Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/44891 |
Resumo: | Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil. |
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Barreto, Francisca Kalline de AlmeidaAlencar, Carlos HenriqueAraújo, Fernanda Montenegro de CarvalhoOliveira, Rhaquel de Morais Alves BarbosaCavalcante, John WashingtonLemos, Daniele Rocha QueirozFarias, Luís Arthur Brasil GadelhaBoriz, Isac Lucca FrotaMedeiros, Leticia QueirozMelo, Marcelo Nunes PereiraMiyajima, FábioSiqueira, André MachadoFreitas, André Ricardo RibasCavalcanti, Luciano Pamplona de Góes2020-12-15T13:54:46Z2020-12-15T13:54:46Z2020BARRETO, Francisca Kalline de Almeida et al. Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil. BMC Infectious Diseases, v. 20, p. 1-14, 2020.1471-2334https://www.arca.fiocruz.br/handle/icict/4489110.1186/s12879-020-05611-5engBMCSeroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil.Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil / Universidade Federal do Ceará. Programa de Pós-graduação em Patologia. Fortaleza, CE, Brazil.Centro Universitário Christus. Faculdade de Medicina. Fortaleza, CE, Brazil / Laboratório Central de Saúde Pública do Ceará. Fortaleza, CE, Brazil.Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil.Universidade Federal do Ceará. Programa de Pós-graduação em Patologia. Fortaleza, CE, Brazil / Secretaria de Saúde do Estado do Ceará. Serviço de Verificação de Óbitos Dr. Rocha Furtado. Fortaleza, CE, Brazil.Centro Universitário Christus. Faculdade de Medicina. Fortaleza, CE, Brazil.Universidade Federal do Ceará. Faculdade de Medicina. Fortaleza, CE, Brazil / Hospital São José de Doenças infecciosas. Fortaleza, CE, Brazil.Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil.Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil.Centro Universitário Christus. Faculdade de Medicina. Fortaleza, CE, Brazil.Fundação Oswaldo Cruz. Fiocruz Ceará. Eusébio, CE, Brazil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brazil.Faculdade São Leopoldo Mandic. Campinas, SP, Brazil.Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil / Universidade Federal do Ceará. Programa de Pós-graduação em Patologia. Fortaleza, CE, Brazil.Background: The State of Ceará, in Northeastern Brazil, suffers from a triple burden of arboviruses (dengue, Zika and chikungunya). We measured the seroprevalence of chikungunya, dengue and Zika and its associated factors in the population of Juazeiro do Norte, Southern Ceará State, Brazil. Methods: A cross-sectional study of analytical and spatial analysis was performed to estimate the seroprevalence of dengue, Zika and chikungunya, in the year 2018. Participants were tested for IgM and IgG against these three viruses. Those with IgM and/or IgG positive tests results were considered positive. Poisson regression was used to analyze the factors associated with positive cases, in the same way that the spatial analysis of positive cases was performed to verify whether the cases were grouped. Results: Of the 404 participants, 25.0% (103/404) were positive for CHIKV, 92.0% (373/404) for flavivirus (dengue or Zika) and of these, 37.9% (153/404) samples were classified as probable dengue infection. Of those who reported having had an arbovirus in the past, positive CHIKV cases had 58.7% arthralgia (PR = 4.31; 95% CI: 2.06–9.03; p = 0.000) mainly in the hands, ankles and feet. Age over 60 years had a positive association with cases of flavivirus (PR = 1.29; 95% CI: 1.09–1.54; p = 0.000). Fever, muscle pain, joint pain and skin rash were the most reported symptoms (46.1, 41.0, 38.3 and 28.41%, respectively). The positive cases of chikungunya and dengue or Zika were grouped in space and the city center was most affected area. Conclusions: Four years after the introduction of CHIKV, where DENV has been in circulation for over 30 years, 1/4 of the population has already been exposed, showing the extent of the epidemic. The measured prevalence was much higher than that reported by local epidemiological surveillance.SeroprevalenceChikungunya virusDengue virusZika virusinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83099https://www.arca.fiocruz.br/bitstream/icict/44891/1/license.txt586c046dcfeef936e32f0323bb9a47c0MD51ORIGINALSeroprevalence_Andre_Siqueira_etal_INI_2020.pdfSeroprevalence_Andre_Siqueira_etal_INI_2020.pdfapplication/pdf1130099https://www.arca.fiocruz.br/bitstream/icict/44891/2/Seroprevalence_Andre_Siqueira_etal_INI_2020.pdfb8c07e548132aa9406e2b81ece7285acMD52TEXTSeroprevalence_Andre_Siqueira_etal_INI_2020.pdf.txtSeroprevalence_Andre_Siqueira_etal_INI_2020.