Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice

Detalhes bibliográficos
Autor(a) principal: Santos,Rosella de Oliveira
Data de Publicação: 1992
Outros Autores: Barbosa Júnior,Aryon A., Andrade,Zilton A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100005
Resumo: A histological, morphometric and immunocytochemical study of schistosomal periovular granulomas in the liver and intestines of mice revealed that intestinal granulomas are smaller and contain less collagen than those in the liver. After curative treatment intestinal granulomas undergo a relatively more rapid resorption, although the general pattern of collagen degradation apparently does not differ from that observed in the liver. Tendency to form scattered, usually isolated granulomas that are only mildly fibrogenic, coupled with a well-balanced process of resorption appear as the explanation why intestinal fibrosis is not an outstanding feature of schistosomiasis as it is in the liver.
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spelling Dynamics of fibrosis production and resorption in intestinal schistosomiasis of miceschistosomiasisintestinal fibrosisperiovular granulomaA histological, morphometric and immunocytochemical study of schistosomal periovular granulomas in the liver and intestines of mice revealed that intestinal granulomas are smaller and contain less collagen than those in the liver. After curative treatment intestinal granulomas undergo a relatively more rapid resorption, although the general pattern of collagen degradation apparently does not differ from that observed in the liver. Tendency to form scattered, usually isolated granulomas that are only mildly fibrogenic, coupled with a well-balanced process of resorption appear as the explanation why intestinal fibrosis is not an outstanding feature of schistosomiasis as it is in the liver.Instituto Oswaldo Cruz, Ministério da Saúde1992-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100005Memórias do Instituto Oswaldo Cruz v.87 n.1 1992reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761992000100005info:eu-repo/semantics/openAccessSantos,Rosella de OliveiraBarbosa Júnior,Aryon A.Andrade,Zilton A.eng2020-04-25T17:46:42Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:04:28.965Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
title Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
spellingShingle Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
Santos,Rosella de Oliveira
schistosomiasis
intestinal fibrosis
periovular granuloma
title_short Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
title_full Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
title_fullStr Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
title_full_unstemmed Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
title_sort Dynamics of fibrosis production and resorption in intestinal schistosomiasis of mice
author Santos,Rosella de Oliveira
author_facet Santos,Rosella de Oliveira
Barbosa Júnior,Aryon A.
Andrade,Zilton A.
author_role author
author2 Barbosa Júnior,Aryon A.
Andrade,Zilton A.
author2_role author
author
dc.contributor.author.fl_str_mv Santos,Rosella de Oliveira
Barbosa Júnior,Aryon A.
Andrade,Zilton A.
dc.subject.por.fl_str_mv schistosomiasis
intestinal fibrosis
periovular granuloma
topic schistosomiasis
intestinal fibrosis
periovular granuloma
dc.description.none.fl_txt_mv A histological, morphometric and immunocytochemical study of schistosomal periovular granulomas in the liver and intestines of mice revealed that intestinal granulomas are smaller and contain less collagen than those in the liver. After curative treatment intestinal granulomas undergo a relatively more rapid resorption, although the general pattern of collagen degradation apparently does not differ from that observed in the liver. Tendency to form scattered, usually isolated granulomas that are only mildly fibrogenic, coupled with a well-balanced process of resorption appear as the explanation why intestinal fibrosis is not an outstanding feature of schistosomiasis as it is in the liver.
description A histological, morphometric and immunocytochemical study of schistosomal periovular granulomas in the liver and intestines of mice revealed that intestinal granulomas are smaller and contain less collagen than those in the liver. After curative treatment intestinal granulomas undergo a relatively more rapid resorption, although the general pattern of collagen degradation apparently does not differ from that observed in the liver. Tendency to form scattered, usually isolated granulomas that are only mildly fibrogenic, coupled with a well-balanced process of resorption appear as the explanation why intestinal fibrosis is not an outstanding feature of schistosomiasis as it is in the liver.
publishDate 1992
dc.date.none.fl_str_mv 1992-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100005
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761992000100005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.87 n.1 1992
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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