Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis

Detalhes bibliográficos
Autor(a) principal: Araújo, Caliandra Pinto
Data de Publicação: 2010
Outros Autores: Gurgel, Clarissa Araújo Silva, Ramos, Eduardo Antônio Gonçalves, Freitas, Valéria Souza, Barbosa Junior, Aryon de Almeida, Ramalho, Luciana Maria Pedreira, Santos, Jean Nunes dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/12968
Resumo: Federal University of Bahia. School of Dentistry. Department of Oral Pathology, Laboratory of Oral Surgical Pathology. Salvador, BA, Brasil
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spelling Araújo, Caliandra PintoGurgel, Clarissa Araújo SilvaRamos, Eduardo Antônio GonçalvesFreitas, Valéria SouzaBarbosa Junior, Aryon de AlmeidaRamalho, Luciana Maria PedreiraSantos, Jean Nunes dos2016-03-03T17:20:58Z2016-03-03T17:20:58Z2010ARAÚJO, C. P. et al. Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis. Journal of Molecular Histology, v. 41, p. 357-365, 2010.1567-2379https://www.arca.fiocruz.br/handle/icict/1296810.1010.1007/s10735-010-9297-z07/s10735-010-9297-zengSpringer VerlagAccumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFederal University of Bahia. School of Dentistry. Department of Oral Pathology, Laboratory of Oral Surgical Pathology. Salvador, BA, BrasilFundação Oswaldo Cruz, Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz, Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilState University of Feira de Santana. Department of Health. Feira de Santana, BA, BrasilFundação Oswaldo Cruz, Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilState University of Feira de Santana. Department of Stomatology. Feira de Santana, BA, BrasilFederal University of Bahia. School of Dentistry. Department of Oral Pathology, Laboratory of Oral Surgical Pathology. Salvador, BA, BrasilLCs and MCs are known to be directly influenced by UV radiation. This study investigated the presence of Langerhans cells (LCs) and mast cells (MCs) in actinic cheilitis (AC) exhibiting epithelial dysplasia (ED). Using immunohistochemistry for CD1a and mast cell tryptase, LCs and MCs density was assessed in 35 cases of AC with different degrees of ED. LCs were found in 32 cases of AC whereas MCs were found in all cases. There was an increase in LCs density irrespective of degree of ED when the cases were compared to normal lip mucosa (P = 0.04343). No statistical difference in LCs density was observed regarding the different degrees of dysplasia (P[0.05). Significant difference in MCs density between mild and moderate dysplasia and normal lip mucosa was found (P\0.05). No significant correlation between LCs and MCs was seen (P = 0.1258). Although no correlation could be established between LCs and MCs and the different degrees of ED; it is possible that the accumulation of LCs plays an immunostimulatory and protective role in the defense against progression of dysplasia. Further studies are necessary to determine the role of MCs in the development of AC.Actinic chelitisLangerhans cellsMast cellsEpithelial dysplasiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/12968/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAraujo CP Accumulation.pdfAraujo CP Accumulation.pdfapplication/pdf959564https://www.arca.fiocruz.br/bitstream/icict/12968/2/Araujo%20CP%20Accumulation.pdff7c2c89a57560280c6aa99453fd193aeMD52TEXTAraujo CP Accumulation.pdf.txtAraujo CP Accumulation.pdf.txtExtracted texttext/plain36376https://www.arca.fiocruz.br/bitstream/icict/12968/3/Araujo%20CP%20Accumulation.pdf.txtd9ee5661990796fd399c99dd1ca12c0eMD53icict/129682023-03-15 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dc.title.pt_BR.fl_str_mv Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
spellingShingle Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
Araújo, Caliandra Pinto
Actinic chelitis
Langerhans cells
Mast cells
Epithelial dysplasia
title_short Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_full Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_fullStr Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_full_unstemmed Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_sort Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
author Araújo, Caliandra Pinto
author_facet Araújo, Caliandra Pinto
Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Junior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
author_role author
author2 Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Junior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Caliandra Pinto
Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Junior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
dc.subject.en.pt_BR.fl_str_mv Actinic chelitis
Langerhans cells
Mast cells
Epithelial dysplasia
topic Actinic chelitis
Langerhans cells
Mast cells
Epithelial dysplasia
description Federal University of Bahia. School of Dentistry. Department of Oral Pathology, Laboratory of Oral Surgical Pathology. Salvador, BA, Brasil
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2016-03-03T17:20:58Z
dc.date.available.fl_str_mv 2016-03-03T17:20:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv ARAÚJO, C. P. et al. Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis. Journal of Molecular Histology, v. 41, p. 357-365, 2010.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/12968
dc.identifier.issn.none.fl_str_mv 1567-2379
dc.identifier.doi.none.fl_str_mv 10.1010.1007/s10735-010-9297-z07/s10735-010-9297-z
identifier_str_mv ARAÚJO, C. P. et al. Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis. Journal of Molecular Histology, v. 41, p. 357-365, 2010.
1567-2379
10.1010.1007/s10735-010-9297-z07/s10735-010-9297-z
url https://www.arca.fiocruz.br/handle/icict/12968
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/12968/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/12968/2/Araujo%20CP%20Accumulation.pdf
https://www.arca.fiocruz.br/bitstream/icict/12968/3/Araujo%20CP%20Accumulation.pdf.txt
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