Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex

Detalhes bibliográficos
Autor(a) principal: Toihir,Al-Habib Omar Said
Data de Publicação: 2011
Outros Autores: Rasolofo,Voahangy, Andrianarisoa,Samuel Hermas, Ranjalahy,Gabriel Marie, Ramarokoto,Herimanana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000600022
Resumo: The performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold standard. The results presented here indicate that this kit has excellent sensitivity (100%) and specificity (100%) compared to standard biochemical detection and can be easily used for the rapid identification of M. tuberculosis complex.
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spelling Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complexMycobacterium tuberculosisAg MPT64MadagascarThe performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold standard. The results presented here indicate that this kit has excellent sensitivity (100%) and specificity (100%) compared to standard biochemical detection and can be easily used for the rapid identification of M. tuberculosis complex.Instituto Oswaldo Cruz, Ministério da Saúde2011-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000600022Memórias do Instituto Oswaldo Cruz v.106 n.6 2011reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762011000600022info:eu-repo/semantics/openAccessToihir,Al-Habib Omar SaidRasolofo,VoahangyAndrianarisoa,Samuel HermasRanjalahy,Gabriel MarieRamarokoto,Herimananaeng2020-04-25T17:51:04Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:17:52.012Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
title Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
spellingShingle Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
Toihir,Al-Habib Omar Said
Mycobacterium tuberculosis
Ag MPT64
Madagascar
title_short Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
title_full Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
title_fullStr Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
title_full_unstemmed Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
title_sort Validation of an immunochromatographic assay kit for the identification of the Mycobacterium tuberculosis complex
author Toihir,Al-Habib Omar Said
author_facet Toihir,Al-Habib Omar Said
Rasolofo,Voahangy
Andrianarisoa,Samuel Hermas
Ranjalahy,Gabriel Marie
Ramarokoto,Herimanana
author_role author
author2 Rasolofo,Voahangy
Andrianarisoa,Samuel Hermas
Ranjalahy,Gabriel Marie
Ramarokoto,Herimanana
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Toihir,Al-Habib Omar Said
Rasolofo,Voahangy
Andrianarisoa,Samuel Hermas
Ranjalahy,Gabriel Marie
Ramarokoto,Herimanana
dc.subject.por.fl_str_mv Mycobacterium tuberculosis
Ag MPT64
Madagascar
topic Mycobacterium tuberculosis
Ag MPT64
Madagascar
dc.description.none.fl_txt_mv The performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold standard. The results presented here indicate that this kit has excellent sensitivity (100%) and specificity (100%) compared to standard biochemical detection and can be easily used for the rapid identification of M. tuberculosis complex.
description The performance of the immunochromatographic assay, SD BIOLINE TB Ag MPT64 RAPID®, was evaluated in Madagascar. Using mouse anti-MPT64 monoclonal antibodies for rapid discrimination between the Mycobacterium tuberculosis complex and nontuberculous mycobacteria, the kit was tested on mycobacteria and other pathogens using conventional methods as the gold standard. The results presented here indicate that this kit has excellent sensitivity (100%) and specificity (100%) compared to standard biochemical detection and can be easily used for the rapid identification of M. tuberculosis complex.
publishDate 2011
dc.date.none.fl_str_mv 2011-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000600022
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000600022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762011000600022
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.106 n.6 2011
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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