Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies

Detalhes bibliográficos
Autor(a) principal: Andrade-Narvaez,Fernando J
Data de Publicação: 2016
Outros Autores: Loría-Cervera,Elsy Nalleli, Sosa-Bibiano,Erika I, Van Wynsberghe,Nicole R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599
Resumo: American cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following: (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage.
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spelling Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studiesAmerican cutaneous leishmaniasisasymptomatic infectionAmerican cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following: (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage.Instituto Oswaldo Cruz, Ministério da Saúde2016-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599Memórias do Instituto Oswaldo Cruz v.111 n.10 2016reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/0074-02760160138info:eu-repo/semantics/openAccessAndrade-Narvaez,Fernando JLoría-Cervera,Elsy NalleliSosa-Bibiano,Erika IVan Wynsberghe,Nicole Reng2020-04-25T17:52:23Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:21:11.426Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
title Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
spellingShingle Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
Andrade-Narvaez,Fernando J
American cutaneous leishmaniasis
asymptomatic infection
title_short Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
title_full Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
title_fullStr Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
title_full_unstemmed Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
title_sort Asymptomatic infection with American cutaneous leishmaniasis: epidemiological and immunological studies
author Andrade-Narvaez,Fernando J
author_facet Andrade-Narvaez,Fernando J
Loría-Cervera,Elsy Nalleli
Sosa-Bibiano,Erika I
Van Wynsberghe,Nicole R
author_role author
author2 Loría-Cervera,Elsy Nalleli
Sosa-Bibiano,Erika I
Van Wynsberghe,Nicole R
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade-Narvaez,Fernando J
Loría-Cervera,Elsy Nalleli
Sosa-Bibiano,Erika I
Van Wynsberghe,Nicole R
dc.subject.por.fl_str_mv American cutaneous leishmaniasis
asymptomatic infection
topic American cutaneous leishmaniasis
asymptomatic infection
dc.description.none.fl_txt_mv American cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following: (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage.
description American cutaneous leishmaniasis (ACL) is a major public health problem caused by vector-borne protozoan intracellular parasites from the genus Leishmania, subgenera Viannia and Leishmania. Asymptomatic infection is the most common outcome after Leishmania inoculation. There is incomplete knowledge of the biological processes explaining the absence of signs or symptoms in most cases while other cases present a variety of clinical findings. Most studies of asymptomatic infection have been conducted in areas of endemic visceral leishmaniasis. In contrast, asymptomatic ACL infection has been neglected. This review is focused on the following: (1) epidemiological studies supporting the existence of asymptomatic ACL infection and (2) immunological studies conducted to understand the mechanisms responsible for controlling the parasite and avoiding tissue damage.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762016001000599
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0074-02760160138
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.111 n.10 2016
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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