Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine

Detalhes bibliográficos
Autor(a) principal: Conceição, Maria José
Data de Publicação: 2000
Outros Autores: Argento, Carlos Alberto, Corrêa, Acyr
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/44064
Resumo: Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Departamento de Medicina Preventiva. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.
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spelling Conceição, Maria JoséArgento, Carlos AlbertoCorrêa, Acyr2020-10-19T18:19:08Z2020-10-19T18:19:08Z2000CONCEIÇÃO, Maria José; ARGENTO, Carlos Alberto; CORRÊA, Acyr. Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95, n. 3, p. 375-380, May/June 2000.0074-0276https://www.arca.fiocruz.br/handle/icict/4406410.1590/S0074-027620000003000131678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Schistosoma mansoniPacientesOxamniquineFailure of treatmentSchistosoma mansoniPatientsOxamniquineFailure of treatmentStudy of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquineinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Departamento de Medicina Preventiva. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ, Brasil.After three successive treatments with oxamniquine the continuing elimination of Schistosoma mansoni eggs was observed in patients, who came from various regions of Brazil, with different clinical forms of schistosomiasis. The objective of the present study was to determine the experimental behaviour of five different S. mansoni isolates in Swiss Webster mice that were submitted to treatment with the same drug. The experimental group with failure of treatment showed higher mean number of surviving male worms when it was compared to the group without failure of treatment. These date suggest the possibility of resistance to oxamniquine.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/44064/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMariaJConceição_AcyrCorrea_etal_IOC_2000.pdfMariaJConceição_AcyrCorrea_etal_IOC_2000.pdfapplication/pdf56529https://www.arca.fiocruz.br/bitstream/icict/44064/2/MariaJConcei%c3%a7%c3%a3o_AcyrCorrea_etal_IOC_2000.pdfddec52f3e10ddf2fc83b629b5561aedfMD52TEXTMariaJConceição_AcyrCorrea_etal_IOC_2000.pdf.txtMariaJConceição_AcyrCorrea_etal_IOC_2000.pdf.txtExtracted texttext/plain26745https://www.arca.fiocruz.br/bitstream/icict/44064/3/MariaJConcei%c3%a7%c3%a3o_AcyrCorrea_etal_IOC_2000.pdf.txt30a71fc6006cb975568612b47f2c5163MD53icict/440642020-10-20 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dc.title.pt_BR.fl_str_mv Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
title Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
spellingShingle Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
Conceição, Maria José
Schistosoma mansoni
Pacientes
Oxamniquine
Failure of treatment
Schistosoma mansoni
Patients
Oxamniquine
Failure of treatment
title_short Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
title_full Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
title_fullStr Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
title_full_unstemmed Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
title_sort Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine
author Conceição, Maria José
author_facet Conceição, Maria José
Argento, Carlos Alberto
Corrêa, Acyr
author_role author
author2 Argento, Carlos Alberto
Corrêa, Acyr
author2_role author
author
dc.contributor.author.fl_str_mv Conceição, Maria José
Argento, Carlos Alberto
Corrêa, Acyr
dc.subject.other.pt_BR.fl_str_mv Schistosoma mansoni
Pacientes
Oxamniquine
Failure of treatment
topic Schistosoma mansoni
Pacientes
Oxamniquine
Failure of treatment
Schistosoma mansoni
Patients
Oxamniquine
Failure of treatment
dc.subject.en.pt_BR.fl_str_mv Schistosoma mansoni
Patients
Oxamniquine
Failure of treatment
description Universidade Federal do Rio de Janeiro. Hospital Universitário Clementino Fraga Filho. Departamento de Medicina Preventiva. Serviço de Doenças Infecciosas e Parasitárias. Rio de Janeiro, RJ, Brasil.
publishDate 2000
dc.date.issued.fl_str_mv 2000
dc.date.accessioned.fl_str_mv 2020-10-19T18:19:08Z
dc.date.available.fl_str_mv 2020-10-19T18:19:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CONCEIÇÃO, Maria José; ARGENTO, Carlos Alberto; CORRÊA, Acyr. Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95, n. 3, p. 375-380, May/June 2000.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/44064
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02762000000300013
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv CONCEIÇÃO, Maria José; ARGENTO, Carlos Alberto; CORRÊA, Acyr. Study of Schistosoma mansoni Isolates from Patients with Failure of Treatment with Oxamniquine. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 95, n. 3, p. 375-380, May/June 2000.
0074-0276
10.1590/S0074-02762000000300013
1678-8060
url https://www.arca.fiocruz.br/handle/icict/44064
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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instacron_str FIOCRUZ
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