Fatal hemothorax caused by pleural mesothelioma in a lion

Detalhes bibliográficos
Autor(a) principal: Rocha, Paulo Ricardo D. [UNESP]
Data de Publicação: 2019
Outros Autores: Duarte, Roberta P. [UNESP], Laranjeira, Maria Gisela [UNESP], Melo, Tawane Agda L. [UNESP], Azevedo, Eustaquio Z., Garcia, Sergio D. [UNESP], Machado, Gisele F. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/1678-5150-PVB-6184
http://hdl.handle.net/11449/190508
Resumo: Mesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.
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spelling Fatal hemothorax caused by pleural mesothelioma in a lionHemothoraxImmunohistochemistryLionMesotheliomaPanthera leoPathologyPleural mesotheliomaWildlife animalsZoo animalMesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.Centro de Pesquisas Universidade Paulista (Unip), Avenida José Maria Whitaker 290Faculdade de Medicina Veterinária Universidade Estadual Paulista 'Julio de Mesquita Filho' (Unesp), Rua Clóvis Pestana 793Zoológico Municipal de Araçatuba, Rua do Fico s/nFaculdade de Medicina Veterinária Universidade Estadual Paulista 'Julio de Mesquita Filho' (Unesp), Rua Clóvis Pestana 793Universidade Paulista (Unip)Universidade Estadual Paulista (Unesp)Zoológico Municipal de AraçatubaRocha, Paulo Ricardo D. [UNESP]Duarte, Roberta P. [UNESP]Laranjeira, Maria Gisela [UNESP]Melo, Tawane Agda L. [UNESP]Azevedo, Eustaquio Z.Garcia, Sergio D. [UNESP]Machado, Gisele F. [UNESP]2019-10-06T17:15:30Z2019-10-06T17:15:30Z2019-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article416-418application/pdfhttp://dx.doi.org/10.1590/1678-5150-PVB-6184Pesquisa Veterinaria Brasileira, v. 39, n. 6, p. 416-418, 2019.1678-51500100-736Xhttp://hdl.handle.net/11449/19050810.1590/1678-5150-PVB-6184S0100-736X20190006004162-s2.0-85069453975S0100-736X2019000600416.pdf9599462823853911Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPesquisa Veterinaria Brasileirainfo:eu-repo/semantics/openAccess2024-09-04T18:03:44Zoai:repositorio.unesp.br:11449/190508Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462024-09-04T18:03:44Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Fatal hemothorax caused by pleural mesothelioma in a lion
title Fatal hemothorax caused by pleural mesothelioma in a lion
spellingShingle Fatal hemothorax caused by pleural mesothelioma in a lion
Rocha, Paulo Ricardo D. [UNESP]
Hemothorax
Immunohistochemistry
Lion
Mesothelioma
Panthera leo
Pathology
Pleural mesothelioma
Wildlife animals
Zoo animal
title_short Fatal hemothorax caused by pleural mesothelioma in a lion
title_full Fatal hemothorax caused by pleural mesothelioma in a lion
title_fullStr Fatal hemothorax caused by pleural mesothelioma in a lion
title_full_unstemmed Fatal hemothorax caused by pleural mesothelioma in a lion
title_sort Fatal hemothorax caused by pleural mesothelioma in a lion
author Rocha, Paulo Ricardo D. [UNESP]
author_facet Rocha, Paulo Ricardo D. [UNESP]
Duarte, Roberta P. [UNESP]
Laranjeira, Maria Gisela [UNESP]
Melo, Tawane Agda L. [UNESP]
Azevedo, Eustaquio Z.
Garcia, Sergio D. [UNESP]
Machado, Gisele F. [UNESP]
author_role author
author2 Duarte, Roberta P. [UNESP]
Laranjeira, Maria Gisela [UNESP]
Melo, Tawane Agda L. [UNESP]
Azevedo, Eustaquio Z.
Garcia, Sergio D. [UNESP]
Machado, Gisele F. [UNESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Paulista (Unip)
Universidade Estadual Paulista (Unesp)
Zoológico Municipal de Araçatuba
dc.contributor.author.fl_str_mv Rocha, Paulo Ricardo D. [UNESP]
Duarte, Roberta P. [UNESP]
Laranjeira, Maria Gisela [UNESP]
Melo, Tawane Agda L. [UNESP]
Azevedo, Eustaquio Z.
Garcia, Sergio D. [UNESP]
Machado, Gisele F. [UNESP]
dc.subject.por.fl_str_mv Hemothorax
Immunohistochemistry
Lion
Mesothelioma
Panthera leo
Pathology
Pleural mesothelioma
Wildlife animals
Zoo animal
topic Hemothorax
Immunohistochemistry
Lion
Mesothelioma
Panthera leo
Pathology
Pleural mesothelioma
Wildlife animals
Zoo animal
description Mesothelioma is considered a malignant neoplasm caused by the proliferation of mesothelial cells mostly from the pleura, peritoneum and pericardium. Here we described a case of fatal hemothorax caused by pleural mesothelioma in a lion by means of necropsy, histopathology and immunohistochemistry. Gross inspection of the thoracic cavity showed hemothorax with about 4 liters of blood. Microscopically, numerous, randomly distributed, soft, red-pink, irregular masses with up to 1cm in diameter were observed in both visceral and parietal pleurae. Microscopically, a papillary structure pattern was observed in the thoracic masses, composed mainly by one layer of cubic mesothelial cells, which presented eosinophilic cytoplasm, central nucleus and evident nucleolus, supported by a low cellular fibrovascularstroma. Neoplastic cells were positive for both cytokeratin and vimentin by immunohistochemistry. This seems to be the first report of fatal hemothorax caused by pleural mesothelioma in a lion.
publishDate 2019
dc.date.none.fl_str_mv 2019-10-06T17:15:30Z
2019-10-06T17:15:30Z
2019-01-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1678-5150-PVB-6184
Pesquisa Veterinaria Brasileira, v. 39, n. 6, p. 416-418, 2019.
1678-5150
0100-736X
http://hdl.handle.net/11449/190508
10.1590/1678-5150-PVB-6184
S0100-736X2019000600416
2-s2.0-85069453975
S0100-736X2019000600416.pdf
9599462823853911
url http://dx.doi.org/10.1590/1678-5150-PVB-6184
http://hdl.handle.net/11449/190508
identifier_str_mv Pesquisa Veterinaria Brasileira, v. 39, n. 6, p. 416-418, 2019.
1678-5150
0100-736X
10.1590/1678-5150-PVB-6184
S0100-736X2019000600416
2-s2.0-85069453975
S0100-736X2019000600416.pdf
9599462823853911
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Pesquisa Veterinaria Brasileira
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 416-418
application/pdf
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv repositoriounesp@unesp.br
_version_ 1810021376162004992

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