Factors associated with the severity of transfusion reactions that occurred in a teaching hospital, in the city of São Paulo, between 2007-2019

• Autor(a) principal: Grandi, João Luiz
• Data de Publicação: 2021
• Outros Autores: Catherina Nema Areco, Kelsy, Chiba, Akemi, Melca Barros de Oliveira, Maria, Aparecida Barbosa, Dulce
• Tipo de documento: Artigo
• Idioma: por; eng
• Título da fonte: Vigilância Sanitária em Debate
• Texto Completo: https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1448
• topic: Risk Management; Transfusion Reaction; Patient Safety; Blood Safety; Health Surveillance; gestión de riesgos; reacción a la transfusión; seguridad del paciente; seguridad de la sangre;, vigilancia sanitaria; Gestão de Riscos; Reação Transfusional; Segurança do Paciente; Segurança do Sangue; Vigilância Sanitária

Introduction: Transfusion reactions can have serious consequences for recipients of blood  components. Objective: To analyze the proportion of adverse reactions regarding the degree of severity observed in transfusions and to identify factors associated with the severity of immediate transfusion incidents. Method: This is a retrospective longitudinal study of epidemiological evaluation regarding the immediate transfusion reactions that occurred between 2007 and 2019 in a teaching hospital. Results: Of the 332,222 blood transfusions administered in the period, 1,448 notifications of immediate transfusion reactions were reported. The average annual incidence of transfusion reaction was 4.4 per thousand. Moderate and severe reactions represent 13.5% of all events. Hemoglobin and hematocrit did not present regular distribution (p ≤ 0.001). Conclusion: The data analysis made it possible to evaluate the   transfusion practice at the institution, which proved to be adequate and reflected the constant efforts to feed the Brazilian System of Hemovigilance. The severity of the reactions has been associated with inpatient units, which are more severe in the critical and semi-critical care units. However, the study showed that mild reactions should not be neglected.