Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis

Detalhes bibliográficos
Autor(a) principal: Villar, Livia Melo
Data de Publicação: 2019
Outros Autores: Bezerra, Cristianne Sousa, Cruz, Helena Medina, Portilho, Moyra Machado, Flores, Geane Lopes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/35113
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.
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spelling Villar, Livia MeloBezerra, Cristianne SousaCruz, Helena MedinaPortilho, Moyra MachadoFlores, Geane Lopes2019-08-27T15:58:16Z2019-08-27T15:58:16Z2019VILLAR, Livia Melo et al. Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis. Canadian Journal of Gastroenterology and Hepatology, v. 2019, p. 1-11, 2019.2291-2789https://www.arca.fiocruz.br/handle/icict/3511310.1155/2019/56727952291-2797engHindawi Publishing CorporationVírus da hepatite BFluido oralAplicabilidadeDiagnósticoSangue secoHepatitis B VirusDiagnosisOral fluidDried bloodAplicabilityApplicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Instituto Federal de Educação, Ciência e Tecnologia do Ceará. Campus Fortaleza. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Muniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.Hepatitis B virus (HBV) is one of the major causes of chronic liver disease worldwide; however most of individuals are not aware about the infection. Oral fluid and dried blood spot (DBS) samples may be an alternative to serum to HBV diagnosis to increase the access to diagnosis in remote areas or high-risk groups. The main objective of this review is to give an insight about the usefulness of oral fluid and DBS for detecting HBV markers. Several groups have evaluated the detection of HBsAg, anti-HBc, and anti-HBs markers in oral fluid and DBS samples demonstrating 13 to 100% of sensitivity and specificity according different groups, sample collectors, and diagnosis assays. In the same way, HBV DNA detection using oral fluid and DBS samples demonstrate different values of sensitivity according type of collection, studied group, extraction, and detection methods. Thus, serological and molecular diagnostic tests demonstrated good performance for detecting HBV using oral fluid and DBS according some characteristics and could be useful to increase the access to the diagnosis of HBV.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/35113/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALGeaneFlores_HelenaCruz_etal_IOC_2019.pdfGeaneFlores_HelenaCruz_etal_IOC_2019.pdfapplication/pdf1644866https://www.arca.fiocruz.br/bitstream/icict/35113/2/GeaneFlores_HelenaCruz_etal_IOC_2019.pdfa657dc768b5410107e82a737c8a12990MD52TEXTGeaneFlores_HelenaCruz_etal_IOC_2019.pdf.txtGeaneFlores_HelenaCruz_etal_IOC_2019.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
title Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
spellingShingle Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
Villar, Livia Melo
Vírus da hepatite B
Fluido oral
Aplicabilidade
Diagnóstico
Sangue seco
Hepatitis B Virus
Diagnosis
Oral fluid
Dried blood
Aplicability
title_short Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
title_full Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
title_fullStr Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
title_full_unstemmed Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
title_sort Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis
author Villar, Livia Melo
author_facet Villar, Livia Melo
Bezerra, Cristianne Sousa
Cruz, Helena Medina
Portilho, Moyra Machado
Flores, Geane Lopes
author_role author
author2 Bezerra, Cristianne Sousa
Cruz, Helena Medina
Portilho, Moyra Machado
Flores, Geane Lopes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Villar, Livia Melo
Bezerra, Cristianne Sousa
Cruz, Helena Medina
Portilho, Moyra Machado
Flores, Geane Lopes
dc.subject.other.pt_BR.fl_str_mv Vírus da hepatite B
Fluido oral
Aplicabilidade
Diagnóstico
Sangue seco
topic Vírus da hepatite B
Fluido oral
Aplicabilidade
Diagnóstico
Sangue seco
Hepatitis B Virus
Diagnosis
Oral fluid
Dried blood
Aplicability
dc.subject.en.pt_BR.fl_str_mv Hepatitis B Virus
Diagnosis
Oral fluid
Dried blood
Aplicability
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil.
publishDate 2019
dc.date.accessioned.fl_str_mv 2019-08-27T15:58:16Z
dc.date.available.fl_str_mv 2019-08-27T15:58:16Z
dc.date.issued.fl_str_mv 2019
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VILLAR, Livia Melo et al. Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis. Canadian Journal of Gastroenterology and Hepatology, v. 2019, p. 1-11, 2019.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/35113
dc.identifier.issn.pt_BR.fl_str_mv 2291-2789
dc.identifier.doi.none.fl_str_mv 10.1155/2019/5672795
dc.identifier.eissn.none.fl_str_mv 2291-2797
identifier_str_mv VILLAR, Livia Melo et al. Applicability of Oral Fluid and Dried Blood Spot for Hepatitis B Virus Diagnosis. Canadian Journal of Gastroenterology and Hepatology, v. 2019, p. 1-11, 2019.
2291-2789
10.1155/2019/5672795
2291-2797
url https://www.arca.fiocruz.br/handle/icict/35113
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/35113/2/GeaneFlores_HelenaCruz_etal_IOC_2019.pdf
https://www.arca.fiocruz.br/bitstream/icict/35113/3/GeaneFlores_HelenaCruz_etal_IOC_2019.pdf.txt
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