New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2021 |
| Outros Autores: | , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/46226 |
Resumo: | Secretary of Health Surveillance, Ministry of Health of Brazil. The funders had no role in study design, analysis, decision to publish or preparation of the manuscript. This study was supported by the Intramural Research Program of the Fundação Oswaldo Cruz (Inova FIOCRUZ, grant number: VPPIS-001-FIO18). ESP is funded by the Wellcome Trust (grant number 213589/Z/18/Z). |
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Costa, Larissa CatharinaVeiga, Rafael ValenteOliveira, Juliane FonsecaRodrigues, Moreno S.Andrade, Roberto F. S.Paixão, Enny S.Teixeira, Maria GlóriaCosta, Maria da Conceição N.Cardim, Luciana L.Carmo, Eduardo H.Oliveira, Wanderson K.Gonçalves, José Í. K.Fernandes, Qeren H. R. F.Barreto, Maurício LimaQueiroz, Artur Trancoso Lopo deGräf, Tiago2021-03-01T17:28:46Z2021-03-01T17:28:46Z2021COSTA, Larissa Catharina et al. New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil. Viruses, p. 1-11, 2021.1999-4915https://www.arca.fiocruz.br/handle/icict/4622610.3390/v13010012Secretary of Health Surveillance, Ministry of Health of Brazil. The funders had no role in study design, analysis, decision to publish or preparation of the manuscript. This study was supported by the Intramural Research Program of the Fundação Oswaldo Cruz (Inova FIOCRUZ, grant number: VPPIS-001-FIO18). ESP is funded by the Wellcome Trust (grant number 213589/Z/18/Z).Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Rondônia Fiocruz. Porto Velho, RO, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil / Federal University of Bahia. Physics Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil / London School of Hygiene and Tropical Medicine. Department of Infectious Disease Epidemiology. London, UK.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil / Federal University of Bahia. Collective Health Institute, Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil / Federal University of Bahia. Collective Health Institute, Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil / Federal University of Bahia. Collective Health Institute, Salvador, BA, Brazil.Ministry of Defense Hospital das Armed Forces. Technical Directorate of Education and Research. Brasilia, DF, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil / Federal University of Bahia. Collective Health Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Center of Data and Knowledge Integration for Health (CIDACS). Gonçalo Moniz Institute. Salvador, BA, Brazil.Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brazil.Zika virus (ZIKV) became a worldwide public health emergency after its introduction in the Americas. Brazil was implicated as central in the ZIKV dispersion, however, a better understanding of the pathways the virus took to arrive in Brazil and the dispersion within the country is needed. An updated genome dataset was assembled with publicly available data. Bayesian phylogeography methods were applied to reconstruct the spatiotemporal history of ZIKV in the Americas and with more detail inside Brazil. Our analyses reconstructed the Brazilian state of Pernambuco as the likely point of introduction of ZIKV in Brazil, possibly during the 2013 Confederations Cup. Pernambuco played an important role in spreading the virus to other Brazilian states. Our results also underscore the long cryptic circulation of ZIKV in all analyzed locations in Brazil. Conclusions: This study brings new insights about the early moments of ZIKV in the Americas, especially regarding the Brazil-Haiti cluster at the base of the American clade and describing for the first time migration patterns within Brazil.engMDPIZika virusBrasilFilogeografiaEpidemiasZika virusBrazilPhylogeographyMolecular clockNew Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/46226/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALCosta, Catarina Larissa. New Insights....pdfCosta, Catarina Larissa. 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| dc.title.pt_BR.fl_str_mv |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| title |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| spellingShingle |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil Costa, Larissa Catharina Zika virus Brasil Filogeografia Epidemias Zika virus Brazil Phylogeography Molecular clock |
| title_short |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| title_full |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| title_fullStr |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| title_full_unstemmed |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| title_sort |
New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil |
| author |
Costa, Larissa Catharina |
| author_facet |
Costa, Larissa Catharina Veiga, Rafael Valente Oliveira, Juliane Fonseca Rodrigues, Moreno S. Andrade, Roberto F. S. Paixão, Enny S. Teixeira, Maria Glória Costa, Maria da Conceição N. Cardim, Luciana L. Carmo, Eduardo H. Oliveira, Wanderson K. Gonçalves, José Í. K. Fernandes, Qeren H. R. F. Barreto, Maurício Lima Queiroz, Artur Trancoso Lopo de Gräf, Tiago |
| author_role |
author |
| author2 |
Veiga, Rafael Valente Oliveira, Juliane Fonseca Rodrigues, Moreno S. Andrade, Roberto F. S. Paixão, Enny S. Teixeira, Maria Glória Costa, Maria da Conceição N. Cardim, Luciana L. Carmo, Eduardo H. Oliveira, Wanderson K. Gonçalves, José Í. K. Fernandes, Qeren H. R. F. Barreto, Maurício Lima Queiroz, Artur Trancoso Lopo de Gräf, Tiago |
| author2_role |
author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Costa, Larissa Catharina Veiga, Rafael Valente Oliveira, Juliane Fonseca Rodrigues, Moreno S. Andrade, Roberto F. S. Paixão, Enny S. Teixeira, Maria Glória Costa, Maria da Conceição N. Cardim, Luciana L. Carmo, Eduardo H. Oliveira, Wanderson K. Gonçalves, José Í. K. Fernandes, Qeren H. R. F. Barreto, Maurício Lima Queiroz, Artur Trancoso Lopo de Gräf, Tiago |
| dc.subject.other.pt_BR.fl_str_mv |
Zika virus Brasil Filogeografia Epidemias |
| topic |
Zika virus Brasil Filogeografia Epidemias Zika virus Brazil Phylogeography Molecular clock |
| dc.subject.en.pt_BR.fl_str_mv |
Zika virus Brazil Phylogeography Molecular clock |
| description |
Secretary of Health Surveillance, Ministry of Health of Brazil. The funders had no role in study design, analysis, decision to publish or preparation of the manuscript. This study was supported by the Intramural Research Program of the Fundação Oswaldo Cruz (Inova FIOCRUZ, grant number: VPPIS-001-FIO18). ESP is funded by the Wellcome Trust (grant number 213589/Z/18/Z). |
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2021 |
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2021-03-01T17:28:46Z |
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2021-03-01T17:28:46Z |
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2021 |
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info:eu-repo/semantics/article |
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COSTA, Larissa Catharina et al. New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil. Viruses, p. 1-11, 2021. |
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https://www.arca.fiocruz.br/handle/icict/46226 |
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1999-4915 |
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10.3390/v13010012 |
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COSTA, Larissa Catharina et al. New Insights on the Zika Virus Arrival in the Americas and Spatiotemporal Reconstruction of the Epidemic Dynamics in Brazil. Viruses, p. 1-11, 2021. 1999-4915 10.3390/v13010012 |
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