The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata

Detalhes bibliográficos
Autor(a) principal: Serrano,Deborah Regina
Data de Publicação: 2002
Outros Autores: Zanotti-Magalhães,Eliana Maria, Magalhães,Luiz Augusto, Carvalho,José Ferreira de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024
Resumo: Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.
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spelling The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrataSchistosoma mansoniBiomphalaria glabratahydrocortisonesporocysthemocyte reactionSince the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.Instituto Oswaldo Cruz, Ministério da Saúde2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024Memórias do Instituto Oswaldo Cruz v.97 n.6 2002reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762002000600024info:eu-repo/semantics/openAccessSerrano,Deborah ReginaZanotti-Magalhães,Eliana MariaMagalhães,Luiz AugustoCarvalho,José Ferreira deeng2020-04-25T17:48:51Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:11:21.889Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
title The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
spellingShingle The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
Serrano,Deborah Regina
Schistosoma mansoni
Biomphalaria glabrata
hydrocortisone
sporocyst
hemocyte reaction
title_short The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
title_full The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
title_fullStr The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
title_full_unstemmed The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
title_sort The influence of hydrocortisone on cellular defence mechanisms of Biomphalaria glabrata
author Serrano,Deborah Regina
author_facet Serrano,Deborah Regina
Zanotti-Magalhães,Eliana Maria
Magalhães,Luiz Augusto
Carvalho,José Ferreira de
author_role author
author2 Zanotti-Magalhães,Eliana Maria
Magalhães,Luiz Augusto
Carvalho,José Ferreira de
author2_role author
author
author
dc.contributor.author.fl_str_mv Serrano,Deborah Regina
Zanotti-Magalhães,Eliana Maria
Magalhães,Luiz Augusto
Carvalho,José Ferreira de
dc.subject.por.fl_str_mv Schistosoma mansoni
Biomphalaria glabrata
hydrocortisone
sporocyst
hemocyte reaction
topic Schistosoma mansoni
Biomphalaria glabrata
hydrocortisone
sporocyst
hemocyte reaction
dc.description.none.fl_txt_mv Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.
description Since the internal defense system of mollusks consists of cellular and humoral mechanisms, we examined the role of hydrocortisone in mollusks defense cells and the influence of this steroid on the development of Schistosoma mansoni in its intermediary host. Hydrocortisone had an immunosuppressive action in Biomphalaria glabrata, as reflected in the reduced number of defense cells and the altered cell physiology. Histopathological analysis showed that hydrocortisone facilitated the intramolluscan development of S. mansoni, by reducing the extent of the inflammatory response, seen as a greater number of viable sporocysts with no surrounding hemocytes.
publishDate 2002
dc.date.none.fl_str_mv 2002-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762002000600024
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762002000600024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.97 n.6 2002
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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