Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis

Detalhes bibliográficos
Autor(a) principal: Araújo, Caliandra Pinto
Data de Publicação: 2010
Outros Autores: Gurgel, Clarissa Araújo Silva, Ramos, Eduardo Antônio Gonçalves, Freitas, Valéria Souza, Barbosa Júnior, Aryon de Almeida, Ramalho, Luciana Maria Pedreira, Santos, Jean Nunes dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://repositorio.ufba.br/ri/handle/ri/13569
Resumo: Texto completo: acesso restrito. p.357-365
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spelling Araújo, Caliandra PintoGurgel, Clarissa Araújo SilvaRamos, Eduardo Antônio GonçalvesFreitas, Valéria SouzaBarbosa Júnior, Aryon de AlmeidaRamalho, Luciana Maria PedreiraSantos, Jean Nunes dosAraújo, Caliandra PintoGurgel, Clarissa Araújo SilvaRamos, Eduardo Antônio GonçalvesFreitas, Valéria SouzaBarbosa Júnior, Aryon de AlmeidaRamalho, Luciana Maria PedreiraSantos, Jean Nunes dos2013-11-06T20:34:35Z20101567-2379http://repositorio.ufba.br/ri/handle/ri/13569v. 41, n. 6Texto completo: acesso restrito. p.357-365LCs and MCs are known to be directly influenced by UV radiation. This study investigated the presence of Langerhans cells (LCs) and mast cells (MCs) in actinic cheilitis (AC) exhibiting epithelial dysplasia (ED). Using immunohistochemistry for CD1a and mast cell tryptase, LCs and MCs density was assessed in 35 cases of AC with different degrees of ED. LCs were found in 32 cases of AC whereas MCs were found in all cases. There was an increase in LCs density irrespective of degree of ED when the cases were compared to normal lip mucosa (P = 0.04343). No statistical difference in LCs density was observed regarding the different degrees of dysplasia (P > 0.05). Significant difference in MCs density between mild and moderate dysplasia and normal lip mucosa was found (P < 0.05). No significant correlation between LCs and MCs was seen (P = 0.1258). Although no correlation could be established between LCs and MCs and the different degrees of ED; it is possible that the accumulation of LCs plays an immunostimulatory and protective role in the defense against progression of dysplasia. Further studies are necessary to determine the role of MCs in the development of AC.Submitted by Suelen Reis (suziy.ellen@gmail.com) on 2013-06-25T18:20:54Z No. of bitstreams: 1 Caliandra Araujo.pdf: 959564 bytes, checksum: f7c2c89a57560280c6aa99453fd193ae (MD5)Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2013-11-06T20:34:35Z (GMT) No. of bitstreams: 1 Caliandra Araujo.pdf: 959564 bytes, checksum: f7c2c89a57560280c6aa99453fd193ae (MD5)Made available in DSpace on 2013-11-06T20:34:35Z (GMT). No. of bitstreams: 1 Caliandra Araujo.pdf: 959564 bytes, checksum: f7c2c89a57560280c6aa99453fd193ae (MD5) Previous issue date: 2010http://dx.doi.org/10.1007/s10735-010-9297-zreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAActinic chelitisLangerhans cellsMast cellsEpithelial dysplasiaAccumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitisJournal of Molecular Histologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALCaliandra Araujo.pdfCaliandra Araujo.pdfapplication/pdf959564https://repositorio.ufba.br/bitstream/ri/13569/1/Caliandra%20Araujo.pdff7c2c89a57560280c6aa99453fd193aeMD51LICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/13569/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52TEXTCaliandra Araujo.pdf.txtCaliandra Araujo.pdf.txtExtracted texttext/plain36156https://repositorio.ufba.br/bitstream/ri/13569/3/Caliandra%20Araujo.pdf.txt8a8ed958944b812a998544f10e625948MD53ri/135692022-08-08 13:17:32.331oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:32Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
dc.title.alternative.pt_BR.fl_str_mv Journal of Molecular Histology
title Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
spellingShingle Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
Araújo, Caliandra Pinto
Actinic chelitis
Langerhans cells
Mast cells
Epithelial dysplasia
title_short Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_full Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_fullStr Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_full_unstemmed Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
title_sort Accumulation of CD1a-positive Langerhans cells and mast cells in actinic cheilitis
author Araújo, Caliandra Pinto
author_facet Araújo, Caliandra Pinto
Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Júnior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
author_role author
author2 Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Júnior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Araújo, Caliandra Pinto
Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Júnior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
Araújo, Caliandra Pinto
Gurgel, Clarissa Araújo Silva
Ramos, Eduardo Antônio Gonçalves
Freitas, Valéria Souza
Barbosa Júnior, Aryon de Almeida
Ramalho, Luciana Maria Pedreira
Santos, Jean Nunes dos
dc.subject.por.fl_str_mv Actinic chelitis
Langerhans cells
Mast cells
Epithelial dysplasia
topic Actinic chelitis
Langerhans cells
Mast cells
Epithelial dysplasia
description Texto completo: acesso restrito. p.357-365
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2013-11-06T20:34:35Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufba.br/ri/handle/ri/13569
dc.identifier.issn.none.fl_str_mv 1567-2379
dc.identifier.number.pt_BR.fl_str_mv v. 41, n. 6
identifier_str_mv 1567-2379
v. 41, n. 6
url http://repositorio.ufba.br/ri/handle/ri/13569
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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