Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus

Detalhes bibliográficos
Autor(a) principal: De Carli, Geraldo Attilio
Data de Publicação: 1996
Outros Autores: Brasseur, Philippe, Silva, Ana Maria C. da, Wendorff, Aline T., Rott, Marilise Brittes
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/19244
Resumo: The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.
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spelling De Carli, Geraldo AttilioBrasseur, PhilippeSilva, Ana Maria C. daWendorff, Aline T.Rott, Marilise Brittes2010-04-16T09:08:55Z19960074-0276http://hdl.handle.net/10183/19244000112614The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.application/pdfengMemórias do Instituto Oswaldo Cruz : an international journal of biological and biomedical research. Rio de Janeiro, RJ. Vol. 9, n. 1 (jan./fev. 1996), p. 107-110Trichomonas vaginalisTritrichomonas foetusTrichomonas vaginalisTritrichomonas foetusHemolytic activityIsolatesClonesHemolitic activity of trichomonas vaginalis and tritrichomonas foetusinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000112614.pdf000112614.pdfTexto completo (inglês)application/pdf65563http://www.lume.ufrgs.br/bitstream/10183/19244/1/000112614.pdf7b0ea2dd6a5bf9dd86dec6259327758dMD51TEXT000112614.pdf.txt000112614.pdf.txtExtracted Texttext/plain17728http://www.lume.ufrgs.br/bitstream/10183/19244/2/000112614.pdf.txt1692f639a4f820481f10a125e3ac91d0MD52THUMBNAIL000112614.pdf.jpg000112614.pdf.jpgGenerated Thumbnailimage/jpeg1994http://www.lume.ufrgs.br/bitstream/10183/19244/3/000112614.pdf.jpgba603de1a8cc7e5061a13b403c2a4aebMD5310183/192442018-10-08 08:05:51.408oai:www.lume.ufrgs.br:10183/19244Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-08T11:05:51Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
title Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
spellingShingle Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
De Carli, Geraldo Attilio
Trichomonas vaginalis
Tritrichomonas foetus
Trichomonas vaginalis
Tritrichomonas foetus
Hemolytic activity
Isolates
Clones
title_short Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
title_full Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
title_fullStr Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
title_full_unstemmed Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
title_sort Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
author De Carli, Geraldo Attilio
author_facet De Carli, Geraldo Attilio
Brasseur, Philippe
Silva, Ana Maria C. da
Wendorff, Aline T.
Rott, Marilise Brittes
author_role author
author2 Brasseur, Philippe
Silva, Ana Maria C. da
Wendorff, Aline T.
Rott, Marilise Brittes
author2_role author
author
author
author
dc.contributor.author.fl_str_mv De Carli, Geraldo Attilio
Brasseur, Philippe
Silva, Ana Maria C. da
Wendorff, Aline T.
Rott, Marilise Brittes
dc.subject.por.fl_str_mv Trichomonas vaginalis
Tritrichomonas foetus
topic Trichomonas vaginalis
Tritrichomonas foetus
Trichomonas vaginalis
Tritrichomonas foetus
Hemolytic activity
Isolates
Clones
dc.subject.eng.fl_str_mv Trichomonas vaginalis
Tritrichomonas foetus
Hemolytic activity
Isolates
Clones
description The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.
publishDate 1996
dc.date.issued.fl_str_mv 1996
dc.date.accessioned.fl_str_mv 2010-04-16T09:08:55Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/19244
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.nrb.pt_BR.fl_str_mv 000112614
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url http://hdl.handle.net/10183/19244
dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv Memórias do Instituto Oswaldo Cruz : an international journal of biological and biomedical research. Rio de Janeiro, RJ. Vol. 9, n. 1 (jan./fev. 1996), p. 107-110
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