Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest

Detalhes bibliográficos
Autor(a) principal: Soares, Daniela Fernandes Ramos
Data de Publicação: 2008
Outros Autores: Leitão, Gilda Guimarães, Costa, Fernanda das Neves, Abreu, Lisandra Ferreira de, Villarreal, Javier Vargas, Leitão, Suzana Guimarães, Fernández, Salvador Luis Said y, Silva, Pedro Eduardo Almeida da
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FURG (RI FURG)
Texto Completo: http://repositorio.furg.br/handle/1/2588
Resumo: Thirty-six plant extracts from the brazilian Atlantic Forest were tested for their antimycobacterial activity against Mycobacterium tuberculosis H37Rv and M. kansasii, using the method REMA in seriate concentrations of 100 to 0.20 μg/mL. Among the thirty six extracts tested, five were active against M. tuberculosis, and three of these extracts also showed activity against M. kansasii. Cytotoxicity test with VERO cells was performed with the five extracts active against M. tuberculosis. Only the extract of Peschiera affinis was identified as non-toxic in the concentration of 100μg/mL.
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spelling Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic ForestAnálise da atividade antimicobacteriana de 36 extratos vegetais da Mata Atlântica brasileiraMycobacterium tuberculosisMycobacterium kansasiiPlant extracts/antimycobacterial activityAntimycobacterialsCytotoxicityExtratos vegetais/atividade antimicobacterianaAntimicobacterianosCitotoxicidadeThirty-six plant extracts from the brazilian Atlantic Forest were tested for their antimycobacterial activity against Mycobacterium tuberculosis H37Rv and M. kansasii, using the method REMA in seriate concentrations of 100 to 0.20 μg/mL. Among the thirty six extracts tested, five were active against M. tuberculosis, and three of these extracts also showed activity against M. kansasii. Cytotoxicity test with VERO cells was performed with the five extracts active against M. tuberculosis. Only the extract of Peschiera affinis was identified as non-toxic in the concentration of 100μg/mL.Trinta e seis extratos vegetais originários da Mata Atlântica foram testados quanto à sua atividade antimicobacteriana frente ao M. tuberculosis H37Rv e M. kansasii, utilizando o método REMA em concentrações seriadas de 100 a 0,20 μg/mL. Dentre os trinta e seis extratos testados, cinco mostraram atividade frente ao M.tuberculosis, e destes apenas, três mostraram atividade ao M. kansasii, que apresentou susceptibilidade a outros dez. O teste de citotoxicidade com células VERO foi realizado com os cinco extratos ativos frente ao M. tuberculosis em que identificou-se a não toxicidade em apenas um extrato (Peschiera affinis) na concentração de 100 μg/mL.2012-09-24T23:55:29Z2012-09-24T23:55:29Z2008info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfRAMOS, Daniela Fernandes. et al. Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest. Revista Brasileira de Ciências Farmacêuticas, v. 44, n. 4, p. 669-674, 2008. Disponível em: <http://www.scielo.br/pdf/rbcf/v44n4/v44n4a13.pdf >. Acesso em: 17 set. 2012.http://repositorio.furg.br/handle/1/2588engSoares, Daniela Fernandes RamosLeitão, Gilda GuimarãesCosta, Fernanda das NevesAbreu, Lisandra Ferreira deVillarreal, Javier VargasLeitão, Suzana GuimarãesFernández, Salvador Luis Said ySilva, Pedro Eduardo Almeida dainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FURG (RI FURG)instname:Universidade Federal do Rio Grande (FURG)instacron:FURG2021-01-19T01:05:17Zoai:repositorio.furg.br:1/2588Repositório InstitucionalPUBhttps://repositorio.furg.br/oai/request || http://200.19.254.174/oai/requestopendoar:2021-01-19T01:05:17Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)false
dc.title.none.fl_str_mv Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
Análise da atividade antimicobacteriana de 36 extratos vegetais da Mata Atlântica brasileira
title Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
spellingShingle Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
Soares, Daniela Fernandes Ramos
Mycobacterium tuberculosis
Mycobacterium kansasii
Plant extracts/antimycobacterial activity
Antimycobacterials
Cytotoxicity
Extratos vegetais/atividade antimicobacteriana
Antimicobacterianos
Citotoxicidade
title_short Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
title_full Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
title_fullStr Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
title_full_unstemmed Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
title_sort Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest
author Soares, Daniela Fernandes Ramos
author_facet Soares, Daniela Fernandes Ramos
Leitão, Gilda Guimarães
Costa, Fernanda das Neves
Abreu, Lisandra Ferreira de
Villarreal, Javier Vargas
Leitão, Suzana Guimarães
Fernández, Salvador Luis Said y
Silva, Pedro Eduardo Almeida da
author_role author
author2 Leitão, Gilda Guimarães
Costa, Fernanda das Neves
Abreu, Lisandra Ferreira de
Villarreal, Javier Vargas
Leitão, Suzana Guimarães
Fernández, Salvador Luis Said y
Silva, Pedro Eduardo Almeida da
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Soares, Daniela Fernandes Ramos
Leitão, Gilda Guimarães
Costa, Fernanda das Neves
Abreu, Lisandra Ferreira de
Villarreal, Javier Vargas
Leitão, Suzana Guimarães
Fernández, Salvador Luis Said y
Silva, Pedro Eduardo Almeida da
dc.subject.por.fl_str_mv Mycobacterium tuberculosis
Mycobacterium kansasii
Plant extracts/antimycobacterial activity
Antimycobacterials
Cytotoxicity
Extratos vegetais/atividade antimicobacteriana
Antimicobacterianos
Citotoxicidade
topic Mycobacterium tuberculosis
Mycobacterium kansasii
Plant extracts/antimycobacterial activity
Antimycobacterials
Cytotoxicity
Extratos vegetais/atividade antimicobacteriana
Antimicobacterianos
Citotoxicidade
description Thirty-six plant extracts from the brazilian Atlantic Forest were tested for their antimycobacterial activity against Mycobacterium tuberculosis H37Rv and M. kansasii, using the method REMA in seriate concentrations of 100 to 0.20 μg/mL. Among the thirty six extracts tested, five were active against M. tuberculosis, and three of these extracts also showed activity against M. kansasii. Cytotoxicity test with VERO cells was performed with the five extracts active against M. tuberculosis. Only the extract of Peschiera affinis was identified as non-toxic in the concentration of 100μg/mL.
publishDate 2008
dc.date.none.fl_str_mv 2008
2012-09-24T23:55:29Z
2012-09-24T23:55:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv RAMOS, Daniela Fernandes. et al. Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest. Revista Brasileira de Ciências Farmacêuticas, v. 44, n. 4, p. 669-674, 2008. Disponível em: <http://www.scielo.br/pdf/rbcf/v44n4/v44n4a13.pdf >. Acesso em: 17 set. 2012.
http://repositorio.furg.br/handle/1/2588
identifier_str_mv RAMOS, Daniela Fernandes. et al. Investigation of the antimycobacterial activity of 36 plant extracts from the Brazilian Atlantic Forest. Revista Brasileira de Ciências Farmacêuticas, v. 44, n. 4, p. 669-674, 2008. Disponível em: <http://www.scielo.br/pdf/rbcf/v44n4/v44n4a13.pdf >. Acesso em: 17 set. 2012.
url http://repositorio.furg.br/handle/1/2588
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da FURG (RI FURG)
instname:Universidade Federal do Rio Grande (FURG)
instacron:FURG
instname_str Universidade Federal do Rio Grande (FURG)
instacron_str FURG
institution FURG
reponame_str Repositório Institucional da FURG (RI FURG)
collection Repositório Institucional da FURG (RI FURG)
repository.name.fl_str_mv Repositório Institucional da FURG (RI FURG) - Universidade Federal do Rio Grande (FURG)
repository.mail.fl_str_mv
_version_ 1813187247081521152

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