Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.

Detalhes bibliográficos
Autor(a) principal: Vilela, Deyla Duarte Carneiro
Data de Publicação: 2012
Outros Autores: Chamusca, Flávia Villela, Andrade, Jorge Clarêncio de Souza, Vallve, Maria de Lourdes Farre, Gonzalez, Ana Cristina, Andrade, Zilton de Araújo, Medrado, Alena Ribeiro Alves Peixoto, Reis, Sílvia Regina de Almeida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: dx.doi.org/10.1016/j.jphotobiol.2012.05.018
Texto Completo: https://www.arca.fiocruz.br/handle/icict/8907
Resumo: Escola Bahiana de Medicina e Saúde Pública. Dentistry Course. Salvador, BA, Brasil
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spelling Vilela, Deyla Duarte CarneiroChamusca, Flávia VillelaAndrade, Jorge Clarêncio de SouzaVallve, Maria de Lourdes FarreGonzalez, Ana CristinaAndrade, Zilton de AraújoMedrado, Alena Ribeiro Alves PeixotoReis, Sílvia Regina de Almeida2014-11-18T19:17:02Z2014-11-18T19:17:02Z2012VILELA, D. D. C. et al. Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation. Journal of Photochemistry and Photobiology: Biology, v. 116, p. 114-120, 2012.1873-2682https://www.arca.fiocruz.br/handle/icict/8907dx.doi.org/10.1016/j.jphotobiol.2012.05.018engElsevierInfluence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleEscola Bahiana de Medicina e Saúde Pública. Dentistry Course. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Dentistry Course. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório de Patologia Experimental. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Dentistry Course. Salvador, BA, BrasilEscola Bahiana de Medicina e Saúde Pública. Dentistry Course. Salvador, BA, BrasilThis study evaluated the influence of hypothalamic–pituitary–adrenal (HPA) axis in cutaneous wounds subjected to laser biomodulation. A total of 48 rats were divided into two groups: Group I (GI) with 24 adrenalectomized animals and Group II (GII) with 24 non-adrenalectomized animals. Each group was divided into two subgroups: the irradiated subgroup which laser was applied to four points at the edges of the wound (670 nm laser, 9 mW) and control subgroup. Rats in each subgroup were sacrificed at 24 or 72 h. Adrenal glands were only removed from GI rats. Three days after adrenalectomy, a cutaneous wound was made. An immunohistochemical analysis was performed using anti-CD45 and anti-CD8 antibodies. Flow cytometry was used to count T lymphocytes and their subpopulations in blood. Decreases in the number of CD45-positive inflammatory cells and in the total numbers of CD8- and CD45-positive cells were observed in histological sections of adrenalectomized animals subjected to laser biomodulation at 24 h. Similar results were observed for distribution of total lymphocytes in blood (p < 0.05). The action of 670 nm laser does not depend exclusively on HPA axis. It is believed that corticosteroid-promoting enzymes liberated in non-adrenal tissues may influence immune response under the influence of this type of phototherapy.Low-intensity laser therapyCD8CD45CD4T lymphocytesGlândulas Suprarrenais/fisiopatologiaSistema Hipotálamo-Hipofisário/fisiopatologiaTerapia a LaserPele/lesõesPele/fisiopatologiaGlândulas Suprarrenais/cirurgiaAdrenalectomia/efeitos adversosAnimaisLinfócitos T CD4-Positivos/citologiaLinfócitos T CD8-Positivos/citologiaInflamação/sangueInflamação/imunologiaInflamação/cirurgiaMasculinoRatosRatos WistarPele/imunologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/8907/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALVilela DDC Influence....pdfVilela DDC Influence....pdfapplication/pdf819305https://www.arca.fiocruz.br/bitstream/icict/8907/2/Vilela%20DDC%20Influence....pdf0c3ef00eb86b487cc7a560d8bc7b30b9MD52TEXTVilela DDC Influence....pdf.txtVilela DDC Influence....pdf.txtExtracted