A narrative review of the literature on the treatment of multiple sclerosis

• Autor(a) principal: Pereira Levada, Leonardo
• Data de Publicação: 2024
• Outros Autores: De Souza Barbosa, Júlia Letícia, Neto de Souza Ferreira, Ezo, Martins Marinho, Amanda, Fonseca Ferraz, Luísa, Castro Milazzo, Brendha, Naves Dias Azevedo, João Antônio, Ferraz Medeiros, Rebeca, Catarina Belizio da Silva, Késsia, Cristina Teixeira, Carla, Freitas Santos, Amanda, Caroline Marinho Dantas, Lorena, de Medeiros Jardim Pacheco, Gabriel, Railla Barbalho Alves, Anna, Aguiar Alencar de Oliveira, Victor
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1765
• topic: Doença de Parkinson; Neurodegeneração; Terapias Emergentes; Tecnologias de Monitoramento; Ensaios Clínicos; Parkinson's Disease; Neurodegeneration; Emerging Therapies; Monitoring Technologies; Clinical Trials

Parkinson's disease (PD) is a complex neurodegenerative condition characterized by debilitating motor and non-motor symptoms resulting from the progressive loss of dopaminergic neurons. This text reviews a variety of emerging therapeutic strategies for PD, ranging from stem cell-based therapies to novel pharmacological approaches, such as the use of antidiabetic agents and modulation of the kynurenine enzymatic system. While these approaches offer hope for halting disease progression, they face ethical, technical, and clinical challenges that need to be addressed to ensure their clinical success. Additionally, technologies like wearables and motion analysis offer innovative ways to monitor and optimize PD treatment, though they also present standardization and correlation challenges with other disease markers. Ultimately, a multidisciplinary and careful approach, coupled with robust clinical trials, is essential to realize the full potential of these interventions and improve the quality of life for patients with PD and other neurodegenerative conditions.