Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Memórias do Instituto Oswaldo Cruz |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000400017 |
Resumo: | The parotid lymph nodes of naive and previously infected Balb/c mice were studied after, respectively, infection and re-infection with cercariae of Schistosoma mansoni via the ears. Schistosomula were able to pass through the lymph node by following the lymph flow or by penetrating the veins of the medullary cords. The number of nodal mast cells was higher from day 2 to 6 of primary infection; and from day 5 to 11 of re-infection. The amount of degranulating mast cells was significantly higher at day 4 of infection and at day 1 of re-infection. Eosinophils characterized the nodal inflammatory processes observed after day 5 in both primarily-infected and re-infected mice. However, only in the latter the eosinophils were able to adhere to the larval surface. In primarily-infected mice, no intranodal larva presented signs of degeneration. In contrast, in re-infected animals, some degenerating larvae were found inside eosinophilic infiltrates. The eosinophils reached the nodal tissue by migrating through the high endothelial venules and their collecting veins. |
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Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected miceSchistosoma mansonilymph nodesschistosomulum migrationeosinophilsmast cellshigh endothelial venulesThe parotid lymph nodes of naive and previously infected Balb/c mice were studied after, respectively, infection and re-infection with cercariae of Schistosoma mansoni via the ears. Schistosomula were able to pass through the lymph node by following the lymph flow or by penetrating the veins of the medullary cords. The number of nodal mast cells was higher from day 2 to 6 of primary infection; and from day 5 to 11 of re-infection. The amount of degranulating mast cells was significantly higher at day 4 of infection and at day 1 of re-infection. Eosinophils characterized the nodal inflammatory processes observed after day 5 in both primarily-infected and re-infected mice. However, only in the latter the eosinophils were able to adhere to the larval surface. In primarily-infected mice, no intranodal larva presented signs of degeneration. In contrast, in re-infected animals, some degenerating larvae were found inside eosinophilic infiltrates. The eosinophils reached the nodal tissue by migrating through the high endothelial venules and their collecting veins.Instituto Oswaldo Cruz, Ministério da Saúde1996-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000400017Memórias do Instituto Oswaldo Cruz v.91 n.4 1996reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761996000400017info:eu-repo/semantics/openAccessLozzi,Silene PMachado,Conceição RSGerken,Silvia EMota-Santos,Tomas Aeng2020-04-25T17:47:35Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:07:06.435Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue |
dc.title.none.fl_str_mv |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
title |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
spellingShingle |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice Lozzi,Silene P Schistosoma mansoni lymph nodes schistosomulum migration eosinophils mast cells high endothelial venules |
title_short |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
title_full |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
title_fullStr |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
title_full_unstemmed |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
title_sort |
Involvement of regional lymph nodes after penetration of Schistosoma mansoni cercariae in naive and infected mice |
author |
Lozzi,Silene P |
author_facet |
Lozzi,Silene P Machado,Conceição RS Gerken,Silvia E Mota-Santos,Tomas A |
author_role |
author |
author2 |
Machado,Conceição RS Gerken,Silvia E Mota-Santos,Tomas A |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Lozzi,Silene P Machado,Conceição RS Gerken,Silvia E Mota-Santos,Tomas A |
dc.subject.por.fl_str_mv |
Schistosoma mansoni lymph nodes schistosomulum migration eosinophils mast cells high endothelial venules |
topic |
Schistosoma mansoni lymph nodes schistosomulum migration eosinophils mast cells high endothelial venules |
dc.description.none.fl_txt_mv |
The parotid lymph nodes of naive and previously infected Balb/c mice were studied after, respectively, infection and re-infection with cercariae of Schistosoma mansoni via the ears. Schistosomula were able to pass through the lymph node by following the lymph flow or by penetrating the veins of the medullary cords. The number of nodal mast cells was higher from day 2 to 6 of primary infection; and from day 5 to 11 of re-infection. The amount of degranulating mast cells was significantly higher at day 4 of infection and at day 1 of re-infection. Eosinophils characterized the nodal inflammatory processes observed after day 5 in both primarily-infected and re-infected mice. However, only in the latter the eosinophils were able to adhere to the larval surface. In primarily-infected mice, no intranodal larva presented signs of degeneration. In contrast, in re-infected animals, some degenerating larvae were found inside eosinophilic infiltrates. The eosinophils reached the nodal tissue by migrating through the high endothelial venules and their collecting veins. |
description |
The parotid lymph nodes of naive and previously infected Balb/c mice were studied after, respectively, infection and re-infection with cercariae of Schistosoma mansoni via the ears. Schistosomula were able to pass through the lymph node by following the lymph flow or by penetrating the veins of the medullary cords. The number of nodal mast cells was higher from day 2 to 6 of primary infection; and from day 5 to 11 of re-infection. The amount of degranulating mast cells was significantly higher at day 4 of infection and at day 1 of re-infection. Eosinophils characterized the nodal inflammatory processes observed after day 5 in both primarily-infected and re-infected mice. However, only in the latter the eosinophils were able to adhere to the larval surface. In primarily-infected mice, no intranodal larva presented signs of degeneration. In contrast, in re-infected animals, some degenerating larvae were found inside eosinophilic infiltrates. The eosinophils reached the nodal tissue by migrating through the high endothelial venules and their collecting veins. |
publishDate |
1996 |
dc.date.none.fl_str_mv |
1996-08-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000400017 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000400017 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0074-02761996000400017 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
publisher.none.fl_str_mv |
Instituto Oswaldo Cruz, Ministério da Saúde |
dc.source.none.fl_str_mv |
Memórias do Instituto Oswaldo Cruz v.91 n.4 1996 reponame:Memórias do Instituto Oswaldo Cruz instname:Fundação Oswaldo Cruz instacron:FIOCRUZ |
reponame_str |
Memórias do Instituto Oswaldo Cruz |
collection |
Memórias do Instituto Oswaldo Cruz |
instname_str |
Fundação Oswaldo Cruz |
instacron_str |
FIOCRUZ |
institution |
FIOCRUZ |
repository.name.fl_str_mv |
Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz |
repository.mail.fl_str_mv |
|
_version_ |
1669937667277586432 |