Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil

Detalhes bibliográficos
Autor(a) principal: Brito, Luiz Paulo
Data de Publicação: 2018
Outros Autores: Carrara, Luana, Freitas, Rafael Maciel de, Lima, José Bento Pereira, Martins, Ademir J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31561
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.
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spelling Brito, Luiz PauloCarrara, LuanaFreitas, Rafael Maciel deLima, José Bento PereiraMartins, Ademir J.2019-02-12T12:01:44Z2019-02-12T12:01:44Z2018BRITO, Luiz Paulo; et al. Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil. BioMed Research International, Volume 2018, Article ID 2410819, 10p, July 2018.2314-6133https://www.arca.fiocruz.br/handle/icict/3156110.1155/2018/24108192314-6141engHindawi Publishing CorporationAedes aegyptiNíveis de resistênciaPiretróidekdr AlelosRio de JaneiroAedes aegyptiPyrethroidkdr AllelesRio de JaneiroResistanceLevels of ResistanceLevels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.Several mutations in voltage gated sodium channel (NaV) have been identified in Aedes aegypti populations worldwide. However, only few are related to knockdown resistance to pyrethroids, most of which with variations in the 1016 and 1534 NaV sites. In Brazil, at least two Na V alleles are known: NaVR1, with a substitution in the 1534 (1016 Val+ + 1534 Ile kdr ) and NaVR2, with substitutions in both 1016 and sites (1016Ilekdr + 1534Cys kdr ). There is also the duplication in the Na V gene, with one copy carrying the substitution Ile1011Met, although its effects on pyrethroid resistance remain to be clarified. Our goals in this study were (1) to determine the role of each kdr NaV allele and the duplication on pyrethroid resistance and (2) to screen the frequency of the kdr alleles in 27 several natural Ae. aegypti populations from the metropolitan region of Rio de Janeiro.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31561/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALLuizPaulo_brito_etal_IOC_2018.pdfLuizPaulo_brito_etal_IOC_2018.pdfapplication/pdf3435299https://www.arca.fiocruz.br/bitstream/icict/31561/2/LuizPaulo_brito_etal_IOC_2018.pdff1d68664e747f730b260b0966e24314fMD52TEXTLuizPaulo_brito_etal_IOC_2018.pdf.txtLuizPaulo_brito_etal_IOC_2018.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
title Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
spellingShingle Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
Brito, Luiz Paulo
Aedes aegypti
Níveis de resistência
Piretróide
kdr Alelos
Rio de Janeiro
Aedes aegypti
Pyrethroid
kdr Alleles
Rio de Janeiro
Resistance
Levels of Resistance
title_short Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
title_full Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
title_fullStr Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
title_full_unstemmed Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
title_sort Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil
author Brito, Luiz Paulo
author_facet Brito, Luiz Paulo
Carrara, Luana
Freitas, Rafael Maciel de
Lima, José Bento Pereira
Martins, Ademir J.
author_role author
author2 Carrara, Luana
Freitas, Rafael Maciel de
Lima, José Bento Pereira
Martins, Ademir J.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Brito, Luiz Paulo
Carrara, Luana
Freitas, Rafael Maciel de
Lima, José Bento Pereira
Martins, Ademir J.
dc.subject.other.pt_BR.fl_str_mv Aedes aegypti
Níveis de resistência
Piretróide
kdr Alelos
Rio de Janeiro
topic Aedes aegypti
Níveis de resistência
Piretróide
kdr Alelos
Rio de Janeiro
Aedes aegypti
Pyrethroid
kdr Alleles
Rio de Janeiro
Resistance
Levels of Resistance
dc.subject.en.pt_BR.fl_str_mv Aedes aegypti
Pyrethroid
kdr Alleles
Rio de Janeiro
Resistance
Levels of Resistance
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Fisiologia e Controle de Artrópodes Vetores. Rio de Janeiro, RJ. Brasil / Instituto de Biologia do Exército. Laboratório de Entomologia. Rio de Janeiro, RJ, Brasil.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-12T12:01:44Z
dc.date.available.fl_str_mv 2019-02-12T12:01:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BRITO, Luiz Paulo; et al. Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil. BioMed Research International, Volume 2018, Article ID 2410819, 10p, July 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31561
dc.identifier.issn.pt_BR.fl_str_mv 2314-6133
dc.identifier.doi.none.fl_str_mv 10.1155/2018/2410819
dc.identifier.eissn.none.fl_str_mv 2314-6141
identifier_str_mv BRITO, Luiz Paulo; et al. Levels of Resistance to Pyrethroid among Distinct kdr Alleles in Aedes aegypti Laboratory Lines and Frequency of kdr Alleles in 27 Natural Populations from Rio de Janeiro, Brazil. BioMed Research International, Volume 2018, Article ID 2410819, 10p, July 2018.
2314-6133
10.1155/2018/2410819
2314-6141
url https://www.arca.fiocruz.br/handle/icict/31561
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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