Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/28807 |
Resumo: | 2020-08-06 |
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Torres, Thiago SHarrison, Linda JLa Rosa, Alberto MLavenberg, Jeffrey AZheng, LuSafren, Steven ANgongondo, McNeilPoongulali, SelvamuthuMatoga, MitchSamaneka, WadzanaiCollier, Ann CHughes, Michael D2018-09-14T18:23:12Z2018-09-14T18:23:12Z2018TORRES, Thiago S. et al. Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. Aids Care, v. 30, n. 8, p. 954 - 962, 2017.0954-0121https://www.arca.fiocruz.br/handle/icict/2880710.1080/09540121.2018.1427207engQuality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settingsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-08-06Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA / Fundação Oswaldo Cruz.Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Center for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USAAsociación Civil Impacta Salud y Educación, Lima, PeruCenter for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USACenter for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USADepartment of Psychology, University of Miami, Miami, FL, USACenter for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USA / UNC Project Lilongwe, Lilongwe, MalawYRGCARE Medical Centre, VHS, Chennai, IndiaUNC Project Lilongwe, Lilongwe, MalawiDepartment of Medicine, University of Zimbabwe-University of California Collaborative Research Programme, Harare, ZimbabweDepartment of Medicine, University of Washington, Seattle, WA, USACenter for Biostatistics in AIDS Research, Harvard T. H. Chan School of Public Health, Boston, MA, USAWe evaluated health-related quality of life (QoL) in HIV infection participants with virologic failure (VF) on first-line antiretroviral therapy (ART) in 9 resource-limited settings (RLS). ACTG SF-21 was completed by 512 participants at A5273 study entry; 8 domains assessed: general health perceptions (GHP), physical functioning (PF), role functioning (RF), social functioning (SF), cognitive functioning (CF), pain (P), mental health (MH), and energy/fatigue (E/F); each was scored between 0 (worst) to 100 (best). Mean QoL scores ranged from 67 (GHP) to 91 (PF, SF, CF). QoL varied by country; high VL and low CD4 were associated with worse QoL in most domains, except RF (VL only), SF (CD4 only) and CF (neither). Number of comorbidities, BMI and history of AIDS were associated with some domains. Relationships between QoL and VL varied among countries for all domains. The association of worse disease status with worse QoL may reflect low QoL when ART was initiated and/or deterioration associated with VF.Health-related quality of lifeHIVVirologic failureAntiretroviral TherapyResource-limited settingsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/28807/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdfQuality of life among HIV infected individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdfapplication/pdf1248317https://www.arca.fiocruz.br/bitstream/icict/28807/2/Quality%20of%20life%20among%20HIV%20infected%20individuals_Thiago_Torres_INI_Lapclin-AIDS_2018.pdf796961560c2e090a094dc540ae28026fMD52TEXTQuality of life among HIV infected 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dc.title.pt_BR.fl_str_mv |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
title |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
spellingShingle |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings Torres, Thiago S Health-related quality of life HIV Virologic failure Antiretroviral Therapy Resource-limited settings |
title_short |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
title_full |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
title_fullStr |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
title_full_unstemmed |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
title_sort |
Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings |
author |
Torres, Thiago S |
author_facet |
Torres, Thiago S Harrison, Linda J La Rosa, Alberto M Lavenberg, Jeffrey A Zheng, Lu Safren, Steven A Ngongondo, McNeil Poongulali, Selvamuthu Matoga, Mitch Samaneka, Wadzanai Collier, Ann C Hughes, Michael D |
author_role |
author |
author2 |
Harrison, Linda J La Rosa, Alberto M Lavenberg, Jeffrey A Zheng, Lu Safren, Steven A Ngongondo, McNeil Poongulali, Selvamuthu Matoga, Mitch Samaneka, Wadzanai Collier, Ann C Hughes, Michael D |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Torres, Thiago S Harrison, Linda J La Rosa, Alberto M Lavenberg, Jeffrey A Zheng, Lu Safren, Steven A Ngongondo, McNeil Poongulali, Selvamuthu Matoga, Mitch Samaneka, Wadzanai Collier, Ann C Hughes, Michael D |
dc.subject.en.pt_BR.fl_str_mv |
Health-related quality of life HIV Virologic failure Antiretroviral Therapy Resource-limited settings |
topic |
Health-related quality of life HIV Virologic failure Antiretroviral Therapy Resource-limited settings |
description |
2020-08-06 |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-09-14T18:23:12Z |
dc.date.available.fl_str_mv |
2018-09-14T18:23:12Z |
dc.date.issued.fl_str_mv |
2018 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
TORRES, Thiago S. et al. Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. Aids Care, v. 30, n. 8, p. 954 - 962, 2017. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/28807 |
dc.identifier.issn.pt_BR.fl_str_mv |
0954-0121 |
dc.identifier.doi.none.fl_str_mv |
10.1080/09540121.2018.1427207 |
identifier_str_mv |
TORRES, Thiago S. et al. Quality of life among HIV-infected individuals failing first-line antiretroviral therapy in resource-limited settings. Aids Care, v. 30, n. 8, p. 954 - 962, 2017. 0954-0121 10.1080/09540121.2018.1427207 |
url |
https://www.arca.fiocruz.br/handle/icict/28807 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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