Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus

Detalhes bibliográficos
Autor(a) principal: De Carli,Geraldo A
Data de Publicação: 1996
Outros Autores: Brasseur,Philippe, Silva,Ana C da, Wendorff,Aline, Rott,Marilise
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000100019
Resumo: The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.
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spelling Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetusTrichomonas vaginalisTritrichomonas foetushemolytic activityisolatesclonesThe hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.Instituto Oswaldo Cruz, Ministério da Saúde1996-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000100019Memórias do Instituto Oswaldo Cruz v.91 n.1 1996reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761996000100019info:eu-repo/semantics/openAccessDe Carli,Geraldo ABrasseur,PhilippeSilva,Ana C daWendorff,AlineRott,Mariliseeng2020-04-25T17:47:30Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:06:51.889Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
title Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
spellingShingle Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
De Carli,Geraldo A
Trichomonas vaginalis
Tritrichomonas foetus
hemolytic activity
isolates
clones
title_short Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
title_full Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
title_fullStr Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
title_full_unstemmed Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
title_sort Hemolytic activity of Trichomonas vaginalis and Tritrichomonas foetus
author De Carli,Geraldo A
author_facet De Carli,Geraldo A
Brasseur,Philippe
Silva,Ana C da
Wendorff,Aline
Rott,Marilise
author_role author
author2 Brasseur,Philippe
Silva,Ana C da
Wendorff,Aline
Rott,Marilise
author2_role author
author
author
author
dc.contributor.author.fl_str_mv De Carli,Geraldo A
Brasseur,Philippe
Silva,Ana C da
Wendorff,Aline
Rott,Marilise
dc.subject.por.fl_str_mv Trichomonas vaginalis
Tritrichomonas foetus
hemolytic activity
isolates
clones
topic Trichomonas vaginalis
Tritrichomonas foetus
hemolytic activity
isolates
clones
dc.description.none.fl_txt_mv The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.
description The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.
publishDate 1996
dc.date.none.fl_str_mv 1996-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000100019
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761996000100019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761996000100019
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.91 n.1 1996
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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