In good company: association between fungal glycans generates molecular complexes with unique functions
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/27681 |
Resumo: | Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil. |
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Rodrigues, Marcio LourençoNimrichter, Leonardo2018-07-26T18:00:26Z2018-07-26T18:00:26Z2012RODRIGUES, Marcio L.; NIMRICHTER, Leonardo. In good company: association between fungal glycans generates molecular complexes with unique functions. Frontiers in Microbiology, v. 3, p. 1-5, July 2012.1664-302Xhttps://www.arca.fiocruz.br/handle/icict/2768110.3389/fmicb.2012.00249engFrontiers Media S.A.Cryptococcus neoformansDlucuronoxylomannanPolysaccharidesGlycan associationIn good company: association between fungal glycans generates molecular complexes with unique functionsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil.The biological properties of fungal immunogens have historically utilized testing of isolated molecules. Recent findings, however, indicate that fungal glycans differing in structure and function can interact to form hybrid complexes with unique properties. In the pathogenic yeast Cryptococcus neoformans, chitin-like molecules associate with capsular glucuronoxylomannan (GXM) to form functionally distinct glycan complexes. Such interactions between glycans that result in the formation of structures with different functions strongly suggest that additional molecular complexes with unknown properties may exist in fungal pathogens. Moreover, the identification of these novel complexes has stimulated the search of new immunogens with potential to protect human and animal hosts against systemic mycoses.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83101https://www.arca.fiocruz.br/bitstream/icict/27681/1/license.txt425ef259bcb460998407fbfed7c102d0MD51ORIGINALve_Marcio_Rodrigues_CDTS_2012.pdfve_Marcio_Rodrigues_CDTS_2012.pdfapplication/pdf470605https://www.arca.fiocruz.br/bitstream/icict/27681/2/ve_Marcio_Rodrigues_CDTS_2012.pdfc69e8e6959a71bdbc38f21bb8910fa44MD52TEXTve_Marcio_Rodrigues_CDTS_2012.pdf.txtve_Marcio_Rodrigues_CDTS_2012.pdf.txtExtracted texttext/plain30047https://www.arca.fiocruz.br/bitstream/icict/27681/3/ve_Marcio_Rodrigues_CDTS_2012.pdf.txtecde61d1fd550a7220eb9fa017ca7ecfMD53icict/276812023-01-09 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dc.title.pt_BR.fl_str_mv |
In good company: association between fungal glycans generates molecular complexes with unique functions |
title |
In good company: association between fungal glycans generates molecular complexes with unique functions |
spellingShingle |
In good company: association between fungal glycans generates molecular complexes with unique functions Rodrigues, Marcio Lourenço Cryptococcus neoformans Dlucuronoxylomannan Polysaccharides Glycan association |
title_short |
In good company: association between fungal glycans generates molecular complexes with unique functions |
title_full |
In good company: association between fungal glycans generates molecular complexes with unique functions |
title_fullStr |
In good company: association between fungal glycans generates molecular complexes with unique functions |
title_full_unstemmed |
In good company: association between fungal glycans generates molecular complexes with unique functions |
title_sort |
In good company: association between fungal glycans generates molecular complexes with unique functions |
author |
Rodrigues, Marcio Lourenço |
author_facet |
Rodrigues, Marcio Lourenço Nimrichter, Leonardo |
author_role |
author |
author2 |
Nimrichter, Leonardo |
author2_role |
author |
dc.contributor.author.fl_str_mv |
Rodrigues, Marcio Lourenço Nimrichter, Leonardo |
dc.subject.other.pt_BR.fl_str_mv |
Cryptococcus neoformans Dlucuronoxylomannan Polysaccharides Glycan association |
topic |
Cryptococcus neoformans Dlucuronoxylomannan Polysaccharides Glycan association |
description |
Fundação Oswaldo Cruz. Centro de Desenvolvimento Tecnológico em Saúde. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2018-07-26T18:00:26Z |
dc.date.available.fl_str_mv |
2018-07-26T18:00:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
RODRIGUES, Marcio L.; NIMRICHTER, Leonardo. In good company: association between fungal glycans generates molecular complexes with unique functions. Frontiers in Microbiology, v. 3, p. 1-5, July 2012. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/27681 |
dc.identifier.issn.pt_BR.fl_str_mv |
1664-302X |
dc.identifier.doi.none.fl_str_mv |
10.3389/fmicb.2012.00249 |
identifier_str_mv |
RODRIGUES, Marcio L.; NIMRICHTER, Leonardo. In good company: association between fungal glycans generates molecular complexes with unique functions. Frontiers in Microbiology, v. 3, p. 1-5, July 2012. 1664-302X 10.3389/fmicb.2012.00249 |
url |
https://www.arca.fiocruz.br/handle/icict/27681 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
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Frontiers Media S.A. |
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Frontiers Media S.A. |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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