texttext/plain39634https://www.arca.fiocruz.br/bitstream/icict/8907/3/Vilela%20DDC%20Influence....pdf.txt18952ad812414f014e35ee6b87b8a9baMD53icict/89072023-03-15 14:33:04.134oai:www.arca.fiocruz.br:icict/8907TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkFvIGNvbmNvcmRhciBlIGFjZWl0YXIgZXN0YSBsaWNlbsOnYSB2b2PDqiAoYXV0b3Igb3UgZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzKToKCmEpIERlY2xhcmEgcXVlIGNvbmhlY2UgYSBwb2zDrXRpY2EgZGUgY29weXJpZ2h0IGRhIGVkaXRvcmEgZG8gc2V1IGRvY3VtZW50by4KCmIpIERlY2xhcmEgcXVlIGNvbmhlY2UgZSBhY2VpdGEgYXMgRGlyZXRyaXplcyBwYXJhIG8gUmVwb3NpdMOzcmlvIEluc3RpdHVjaW9uYWwgZGEgRnVuZGHDp8OjbyBPc3dhbGRvIENydXogKEZJT0NSVVopLgoKYykgQ29uY2VkZSDDoCBGSU9DUlVaIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSBhcnF1aXZhciwgcmVwcm9kdXppciwgY29udmVydGVyIChjb21vIGRlZmluaWRvIGEgc2VndWlyKSwgY29tdW5pY2FyCiAKZS9vdSBkaXN0cmlidWlyIG5vIFJlcG9zaXTDs3JpbyBkYSBGSU9DUlVaLCBvIGRvY3VtZW50byBlbnRyZWd1ZSAoaW5jbHVpbmRvIG8gcmVzdW1vL2Fic3RyYWN0KSBlbSBmb3JtYXRvIGRpZ2l0YWwgb3UgCgpwb3IgcXVhbHF1ZXIgb3V0cm8gbWVpby4KCmQpIERlY2xhcmEgcXVlIGF1dG9yaXphIGEgRklPQ1JVWiBhIGFycXVpdmFyIG1haXMgZGUgdW1hIGPDs3BpYSBkZXN0ZSBkb2N1bWVudG8gZSBjb252ZXJ0w6otbG8sIHNlbSBhbHRlcmFyIG8gc2V1IGNvbnRlw7pkbywgCgpwYXJhIHF1YWxxdWVyIGZvcm1hdG8gZGUgYXJxdWl2bywgbWVpbyBvdSBzdXBvcnRlLCBwYXJhIGVmZWl0b3MgZGUgc2VndXJhbsOnYSwgcHJlc2VydmHDp8OjbyAoYmFja3VwKSBlIGFjZXNzby4KCmUpIERlY2xhcmEgcXVlIG8gZG9jdW1lbnRvIHN1Ym1ldGlkbyDDqSBvIHNldSB0cmFiYWxobyBvcmlnaW5hbCwgZSBxdWUgZGV0w6ltIG8gZGlyZWl0byBkZSBjb25jZWRlciBhIHRlcmNlaXJvcyBvcyBkaXJlaXRvcyAKCmNvbnRpZG9zIG5lc3RhIGxpY2Vuw6dhLiBEZWNsYXJhIHRhbWLDqW0gcXVlIGEgZW50cmVnYSBkbyBkb2N1bWVudG8gbsOjbyBpbmZyaW5nZSBvcyBkaXJlaXRvcyBkZSBxdWFscXVlciBvdXRyYSBwZXNzb2Egb3UgZW50aWRhZGUuCgpmKSBEZWNsYXJhIHF1ZSwgbm8gY2FzbyBkbyBkb2N1bWVudG8gc3VibWV0aWRvIGNvbnRlciBtYXRlcmlhbCBkbyBxdWFsIG7Do28gZGV0w6ltIG9zIGRpcmVpdG9zIGRlIGF1dG9yLCBvYnRldmUgYSBhdXRvcml6YcOnw6NvIAoKaXJyZXN0cml0YSBkbyByZXNwZWN0aXZvIGRldGVudG9yIGRlc3NlcyBkaXJlaXRvcywgcGFyYSBjZWRlciBhIEZJT0NSVVogb3MgZGlyZWl0b3MgcmVxdWVyaWRvcyBwb3IgZXN0YSBMaWNlbsOnYSBlIGF1dG9yaXphciBhIAoKdXRpbGl6w6EtbG9zIGxlZ2FsbWVudGUuIERlY2xhcmEgdGFtYsOpbSBxdWUgZXNzZSBtYXRlcmlhbCBjdWpvcyBkaXJlaXRvcyBzw6NvIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlIGlkZW50aWZpY2FkbyBlIHJlY29uaGVjaWRvIAoKbm8gdGV4dG8gb3UgY29udGXDumRvIGRvIGRvY3VtZW50byBlbnRyZWd1ZS4KCmcpIFNFIE8gRE9DVU1FTlRPIEVOVFJFR1VFIMOJIEJBU0VBRE8gRU0gVFJBQkFMSE8gRklOQU5DSUFETyBPVSBBUE9JQURPIFBPUiBPVVRSQSBJTlNUSVRVScOHw4NPIFFVRSBOw4NPIEEgRklPQ1JVWiwgREVDTEFSQSBRVUUgQ1VNUFJJVSAKClFVQUlTUVVFUiBPQlJJR0HDh8OVRVMgRVhJR0lEQVMgUEVMTyBSRVNQRUNUSVZPIENPTlRSQVRPIE9VIEFDT1JETy4gQSBGSU9DUlVaIGlkZW50aWZpY2Fyw6EgY2xhcmFtZW50ZSBvKHMpIG5vbWUocykgZG8ocykgYXV0b3IoZXMpIGRvcyAKCmRpcmVpdG9zIGRvIGRvY3VtZW50byBlbnRyZWd1ZSBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIHBhcmEgYWzDqW0gZG8gcHJldmlzdG8gbmEgYWzDrW5lYSBjKS4KRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:04Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
title Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
spellingShingle Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
Vilela, Deyla Duarte Carneiro
Low-intensity laser therapy
CD8
CD45
CD4
T lymphocytes
Glândulas Suprarrenais/fisiopatologia
Sistema Hipotálamo-Hipofisário/fisiopatologia
Terapia a Laser
Pele/lesões
Pele/fisiopatologia
Glândulas Suprarrenais/cirurgia
Adrenalectomia/efeitos adversos
Animais
Linfócitos T CD4-Positivos/citologia
Linfócitos T CD8-Positivos/citologia
Inflamação/sangue
Inflamação/imunologia
Inflamação/cirurgia
Masculino
Ratos
Ratos Wistar
Pele/imunologia
title_short Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
title_full Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
title_fullStr Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
title_full_unstemmed Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
title_sort Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation.
