The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene

Detalhes bibliográficos
Autor(a) principal: Sampaio,MCR
Data de Publicação: 2003
Outros Autores: Traub-Cseko,YM
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300014
Resumo: Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described.
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spelling The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter geneLeishmania (V.) braziliensissmall chromosomegenomic amplificationLeishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described.Instituto Oswaldo Cruz, Ministério da Saúde2003-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300014Memórias do Instituto Oswaldo Cruz v.98 n.3 2003reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762003000300014info:eu-repo/semantics/openAccessSampaio,MCRTraub-Cseko,YMeng2020-04-25T17:49:03Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:11:54.224Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
title The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
spellingShingle The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
Sampaio,MCR
Leishmania (V.) braziliensis
small chromosome
genomic amplification
title_short The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
title_full The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
title_fullStr The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
title_full_unstemmed The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
title_sort The 245 kb amplified chromosome of Leishmania (V.) braziliensis contains a biopterin transporter gene
author Sampaio,MCR
author_facet Sampaio,MCR
Traub-Cseko,YM
author_role author
author2 Traub-Cseko,YM
author2_role author
dc.contributor.author.fl_str_mv Sampaio,MCR
Traub-Cseko,YM
dc.subject.por.fl_str_mv Leishmania (V.) braziliensis
small chromosome
genomic amplification
topic Leishmania (V.) braziliensis
small chromosome
genomic amplification
dc.description.none.fl_txt_mv Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described.
description Leishmania (V.) braziliensis M2903 presents a small linear and stable 245 kb chromosome originating from a genomic amplification. Similar amplifications present in other species of Leishmania contain a gene coding for a biopterin transporter. Since Leishmania is auxotrophic for this metabolite, this amplification could result from the need to better capture biotpterin from growth media under specific circumstances. In this paper we show that this gene is also present in L. (V.) braziliensis small chromosome, which shares sequences with other genomic amplifications already described.
publishDate 2003
dc.date.none.fl_str_mv 2003-04-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300014
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000300014
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762003000300014
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.98 n.3 2003
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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