Uso de antimicrobianos nos pacientes em cuidados paliativos admitidos na unidade de terapia intensiva

• Autor(a) principal: Rossetto, Bruno
• Data de Publicação: 2021
• Outros Autores: Souza, Carlos Daniel Handar de, Mio, Enzo May de, Kovalhuk, Maria Eduarda Fleischfresser
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório do Centro Universitário Braz Cubas
• Texto Completo: https://repositorio.cruzeirodosul.edu.br/handle/123456789/3684
• topic: Cuidados paliativos; Antimicrobianos; Unidade de Terapia Intensiva; Tratamento de câncer; CNPQ::CIENCIAS DA SAUDE::MEDICINA

INTRODUCTION: Palliative care (PC) promote the quality of life and suffering relief of patients and their families. In these patients, the use of antimicrobials is still controversial, especially those admitted to the intensive care unit (ICU). OBJECTIVE: To evaluate the use of antimicrobials in PC patients admitted to an ICU of a reference hospital for the treatment of cancer. METHODS: This is a retrospective study during August 2019 to September 2020. Data on demographic profile, hospitalization, PC and use of antimicrobials were collected from the Erasto Gaertner Hospital database. RESULTS: 182 patients were studied, median age of 65 years and 52% men. The main comorbidities were metastatic tumor (50%) and arterial hypertension (44.5%). The median length of stay in the ICU was 3 days; the total length of stay in the hospital was median 6 days and 89.5% died. When comparing patients who used antimicrobials (14.8%) with patients that did not (85.2%), the time in ICU for patients who used antibiotics was significantly longer (120%) (p = 0.033). Regarding the spectrum of antibiotics, the broad-spectrum use did not change the outcome of patients compared with low-spectrum antibiotics. The median length of stay of patients with broad-spectrum antibiotics use was 16 days; 6 days for those with low-spectrum antibiotics (p = 0.033). CONCLUSION: The use of antimicrobials or the type of antibiotics in PC patients admitted to the ICU did not change the mortality rate. Using antibiotics increased the length of stay but did not significantly change the outcome.