Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus

Detalhes bibliográficos
Autor(a) principal: Santos, C. C.
Data de Publicação: 2007
Outros Autores: Oliveira, R. R., Figueiredo, M. R.
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Fitos
DOI: 10.32712/2446-4775.2007.80
Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80
Resumo: The Garcinia genus belongs to the Clusiaceae family and contains 200 species distributed in the tropical regions. Ethnopharmacology indicates for this genus the activities: astringent, diuretic and anti-inflammatory and the phytochemical profile shows that the Garcinia genus contains biflavonoids and xanthones as the major constituents. In order to contribute with the chemistry of the species, the methanol extract of leaves was chromatographed in a countercurrent apparatus using the solvent system: n-hexane: ethyl acetate: methanol: water (2:8:5:5) aiming the isolation of metabolites special. The isolated material as yellow crystals was identified as morelloflavona by the 1H and 13C NMR spectrometric analysis.
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spelling Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymusCromatografia Contracorrente no Isolamento de Bisflavonóide de Garcinia xanthochymusCromatografia ContracorrenteGarcinia xanthochymusMorelloflavonaCountercurrent ChromatographyGarcinia xanthochymusMorelloflavoneThe Garcinia genus belongs to the Clusiaceae family and contains 200 species distributed in the tropical regions. Ethnopharmacology indicates for this genus the activities: astringent, diuretic and anti-inflammatory and the phytochemical profile shows that the Garcinia genus contains biflavonoids and xanthones as the major constituents. In order to contribute with the chemistry of the species, the methanol extract of leaves was chromatographed in a countercurrent apparatus using the solvent system: n-hexane: ethyl acetate: methanol: water (2:8:5:5) aiming the isolation of metabolites special. The isolated material as yellow crystals was identified as morelloflavona by the 1H and 13C NMR spectrometric analysis.O gênero Garcinia é pertencente à família Clusiaceae e contém cerca de 200 espécies distribuídas nas regiões tropicais. Dados etnofarmacológicos indicam para algumas espécies desse gênero as atividades: adstringentes, diuréticas e antiinflamatórias e a fitoquímica mostra que o gênero Garcinia contém bisflavonóides e xantonas como seus constituintes majoritários. Em contribuição ao estudo químico da espécie Garcinia xanthochymus, o extrato metanólico das folhas de G. xanthochymus foi cromatografado em aparelho de contracorrente utilizando o sistema de solventes Hexano: Acetato de etila: Metanol: Água (2:8:5:5) visando o isolamento de metabólitos especiais. O material cristalino e de coloração amarela obtido através da elucidação estrutural por técnicas espectrométricas de RMN 1H e 13C foi identificado como morelloflavona. Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz2007-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmlhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/8010.32712/2446-4775.2007.80Revista Fitos; Vol. 3 No. 03 (2007); 32-36Revista Fitos; Vol. 3 Núm. 03 (2007); 32-36Revista Fitos; v. 3 n. 03 (2007); 32-362446-47751808-9569reponame:Revista Fitosinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80/79https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80/1238Copyright (c) 2007 Revista Fitos Eletrônicahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, C. C.Oliveira, R. R.Figueiredo, M. R.2022-10-21T13:10:12Zoai:ojs.revistafitos.far.fiocruz.br:article/80Revistahttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/PUBhttp://revistafitos.far.fiocruz.br/index.php/revista-fitos/oairevistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br2446-47752446-4775opendoar:2022-10-21T13:10:12Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
Cromatografia Contracorrente no Isolamento de Bisflavonóide de Garcinia xanthochymus
title Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
spellingShingle Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
Santos, C. C.
Cromatografia Contracorrente
Garcinia xanthochymus
Morelloflavona
Countercurrent Chromatography
Garcinia xanthochymus
Morelloflavone
Santos, C. C.
Cromatografia Contracorrente
Garcinia xanthochymus
Morelloflavona
Countercurrent Chromatography
Garcinia xanthochymus
Morelloflavone
title_short Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
title_full Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
title_fullStr Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
title_full_unstemmed Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
title_sort Countercurrent Chromatography for the Isolation of Biflavanoids from Garcinia xanthochymus
author Santos, C. C.
author_facet Santos, C. C.
Santos, C. C.
Oliveira, R. R.
Figueiredo, M. R.
Oliveira, R. R.
Figueiredo, M. R.
author_role author
author2 Oliveira, R. R.
Figueiredo, M. R.
author2_role author
author
dc.contributor.author.fl_str_mv Santos, C. C.
Oliveira, R. R.
Figueiredo, M. R.
dc.subject.por.fl_str_mv Cromatografia Contracorrente
Garcinia xanthochymus
Morelloflavona
Countercurrent Chromatography
Garcinia xanthochymus
Morelloflavone
topic Cromatografia Contracorrente
Garcinia xanthochymus
Morelloflavona
Countercurrent Chromatography
Garcinia xanthochymus
Morelloflavone
description The Garcinia genus belongs to the Clusiaceae family and contains 200 species distributed in the tropical regions. Ethnopharmacology indicates for this genus the activities: astringent, diuretic and anti-inflammatory and the phytochemical profile shows that the Garcinia genus contains biflavonoids and xanthones as the major constituents. In order to contribute with the chemistry of the species, the methanol extract of leaves was chromatographed in a countercurrent apparatus using the solvent system: n-hexane: ethyl acetate: methanol: water (2:8:5:5) aiming the isolation of metabolites special. The isolated material as yellow crystals was identified as morelloflavona by the 1H and 13C NMR spectrometric analysis.
publishDate 2007
dc.date.none.fl_str_mv 2007-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80
10.32712/2446-4775.2007.80
url https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80
identifier_str_mv 10.32712/2446-4775.2007.80
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80/79
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/80/1238
dc.rights.driver.fl_str_mv Copyright (c) 2007 Revista Fitos Eletrônica
https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2007 Revista Fitos Eletrônica
https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz
publisher.none.fl_str_mv Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz
dc.source.none.fl_str_mv Revista Fitos; Vol. 3 No. 03 (2007); 32-36
Revista Fitos; Vol. 3 Núm. 03 (2007); 32-36
Revista Fitos; v. 3 n. 03 (2007); 32-36
2446-4775
1808-9569
reponame:Revista Fitos
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Revista Fitos
collection Revista Fitos
repository.name.fl_str_mv Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv revistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br
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dc.identifier.doi.none.fl_str_mv 10.32712/2446-4775.2007.80

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