Lipoxin agonists: turn right! to path of resolving neutrophil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2005 |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Memórias do Instituto Oswaldo Cruz |
| Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010 |
Resumo: | An impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original centered state. This article focuses on some aspects of the lipoxin A4 signaling pathway during the resolution phase, to better understand molecular mechanisms by which a neutrophil directs an inflammatory reaction to switch off and resume homeostasis. Defining the resolution state of a neutrophil at the molecular level will aid in treatments of diseases that are associated with an exaggerated and uncontrolled inflammation. |
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Lipoxin agonists: turn right! to path of resolving neutrophilneutrophillipid mediatorsresolution of inflammationAn impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original centered state. This article focuses on some aspects of the lipoxin A4 signaling pathway during the resolution phase, to better understand molecular mechanisms by which a neutrophil directs an inflammatory reaction to switch off and resume homeostasis. Defining the resolution state of a neutrophil at the molecular level will aid in treatments of diseases that are associated with an exaggerated and uncontrolled inflammation.Instituto Oswaldo Cruz, Ministério da Saúde2005-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010Memórias do Instituto Oswaldo Cruz v.100 suppl.1 2005reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762005000900010info:eu-repo/semantics/openAccessDevchand,Pallavi Reng2020-04-25T17:49:30Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:13:30.198Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
| dc.title.none.fl_str_mv |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| title |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| spellingShingle |
Lipoxin agonists: turn right! to path of resolving neutrophil Devchand,Pallavi R neutrophil lipid mediators resolution of inflammation |
| title_short |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_full |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_fullStr |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_full_unstemmed |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| title_sort |
Lipoxin agonists: turn right! to path of resolving neutrophil |
| author |
Devchand,Pallavi R |
| author_facet |
Devchand,Pallavi R |
| author_role |
author |
| dc.contributor.author.fl_str_mv |
Devchand,Pallavi R |
| dc.subject.por.fl_str_mv |
neutrophil lipid mediators resolution of inflammation |
| topic |
neutrophil lipid mediators resolution of inflammation |
| dc.description.none.fl_txt_mv |
An impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original centered state. This article focuses on some aspects of the lipoxin A4 signaling pathway during the resolution phase, to better understand molecular mechanisms by which a neutrophil directs an inflammatory reaction to switch off and resume homeostasis. Defining the resolution state of a neutrophil at the molecular level will aid in treatments of diseases that are associated with an exaggerated and uncontrolled inflammation. |
| description |
An impressive array of cellular and molecular adaptive responses achieves homeostasis. The inflammatory reaction is an adaptive response triggered by an insult to culminate into the overt cardinal signs of inflammation, eventually leading to resolution and returning the organism back to its original centered state. This article focuses on some aspects of the lipoxin A4 signaling pathway during the resolution phase, to better understand molecular mechanisms by which a neutrophil directs an inflammatory reaction to switch off and resume homeostasis. Defining the resolution state of a neutrophil at the molecular level will aid in treatments of diseases that are associated with an exaggerated and uncontrolled inflammation. |
| publishDate |
2005 |
| dc.date.none.fl_str_mv |
2005-03-01 |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010 |
| url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000900010 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
10.1590/S0074-02762005000900010 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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text/html |
| dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
| dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.100 suppl.1 2005 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz |
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Memórias do Instituto Oswaldo Cruz |
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Fundação Oswaldo Cruz |
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FIOCRUZ |
| institution |
FIOCRUZ |
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Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
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1669937694412636160 |