Induction and modulation of the immune response to Leishmania by Montenegro's skin test.

Detalhes bibliográficos
Autor(a) principal: Nascimento, Maria do Desterro Soares Brandão
Data de Publicação: 1993
Outros Autores: Neves, Neuza Maria Alcântara, Muniz, Maria Edna B, Pinheiro, Samia Feitoza Nunes, Silva, Moacir Paranhos, Pontes-de-Carvalho, Lain Carlos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8337
Resumo: Universidade Federal do Maranhão. Departamento de Patologia. São Luis, MA, Brasil
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spelling Nascimento, Maria do Desterro Soares BrandãoNeves, Neuza Maria AlcântaraMuniz, Maria Edna BPinheiro, Samia Feitoza NunesSilva, Moacir ParanhosPontes-de-Carvalho, Lain Carlos2014-09-09T18:31:41Z2014-09-09T18:31:41Z1993NASCIMENTO, M. D. S. B. et al. Induction and modulation of the immune response to Leishmania by Montenegro's skin test. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 87, n, 1, p. 91-93, 1993.0035-9203https://www.arca.fiocruz.br/handle/icict/8337engLondon School of Hygiene and Tropical MedicineInduction and modulation of the immune response to Leishmania by Montenegro's skin test.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Maranhão. Departamento de Patologia. São Luis, MA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Departmento de Bioagressao.Salvador, BA, Brasil / Laboratório Central do Estado da Bahia. Salvador, BA, BrasilUniversidade Federal do Maranhão. Departamento de Patologia. São Luis, MA, BrasilUniversidade Federal do Maranhão. Departamento de Patologia. São Luis, MA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Departmento de Bioagressao.Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, BrasilThe intradermal inoculation in naive or in previously sensitized individuals of small amounts of Leishmania extract (Montenegro's skin test) induced or modulated, respectively, the immune response to Leishmania, as assessed by subsequent Montenegro's skin tests. These phenomena could hinder the interpretation of Montenegro's skin tests in a population already subjected to the test in the past and, in addition, could affect in an unknown way the development of mucosal lesions in people infected with L. braziliensis or L. amazonensis, since those lesions have been associated with hypersensitivity to Leishmania antigens. Anti-Leishmania antibody responses, assessed by enzyme-linked immunosorbent assay, were not induced in naive individuals by Montenegro's skin tests, but tended to become more intense following these tests in previously sensitized individualsAnticorpos Antiprotozoários/imunologiaLeishmania braziliensis/imunologiaAnimaisFormação de AnticorposEnsaio de Imunoadsorção EnzimáticaHumanosTestes ImunológicosLeishmaniose Cutânea/imunologiaPele/imunologiaTestes Cutâneosinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8337/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALNascimento MDSB Induction and....pdfNascimento MDSB Induction and....pdfapplication/pdf369247https://www.arca.fiocruz.br/bitstream/icict/8337/2/Nascimento%20MDSB%20Induction%20and....pdfe23e1fc8f705f51205f868ce66d02603MD52TEXTNascimento