Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus
Autor(a) principal: | |
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Data de Publicação: | 1996 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/19244 |
Resumo: | The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%. |
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De Carli, Geraldo AttilioBrasseur, PhilippeSilva, Ana Maria C. daWendorff, Aline T.Rott, Marilise Brittes2010-04-16T09:08:55Z19960074-0276http://hdl.handle.net/10183/19244000112614The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%.application/pdfengMemórias do Instituto Oswaldo Cruz : an international journal of biological and biomedical research. Rio de Janeiro, RJ. Vol. 9, n. 1 (jan./fev. 1996), p. 107-110Trichomonas vaginalisTritrichomonas foetusTrichomonas vaginalisTritrichomonas foetusHemolytic activityIsolatesClonesHemolitic activity of trichomonas vaginalis and tritrichomonas foetusinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000112614.pdf000112614.pdfTexto completo (inglês)application/pdf65563http://www.lume.ufrgs.br/bitstream/10183/19244/1/000112614.pdf7b0ea2dd6a5bf9dd86dec6259327758dMD51TEXT000112614.pdf.txt000112614.pdf.txtExtracted Texttext/plain17728http://www.lume.ufrgs.br/bitstream/10183/19244/2/000112614.pdf.txt1692f639a4f820481f10a125e3ac91d0MD52THUMBNAIL000112614.pdf.jpg000112614.pdf.jpgGenerated Thumbnailimage/jpeg1994http://www.lume.ufrgs.br/bitstream/10183/19244/3/000112614.pdf.jpgba603de1a8cc7e5061a13b403c2a4aebMD5310183/192442018-10-08 08:05:51.408oai:www.lume.ufrgs.br:10183/19244Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-08T11:05:51Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
title |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
spellingShingle |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus De Carli, Geraldo Attilio Trichomonas vaginalis Tritrichomonas foetus Trichomonas vaginalis Tritrichomonas foetus Hemolytic activity Isolates Clones |
title_short |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
title_full |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
title_fullStr |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
title_full_unstemmed |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
title_sort |
Hemolitic activity of trichomonas vaginalis and tritrichomonas foetus |
author |
De Carli, Geraldo Attilio |
author_facet |
De Carli, Geraldo Attilio Brasseur, Philippe Silva, Ana Maria C. da Wendorff, Aline T. Rott, Marilise Brittes |
author_role |
author |
author2 |
Brasseur, Philippe Silva, Ana Maria C. da Wendorff, Aline T. Rott, Marilise Brittes |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
De Carli, Geraldo Attilio Brasseur, Philippe Silva, Ana Maria C. da Wendorff, Aline T. Rott, Marilise Brittes |
dc.subject.por.fl_str_mv |
Trichomonas vaginalis Tritrichomonas foetus |
topic |
Trichomonas vaginalis Tritrichomonas foetus Trichomonas vaginalis Tritrichomonas foetus Hemolytic activity Isolates Clones |
dc.subject.eng.fl_str_mv |
Trichomonas vaginalis Tritrichomonas foetus Hemolytic activity Isolates Clones |
description |
The hemolytic activity of live isolates and clones of Trichomonas vaginalis and Tritrichomonas foetus was investigated. The isolates were tested against human erythrocytes. No hemolytic activity was detected by the isolates of T. foetus. Whereas the isolates of T. vaginalis lysed erythrocytes from all human blood groups. No hemolysin released by the parasites could be detected. Our preliminary results suggest that hemolysis depend on the susceptibility of red cell membranes to destabilization and the intervention of cell surface receptors as a mechanism of the hemolytic activity. The mechanism could be subject to strain-species-genera specific variation of trichomonads. The hemolytic activity of T. vaginalis is not due to a hemolysin or to a product of its metabolism. Pretreatment of trichomonads with concanavalin A reduced levels of hemolysis by 40%. |
publishDate |
1996 |
dc.date.issued.fl_str_mv |
1996 |
dc.date.accessioned.fl_str_mv |
2010-04-16T09:08:55Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/other |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/19244 |
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0074-0276 |
dc.identifier.nrb.pt_BR.fl_str_mv |
000112614 |
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0074-0276 000112614 |
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http://hdl.handle.net/10183/19244 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Memórias do Instituto Oswaldo Cruz : an international journal of biological and biomedical research. Rio de Janeiro, RJ. Vol. 9, n. 1 (jan./fev. 1996), p. 107-110 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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