Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)

Detalhes bibliográficos
Autor(a) principal: Pirmez,Claude
Data de Publicação: 1988
Outros Autores: Marzochi,Mauro C. A., Coutinho,Sergio G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761988000200001
Resumo: Four mongrel dogs were intradermically inoculated with 3 x 10**6 Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. Clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. These results suggest that dogs may be an useful model for L. b. braziliensis infection.
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spelling Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)Leishmania braziliensis braziliensiscanine experimental infectionFour mongrel dogs were intradermically inoculated with 3 x 10**6 Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. Clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. These results suggest that dogs may be an useful model for L. b. braziliensis infection.Instituto Oswaldo Cruz, Ministério da Saúde1988-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761988000200001Memórias do Instituto Oswaldo Cruz v.83 n.2 1988reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761988000200001info:eu-repo/semantics/openAccessPirmez,ClaudeMarzochi,Mauro C. A.Coutinho,Sergio G.eng2020-04-25T17:46:06Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:02:22.267Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
title Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
spellingShingle Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
Pirmez,Claude
Leishmania braziliensis braziliensis
canine experimental infection
title_short Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
title_full Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
title_fullStr Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
title_full_unstemmed Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
title_sort Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis)
author Pirmez,Claude
author_facet Pirmez,Claude
Marzochi,Mauro C. A.
Coutinho,Sergio G.
author_role author
author2 Marzochi,Mauro C. A.
Coutinho,Sergio G.
author2_role author
author
dc.contributor.author.fl_str_mv Pirmez,Claude
Marzochi,Mauro C. A.
Coutinho,Sergio G.
dc.subject.por.fl_str_mv Leishmania braziliensis braziliensis
canine experimental infection
topic Leishmania braziliensis braziliensis
canine experimental infection
dc.description.none.fl_txt_mv Four mongrel dogs were intradermically inoculated with 3 x 10**6 Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. Clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. These results suggest that dogs may be an useful model for L. b. braziliensis infection.
description Four mongrel dogs were intradermically inoculated with 3 x 10**6 Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. Clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. These results suggest that dogs may be an useful model for L. b. braziliensis infection.
publishDate 1988
dc.date.none.fl_str_mv 1988-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761988000200001
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761988000200001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761988000200001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.83 n.2 1988
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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