MDSB Induction and....pdf.txtNascimento MDSB Induction and....pdf.txtExtracted texttext/plain16594https://www.arca.fiocruz.br/bitstream/icict/8337/3/Nascimento%20MDSB%20Induction%20and....pdf.txtc39530e9b360dd6d956365310c407303MD53icict/83372023-03-15 14:33:23.321oai:www.arca.fiocruz.br:icict/8337TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGNvbmNvcmRhciBlIGFjZWl0YXIgZXN0YSBsaWNlbsOnYSB2b2PDqiAoYXV0b3Igb3UgZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzKToKCmEpIERlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zDrXRpY2EgZGUgY29weXJpZ2h0IGRhIGVkaXRvcmEgZG8gc2V1IGRvY3VtZW50by4KCmIpIERlY2xhcmEgcXVlIGNvbmhlY2UgZSBhY2VpdGEgYXMgRGlyZXRyaXplcyBwYXJhIG8gUmVwb3NpdMOzcmlvIEluc3RpdHVjaW9uYWwgZGEgRnVuZGHDp8OjbyBPc3dhbGRvIENydXogKEZJT0NSVVopLgoKYykgQ29uY2VkZSDDoCBGSU9DUlVaIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSBhcnF1aXZhciwgcmVwcm9kdXppciwgY29udmVydGVyIChjb21vIGRlZmluaWRvIGEgc2VndWlyKSwgY29tdW5pY2FyCiAKZS9vdSBkaXN0cmlidWlyIG5vIFJlcG9zaXTDs3JpbyBkYSBGSU9DUlVaLCBvIGRvY3VtZW50byBlbnRyZWd1ZSAoaW5jbHVpbmRvIG8gcmVzdW1vL2Fic3RyYWN0KSBlbSBmb3JtYXRvIGRpZ2l0YWwgb3UgCgpwb3IgcXVhbHF1ZXIgb3V0cm8gbWVpby4KCmQpIERlY2xhcmEgcXVlIGF1dG9yaXphIGEgRklPQ1JVWiBhIGFycXVpdmFyIG1haXMgZGUgdW1hIGPDs3BpYSBkZXN0ZSBkb2N1bWVudG8gZSBjb252ZXJ0w6otbG8sIHNlbSBhbHRlcmFyIG8gc2V1IGNvbnRlw7pkbywgCgpwYXJhIHF1YWxxdWVyIGZvcm1hdG8gZGUgYXJxdWl2bywgbWVpbyBvdSBzdXBvcnRlLCBwYXJhIGVmZWl0b3MgZGUgc2VndXJhbsOnYSwgcHJlc2VydmHDp8OjbyAoYmFja3VwKSBlIGFjZXNzby4KCmUpIERlY2xhcmEgcXVlIG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyDDqSBvIHNldSB0cmFiYWxobyBvcmlnaW5hbCwgZSBxdWUgZGV0w6ltIG8gZGlyZWl0byBkZSBjb25jZWRlciBhIHRlcmNlaXJvcyBvcyBkaXJlaXRvcyAKCmNvbnRpZG9zIG5lc3RhIGxpY2Vuw6dhLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGEgZW50cmVnYSBkbyBkb2N1bWVudG8gbsOjbyBpbmZyaW5nZSBvcyBkaXJlaXRvcyBkZSBxdWFscXVlciBvdXRyYSBwZXNzb2Egb3UgZW50aWRhZGUuCgpmKSBEZWNsYXJhIHF1ZSwgbm8gY2FzbyBkbyBkb2N1bWVudG8gc3VibWV0aWRvIGNvbnRlciBtYXRlcmlhbCBkbyBxdWFsIG7Do28gZGV0w6ltIG9zIGRpcmVpdG9zIGRlIGF1dG9yLCBvYnRldmUgYSBhdXRvcml6YcOnw6NvIAoKaXJyZXN0cml0YSBkbyByZXNwZWN0aXZvIGRldGVudG9yIGRlc3NlcyBkaXJlaXRvcywgcGFyYSBjZWRlciBhIEZJT0NSVVogb3MgZGlyZWl0b3MgcmVxdWVyaWRvcyBwb3IgZXN0YSBMaWNlbsOnYSBlIGF1dG9yaXphciBhIAoKdXRpbGl6w6EtbG9zIGxlZ2FsbWVudGUuIERlY2xhcmEgdGFtYsOpbSBxdWUgZXNzZSBtYXRlcmlhbCBjdWpvcyBkaXJlaXRvcyBzw6NvIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlIGlkZW50aWZpY2FkbyBlIHJlY29uaGVjaWRvIAoKbm8gdGV4dG8gb3UgY29udGXDumRvIGRvIGRvY3VtZW50byBlbnRyZWd1ZS4KCmcpIFNFIE8gRE9DVU1FTlRPIEVOVFJFR1VFIMOJIEJBU0VBRE8gRU0gVFJBQkFMSE8gRklOQU5DSUFETyBPVSBBUE9JQURPIFBPUiBPVVRSQSBJTlNUSVRVScOHw4NPIFFVRSBOw4NPIEEgRklPQ1JVWiwgREVDTEFSQSBRVUUgQ1VNUFJJVSAKClFVQUlTUVVFUiBPQlJJR0HDh8OVRVMgRVhJR0lEQVMgUEVMTyBSRVNQRUNUSVZPIENPTlRSQVRPIE9VIEFDT1JETy4gQSBGSU9DUlVaIGlkZW50aWZpY2Fyw6EgY2xhcmFtZW50ZSBvKHMpIG5vbWUocykgZG8ocykgYXV0b3IoZXMpIGRvcyAKCmRpcmVpdG9zIGRvIGRvY3VtZW50byBlbnRyZWd1ZSBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIHBhcmEgYWzDqW0gZG8gcHJldmlzdG8gbmEgYWzDrW5lYSBjKS4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:23Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
title Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
spellingShingle Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
Nascimento, Maria do Desterro Soares Brandão
Anticorpos Antiprotozoários/imunologia
Leishmania braziliensis/imunologia
Animais
Formação de Anticorpos
Ensaio de Imunoadsorção Enzimática
Humanos
Testes Imunológicos
Leishmaniose Cutânea/imunologia
Pele/imunologia
Testes Cutâneos
title_short Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
title_full Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
title_fullStr Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
title_full_unstemmed Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
title_sort Induction and modulation of the immune response to Leishmania by Montenegro's skin test.
author Nascimento, Maria do Desterro Soares Brandão
author_facet Nascimento, Maria do Desterro Soares Brandão
Neves, Neuza Maria Alcântara
Muniz, Maria Edna B
Pinheiro, Samia Feitoza Nunes
Silva, Moacir Paranhos
Pontes-de-Carvalho, Lain Carlos
author_role author
author2 Neves, Neuza Maria Alcântara
Muniz, Maria Edna B
Pinheiro, Samia Feitoza Nunes
Silva, Moacir Paranhos
Pontes-de-Carvalho, Lain Carlos
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Nascimento, Maria do Desterro Soares Brandão
Neves, Neuza Maria Alcântara
Muniz, Maria Edna B
Pinheiro, Samia Feitoza Nunes
Silva, Moacir Paranhos
Pontes-de-Carvalho, Lain Carlos
dc.subject.decs.pt_BR.fl_str_mv Anticorpos Antiprotozoários/imunologia
Leishmania braziliensis/imunologia
Animais
Formação de Anticorpos
Ensaio de Imunoadsorção Enzimática
Humanos
Testes Imunológicos
Leishmaniose Cutânea/imunologia
Pele/imunologia
Testes Cutâneos
topic Anticorpos Antiprotozoários/imunologia
Leishmania braziliensis/imunologia
Animais
Formação de Anticorpos
Ensaio de Imunoadsorção Enzimática
Humanos
Testes Imunológicos
Leishmaniose Cutânea/imunologia
Pele/imunologia
Testes Cutâneos
description Universidade Federal do Maranhão. Departamento de Patologia. São Luis, MA, Brasil
publishDate 1993
dc.date.issued.fl_str_mv 1993
dc.date.accessioned.fl_str_mv 2014-09-09T18:31:41Z
dc.date.available.fl_str_mv 2014-09-09T18:31:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv NASCIMENTO, M. D. S. B. et al. Induction and modulation of the immune response to Leishmania by Montenegro's skin test. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 87, n, 1, p. 91-93, 1993.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8337
dc.identifier.issn.none.fl_str_mv 0035-9203
identifier_str_mv NASCIMENTO, M. D. S. B. et al. Induction and modulation of the immune response to Leishmania by Montenegro's skin test. Transactions of the Royal Society of Tropical Medicine and Hygiene, v. 87, n, 1, p. 91-93, 1993.
0035-9203
url https://www.arca.fiocruz.br/handle/icict/8337
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dc.publisher.none.fl_str_mv London School of Hygiene and Tropical Medicine
publisher.none.fl_str_mv London School of Hygiene and Tropical Medicine
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