author Vilela, Deyla Duarte Carneiro
author_facet Vilela, Deyla Duarte Carneiro
Chamusca, Flávia Villela
Andrade, Jorge Clarêncio de Souza
Vallve, Maria de Lourdes Farre
Gonzalez, Ana Cristina
Andrade, Zilton de Araújo
Medrado, Alena Ribeiro Alves Peixoto
Reis, Sílvia Regina de Almeida
author_role author
author2 Chamusca, Flávia Villela
Andrade, Jorge Clarêncio de Souza
Vallve, Maria de Lourdes Farre
Gonzalez, Ana Cristina
Andrade, Zilton de Araújo
Medrado, Alena Ribeiro Alves Peixoto
Reis, Sílvia Regina de Almeida
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vilela, Deyla Duarte Carneiro
Chamusca, Flávia Villela
Andrade, Jorge Clarêncio de Souza
Vallve, Maria de Lourdes Farre
Gonzalez, Ana Cristina
Andrade, Zilton de Araújo
Medrado, Alena Ribeiro Alves Peixoto
Reis, Sílvia Regina de Almeida
dc.subject.en.pt_BR.fl_str_mv Low-intensity laser therapy
CD8
CD45
CD4
T lymphocytes
topic Low-intensity laser therapy
CD8
CD45
CD4
T lymphocytes
Glândulas Suprarrenais/fisiopatologia
Sistema Hipotálamo-Hipofisário/fisiopatologia
Terapia a Laser
Pele/lesões
Pele/fisiopatologia
Glândulas Suprarrenais/cirurgia
Adrenalectomia/efeitos adversos
Animais
Linfócitos T CD4-Positivos/citologia
Linfócitos T CD8-Positivos/citologia
Inflamação/sangue
Inflamação/imunologia
Inflamação/cirurgia
Masculino
Ratos
Ratos Wistar
Pele/imunologia
dc.subject.decs.pt_BR.fl_str_mv Glândulas Suprarrenais/fisiopatologia
Sistema Hipotálamo-Hipofisário/fisiopatologia
Terapia a Laser
Pele/lesões
Pele/fisiopatologia
Glândulas Suprarrenais/cirurgia
Adrenalectomia/efeitos adversos
Animais
Linfócitos T CD4-Positivos/citologia
Linfócitos T CD8-Positivos/citologia
Inflamação/sangue
Inflamação/imunologia
Inflamação/cirurgia
Masculino
Ratos
Ratos Wistar
Pele/imunologia
description Escola Bahiana de Medicina e Saúde Pública. Dentistry Course. Salvador, BA, Brasil
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2014-11-18T19:17:02Z
dc.date.available.fl_str_mv 2014-11-18T19:17:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VILELA, D. D. C. et al. Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation. Journal of Photochemistry and Photobiology: Biology, v. 116, p. 114-120, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/8907
dc.identifier.issn.none.fl_str_mv 1873-2682
dc.identifier.doi.none.fl_str_mv dx.doi.org/10.1016/j.jphotobiol.2012.05.018
identifier_str_mv VILELA, D. D. C. et al. Influence of the HPA axis on the inflammatory response in cutaneous wounds with the use of 670-nm laser photobiomodulation. Journal of Photochemistry and Photobiology: Biology, v. 116, p. 114-120, 2012.
1873-2682
dx.doi.org/10.1016/j.jphotobiol.2012.05.018
url https://www.arca.fiocruz.br/handle/icict/8907
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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