Fatal hemothorax caused by pleural mesothelioma in a lion

Detalhes bibliográficos
Autor(a) principal: Rocha,Paulo Ricardo D.
Data de Publicação: 2019
Outros Autores: Duarte,Roberta P., Laranjeira,Maria Gisela, Melo,Tawane Agda L., Azevedo,Eustaquio Z., Garcia,Sergio D., Machado,Gisele F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Pesquisa Veterinária Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2019000600416
Resumo: ABSTRACT: Mesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.
id EMBRAPA-2_f2a132dea6596379ff1339fa6a96fbd9
oai_identifier_str oai:scielo:S0100-736X2019000600416
network_acronym_str EMBRAPA-2
network_name_str Pesquisa Veterinária Brasileira (Online)
repository_id_str
spelling Fatal hemothorax caused by pleural mesothelioma in a lionHemothoraxpleural mesotheliomaimmunohistochemistryPanthera leolionmesotheliomazoo animalwildlife animalspathologyABSTRACT: Mesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.Colégio Brasileiro de Patologia Animal - CBPA2019-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2019000600416Pesquisa Veterinária Brasileira v.39 n.6 2019reponame:Pesquisa Veterinária Brasileira (Online)instname:Colégio Brasileiro de Patologia Animal (CBPA)instacron:EMBRAPA10.1590/1678-5150-pvb-6184info:eu-repo/semantics/openAccessRocha,Paulo Ricardo D.Duarte,Roberta P.Laranjeira,Maria GiselaMelo,Tawane Agda L.Azevedo,Eustaquio Z.Garcia,Sergio D.Machado,Gisele F.eng2019-07-15T00:00:00Zoai:scielo:S0100-736X2019000600416Revistahttp://www.pvb.com.br/https://old.scielo.br/oai/scielo-oai.phpcolegio@cbpa.org.br||pvb@pvb.com.br0100-736X1678-5150opendoar:2019-07-15T00:00Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)false
dc.title.none.fl_str_mv Fatal hemothorax caused by pleural mesothelioma in a lion
title Fatal hemothorax caused by pleural mesothelioma in a lion
spellingShingle Fatal hemothorax caused by pleural mesothelioma in a lion
Rocha,Paulo Ricardo D.
Hemothorax
pleural mesothelioma
immunohistochemistry
Panthera leo
lion
mesothelioma
zoo animal
wildlife animals
pathology
title_short Fatal hemothorax caused by pleural mesothelioma in a lion
title_full Fatal hemothorax caused by pleural mesothelioma in a lion
title_fullStr Fatal hemothorax caused by pleural mesothelioma in a lion
title_full_unstemmed Fatal hemothorax caused by pleural mesothelioma in a lion
title_sort Fatal hemothorax caused by pleural mesothelioma in a lion
author Rocha,Paulo Ricardo D.
author_facet Rocha,Paulo Ricardo D.
Duarte,Roberta P.
Laranjeira,Maria Gisela
Melo,Tawane Agda L.
Azevedo,Eustaquio Z.
Garcia,Sergio D.
Machado,Gisele F.
author_role author
author2 Duarte,Roberta P.
Laranjeira,Maria Gisela
Melo,Tawane Agda L.
Azevedo,Eustaquio Z.
Garcia,Sergio D.
Machado,Gisele F.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rocha,Paulo Ricardo D.
Duarte,Roberta P.
Laranjeira,Maria Gisela
Melo,Tawane Agda L.
Azevedo,Eustaquio Z.
Garcia,Sergio D.
Machado,Gisele F.
dc.subject.por.fl_str_mv Hemothorax
pleural mesothelioma
immunohistochemistry
Panthera leo
lion
mesothelioma
zoo animal
wildlife animals
pathology
topic Hemothorax
pleural mesothelioma
immunohistochemistry
Panthera leo
lion
mesothelioma
zoo animal
wildlife animals
pathology
description ABSTRACT: Mesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.
publishDate 2019
dc.date.none.fl_str_mv 2019-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2019000600416
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2019000600416
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/1678-5150-pvb-6184
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal - CBPA
publisher.none.fl_str_mv Colégio Brasileiro de Patologia Animal - CBPA
dc.source.none.fl_str_mv Pesquisa Veterinária Brasileira v.39 n.6 2019
reponame:Pesquisa Veterinária Brasileira (Online)
instname:Colégio Brasileiro de Patologia Animal (CBPA)
instacron:EMBRAPA
instname_str Colégio Brasileiro de Patologia Animal (CBPA)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Pesquisa Veterinária Brasileira (Online)
collection Pesquisa Veterinária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Veterinária Brasileira (Online) - Colégio Brasileiro de Patologia Animal (CBPA)
repository.mail.fl_str_mv colegio@cbpa.org.br||pvb@pvb.com.br
_version_ 1754122239775604736

Registros relacionados