Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease

Detalhes bibliográficos
Autor(a) principal: Campbell, Bronwyn
Data de Publicação: 2016
Outros Autores: Cortes, Helder, Annoscia, Giada, Giannelli, Alessio, Parisi, Antonio, Latrofa, Maria Stefania, Dantas-Torres, Filipe, Cardoso, Luís, Otranto, Domenico
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/19296
Resumo: Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy.
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spelling Campbell, BronwynCortes, HelderAnnoscia, GiadaGiannelli, AlessioParisi, AntonioLatrofa, Maria StefaniaDantas-Torres, FilipeCardoso, LuísOtranto, Domenico2017-06-05T13:12:25Z2017-06-05T13:12:25Z2016CAMPBELL, B. et al. Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease. Parasites & Vectors, v. 9, n. 1, dez. 2016.1756-3305https://www.arca.fiocruz.br/handle/icict/1929610.1186/s13071-016-1783-zengParamyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversità degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy.Universidade de Évora. Instituto de Ciências Agrárias e Ambientais Mediterrânicas. Victor Caeiro Laboratory of Parasitology. Évora, Portugal.Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy.Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy.IZS Istituto Zooprofilattico Sperimentale Puglia e Basilicata. Putignano, Italy.Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy.Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy / Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Departamento de Imunologia. Recife, PE, Brasil.University of Trás-os-Montes e Alto Douro (UTAD). School of Agrarian and Veterinary Sciences. Department of Veterinary Sciences. Vila Real, Portugal.Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, ItalyOf increasing importance to the medical and veterinary communities is the zoonotic filarioid nematode Onchocerca lupi. Onchocercosis, thus far found in wolves, dogs, cats and humans, is diagnosed via skin snips to detect microfilariae and surgical removal of adults from the eye of the host. These methods are time-consuming, laborious and invasive, highlighting the need for new tools for the diagnosis of O. lupi in susceptible hosts. Symptoms related to the presence of the adults in the eye can range from none apparent to severe, including blindness. No reliable chemotherapeutic protocols are available, as yet, to eliminate the infection. Paramyosin, an invertebrate-specific protein, has been well-studied as an allergen, diagnostic marker and vaccine candidate. The aim of this study, therefore, was to isolate and characterise paramyosin from O. lupi to assess its suitability for the development of a serological diagnostic assay.Onchocerca lupiZoonoticParamyosinBioinformaticsDiagnostic testsVaccineinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/19296/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINAL27604904 2016 cam-par.oa.pdf27604904 2016 cam-par.oa.pdfapplication/pdf2102592https://www.arca.fiocruz.br/bitstream/icict/19296/2/27604904%202016%20cam-par.oa.pdf62a05d2715802c8b6d9a7253e2a531d9MD52TEXT27604904 2016 cam-par.oa.pdf.txt27604904 2016 cam-par.oa.pdf.txtExtracted texttext/plain54252https://www.arca.fiocruz.br/bitstream/icict/19296/3/27604904%202016%20cam-par.oa.pdf.txt9959039b05ce780dcec3f9d82463708cMD53icict/192962019-04-02 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dc.title.pt_BR.fl_str_mv Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
title Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
spellingShingle Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
Campbell, Bronwyn
Onchocerca lupi
Zoonotic
Paramyosin
Bioinformatics
Diagnostic tests
Vaccine
title_short Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
title_full Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
title_fullStr Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
title_full_unstemmed Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
title_sort Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease
author Campbell, Bronwyn
author_facet Campbell, Bronwyn
Cortes, Helder
Annoscia, Giada
Giannelli, Alessio
Parisi, Antonio
Latrofa, Maria Stefania
Dantas-Torres, Filipe
Cardoso, Luís
Otranto, Domenico
author_role author
author2 Cortes, Helder
Annoscia, Giada
Giannelli, Alessio
Parisi, Antonio
Latrofa, Maria Stefania
Dantas-Torres, Filipe
Cardoso, Luís
Otranto, Domenico
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Campbell, Bronwyn
Cortes, Helder
Annoscia, Giada
Giannelli, Alessio
Parisi, Antonio
Latrofa, Maria Stefania
Dantas-Torres, Filipe
Cardoso, Luís
Otranto, Domenico
dc.subject.en.none.fl_str_mv Onchocerca lupi
Zoonotic
Paramyosin
Bioinformatics
Diagnostic tests
Vaccine
topic Onchocerca lupi
Zoonotic
Paramyosin
Bioinformatics
Diagnostic tests
Vaccine
description Università degli Studi di Bari. Dipartimento di Medicina Veterinaria. Valenzano, Bari, Italy.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2017-06-05T13:12:25Z
dc.date.available.fl_str_mv 2017-06-05T13:12:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv CAMPBELL, B. et al. Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease. Parasites & Vectors, v. 9, n. 1, dez. 2016.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/19296
dc.identifier.issn.pt_BR.fl_str_mv 1756-3305
dc.identifier.doi.pt_BR.fl_str_mv 10.1186/s13071-016-1783-z
identifier_str_mv CAMPBELL, B. et al. Paramyosin of canine Onchocerca lupi: usefulness for the diagnosis of a neglected zoonotic disease. Parasites & Vectors, v. 9, n. 1, dez. 2016.
1756-3305
10.1186/s13071-016-1783-z
url https://www.arca.fiocruz.br/handle/icict/19296
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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