingle Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
Gadelha, Sandra Rocha
Human Immunodeficiency Virus
Molecular Epidemiology
DNA Viral
Genes Env
Genes Gag
Infecções por HIV
HIV-1
Adolescente
Variação Genética
Humanos
Prevalência
Meia-Idade
title_short Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_full Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_fullStr Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_full_unstemmed Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
title_sort Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil
author Gadelha, Sandra Rocha
author_facet Gadelha, Sandra Rocha
Shindo, Nice
Cruz, José Napoleão Monte
Morgado, Mariza Gonçalves
Castro Filho, Bernardo Galvão
author_role author
author2 Shindo, Nice
Cruz, José Napoleão Monte
Morgado, Mariza Gonçalves
Castro Filho, Bernardo Galvão
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Gadelha, Sandra Rocha
Shindo, Nice
Cruz, José Napoleão Monte
Morgado, Mariza Gonçalves
Castro Filho, Bernardo Galvão
dc.subject.en.pt_BR.fl_str_mv Human Immunodeficiency Virus
Molecular Epidemiology
topic Human Immunodeficiency Virus
Molecular Epidemiology
DNA Viral
Genes Env
Genes Gag
Infecções por HIV
HIV-1
Adolescente
Variação Genética
Humanos
Prevalência
Meia-Idade
dc.subject.decs.pt_BR.fl_str_mv DNA Viral
Genes Env
Genes Gag
Infecções por HIV
HIV-1
Adolescente
Variação Genética
Humanos
Prevalência
Meia-Idade
description Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil.
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2012-03-29T21:21:11Z
dc.date.available.fl_str_mv 2012-03-29T21:21:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/3829
dc.identifier.issn.none.fl_str_mv 0074-0276
identifier_str_mv GADELHA, Sandra Rocha et al. Molecular epidemiology of human immunodeficiency virus-1 in the state of Ceará, Northeast, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 98, n. 4, p. 461-463, jun. 2003.
0074-0276
url https://www.arca.fiocruz.br/handle/icict/3829
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