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| title |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| spellingShingle |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil Barreto, Francisca Kalline de Almeida Seroprevalence Chikungunya virus Dengue virus Zika virus |
| title_short |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| title_full |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| title_fullStr |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| title_full_unstemmed |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| title_sort |
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil |
| author |
Barreto, Francisca Kalline de Almeida |
| author_facet |
Barreto, Francisca Kalline de Almeida Alencar, Carlos Henrique Araújo, Fernanda Montenegro de Carvalho Oliveira, Rhaquel de Morais Alves Barbosa Cavalcante, John Washington Lemos, Daniele Rocha Queiroz Farias, Luís Arthur Brasil Gadelha Boriz, Isac Lucca Frota Medeiros, Leticia Queiroz Melo, Marcelo Nunes Pereira Miyajima, Fábio Siqueira, André Machado Freitas, André Ricardo Ribas Cavalcanti, Luciano Pamplona de Góes |
| author_role |
author |
| author2 |
Alencar, Carlos Henrique Araújo, Fernanda Montenegro de Carvalho Oliveira, Rhaquel de Morais Alves Barbosa Cavalcante, John Washington Lemos, Daniele Rocha Queiroz Farias, Luís Arthur Brasil Gadelha Boriz, Isac Lucca Frota Medeiros, Leticia Queiroz Melo, Marcelo Nunes Pereira Miyajima, Fábio Siqueira, André Machado Freitas, André Ricardo Ribas Cavalcanti, Luciano Pamplona de Góes |
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author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Barreto, Francisca Kalline de Almeida Alencar, Carlos Henrique Araújo, Fernanda Montenegro de Carvalho Oliveira, Rhaquel de Morais Alves Barbosa Cavalcante, John Washington Lemos, Daniele Rocha Queiroz Farias, Luís Arthur Brasil Gadelha Boriz, Isac Lucca Frota Medeiros, Leticia Queiroz Melo, Marcelo Nunes Pereira Miyajima, Fábio Siqueira, André Machado Freitas, André Ricardo Ribas Cavalcanti, Luciano Pamplona de Góes |
| dc.subject.en.pt_BR.fl_str_mv |
Seroprevalence Chikungunya virus Dengue virus Zika virus |
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Seroprevalence Chikungunya virus Dengue virus Zika virus |
| description |
Universidade Federal do Ceará. Programa de Pós-graduação em Saúde Coletiva. Fortaleza, CE, Brazil. |
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2020 |
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2020-12-15T13:54:46Z |
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2020-12-15T13:54:46Z |
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2020 |
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info:eu-repo/semantics/article |
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BARRETO, Francisca Kalline de Almeida et al. Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil. BMC Infectious Diseases, v. 20, p. 1-14, 2020. |
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https://www.arca.fiocruz.br/handle/icict/44891 |
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1471-2334 |
| dc.identifier.doi.pt_BR.fl_str_mv |
10.1186/s12879-020-05611-5 |
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BARRETO, Francisca Kalline de Almeida et al. Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil. BMC Infectious Diseases, v. 20, p. 1-14, 2020. 1471-2334 10.1186/s12879-020-05611-5 |
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