Antibacterial and topical anti-inflammatory effect of methanol extract of Chenopodium ambrosioides L.

• Autor(a) principal: Pereira, Nara Luana Ferreira
• Data de Publicação: 2015
• Outros Autores: Aquino, Pedro Everson Alexandre de, Nascimento, Eloiza Maria do, Morais Oliveira, Cícera Datiane de, Tintino, Saulo Relison, Figueredo, Fernando Gomes, Silva, Monalisa Ribeiro, Veras, Helenicy Nogueira Holanda, Grangeiro, Ana Ruth Sampaio, Menezes, Irwin Rose Alencar de
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Fitos
• Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/236
• topic: Chenopodium ambrosioides L.; Minimum Inhibitory Concentration; Phenols; Flavonoids; Inflammation; Modulation; Chenopodium ambrosioides L.; Concetração Inibitória Mínima; Fenóis; Flavonoides; Inflamação; Modulação

The use of medicinal plants is a common practice in countries as part of popular culture as a treatment of different pathologies. The Chenopodium ambrosioides L. plant, popularly known as Mastruz, is used in folk medicine to treat chronic bronchitis, tuberculosis, bruises, fractures and hernias, and some activities scientifically proven as anthelmintic and antimicrobial action. Thus, this study aimed to evaluate the chemical profile and investigate the antibacterial activity, modulator of antibiotics and topical anti-inflammatory of methanol extract obtained from Chenopodium ambrosioides L. leaves. In the phytochemical extract prospecting, they were checked different metabolites that have multiple biological activity, and the dosage of total phenols were checked 21.0 mg / g gallic acid equivalent, and the quantification of flavonoids found a total of 135.4 mg / g quercetin. There was no antibacterial activity, but modulation was detected when the extract was associated with aminoglycosides against strains of E. coli and Staphylococcus aureus. In tests for acute inflammation, the extract showed an antiedematogenic potential at concentrations of 25 and 50 mg. Given the results, we can correlate the empirical knowledge of people; the biological properties observed in this study, this may be important for future validation of these ethnomedicinal properties.