Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Cassiano Felippe Gonçalves de
Data de Publicação: 2015
Outros Autores: Silva, Adriana Ribeiro, Burth, Patrícia, Faria, Mauro Velho Castro, Faria Neto, Hugo Caire Castro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/12778
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
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spelling Albuquerque, Cassiano Felippe Gonçalves deSilva, Adriana RibeiroBurth, PatríciaFaria, Mauro Velho CastroFaria Neto, Hugo Caire Castro2016-02-22T15:15:50Z2016-02-22T15:15:50Z2015ALBUQUERQUE, Cassiano Felippe Gonçalves de; et al. Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation. Mediators of Inflammation, v.2015, Article ID260465, 9p, 2015.0962-9351https://www.arca.fiocruz.br/handle/icict/1277810.1155/2015/2604651466-1861engHindawi Publishing CorporationAcute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Instituto de Biologia. Departamento de Biologia Celular e Molecular. Niterói, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Faculdade de Ciências Médicas. Departamento de Medicina Interna. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.Lung injury especially acute respiratory distress syndrome (ARDS) can be triggered by diverse stimuli, including fatty acids and microbes. ARDS affects thousands of people worldwide each year, presenting high mortality rate and having an economic impact. One of the hallmarks of lung injury is edema formation with alveoli flooding. Animal models are used to study lung injury. Oleic acid-induced lung injury is a widely used model resembling the human disease. The oleic acid has been linked to metabolic and inflammatory diseases; here we focus on lung injury. Firstly, we briefly discuss ARDS and secondly we address the mechanisms by which oleic acid triggers lung injury and inflammation.Acute Respiratory Distress SyndromeOleic AcidLung InjuryInflammationSíndrome do Desconforto Respiratório do AdultoÁcido OleicoLesão PulmonarInflamaçãoinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/12778/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALcassiano_albuquerque_etal_IOC_2015.pdfcassiano_albuquerque_etal_IOC_2015.pdfapplication/pdf2378904https://www.arca.fiocruz.br/bitstream/icict/12778/2/cassiano_albuquerque_etal_IOC_2015.pdf36787e7d0e6457e85ecc64b7b9ff7a1cMD52TEXTcassiano_albuquerque_etal_IOC_2015.pdf.txtcassiano_albuquerque_etal_IOC_2015.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
title Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
spellingShingle Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
Albuquerque, Cassiano Felippe Gonçalves de
Acute Respiratory Distress Syndrome
Oleic Acid
Lung Injury
Inflammation
Síndrome do Desconforto Respiratório do Adulto
Ácido Oleico
Lesão Pulmonar
Inflamação
title_short Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
title_full Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
title_fullStr Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
title_full_unstemmed Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
title_sort Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation
author Albuquerque, Cassiano Felippe Gonçalves de
author_facet Albuquerque, Cassiano Felippe Gonçalves de
Silva, Adriana Ribeiro
Burth, Patrícia
Faria, Mauro Velho Castro
Faria Neto, Hugo Caire Castro
author_role author
author2 Silva, Adriana Ribeiro
Burth, Patrícia
Faria, Mauro Velho Castro
Faria Neto, Hugo Caire Castro
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Albuquerque, Cassiano Felippe Gonçalves de
Silva, Adriana Ribeiro
Burth, Patrícia
Faria, Mauro Velho Castro
Faria Neto, Hugo Caire Castro
dc.subject.en.pt_BR.fl_str_mv Acute Respiratory Distress Syndrome
Oleic Acid
Lung Injury
Inflammation
topic Acute Respiratory Distress Syndrome
Oleic Acid
Lung Injury
Inflammation
Síndrome do Desconforto Respiratório do Adulto
Ácido Oleico
Lesão Pulmonar
Inflamação
dc.subject.decs.pt_BR.fl_str_mv Síndrome do Desconforto Respiratório do Adulto
Ácido Oleico
Lesão Pulmonar
Inflamação
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2016-02-22T15:15:50Z
dc.date.available.fl_str_mv 2016-02-22T15:15:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv ALBUQUERQUE, Cassiano Felippe Gonçalves de; et al. Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation. Mediators of Inflammation, v.2015, Article ID260465, 9p, 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/12778
dc.identifier.issn.none.fl_str_mv 0962-9351
dc.identifier.doi.none.fl_str_mv 10.1155/2015/260465
dc.identifier.eissn.none.fl_str_mv 1466-1861
identifier_str_mv ALBUQUERQUE, Cassiano Felippe Gonçalves de; et al. Acute Respiratory Distress Syndrome: Role of Oleic Acid-Triggered Lung Injury and Inflammation. Mediators of Inflammation, v.2015, Article ID260465, 9p, 2015.
0962-9351
10.1155/2015/260465
1466-1861
url https://www.arca.fiocruz.br/handle/icict/12778
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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