Current perspectives on Polycystic Ovary Syndrome: diagnostic and therapeutic approaches

• Autor(a) principal: Vytor Cardoso Nobre, Paulo
• Data de Publicação: 2024
• Outros Autores: de Araújo Alves Júnior , Josivaldo, Baracho Macena, Leopoldo, Saleme Moreira Vasconcelos da Rocha, Manuela, Erika Neumann Costa , Katherine, Raquel Batista Melo , Thereza, Silvina Rodrigues Silva, Lara, Toledo Calheiros Nobre Sampaio, Mariana, Victor Santos Meneses , João, Inês Costa Cordeiro , Karine, César Guimarães Bancilon, Carlos, Silveira da Silva, Liliane
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Brazilian Journal of Implantology and Health Sciences
• Texto Completo: https://bjihs.emnuvens.com.br/bjihs/article/view/1759
• topic: diagnóstico; tratamento; manejo; síndrome do ovário policístico; diagnosis; treatment; management; polycystic ovary syndrome

Introduction: Polycystic ovarian syndrome (PCOS) is a complex endocrine condition characterized by ovarian dysfunction and androgen hypersecretion. Objective: To evaluate the pathophysiological bases associated with polycystic ovary syndrome, highlighting its multifactorial complexity, and to examine therapeutic strategies. Methodology: This is a bibliographic review that included original articles and systematic reviews in English and Portuguese, which addressed pathophysiological aspects and PCOS management, published between 2016 and 2024, selected from the PubMed, Scopus and SciELO databases. After careful selection, 18 articles were chosen to compose this bibliographic review. Results: PCOS is influenced by epigenetic mechanisms, exposure to toxic compounds, hyperinsulinemia and hyperandrogenism, which directly affect ovulation and metabolism. Obesity also contributes to PCOS. Treatment involves lifestyle changes and medications to control symptoms and restore ovulation. Considerations: PCOS is a complex condition, involving genetic, epigenetic, environmental and metabolic factors. Treatment aims to address underlying symptoms and mechanisms, with lifestyle changes and individualized pharmacological therapy. A multidisciplinary approach is essential to improve patients' quality of life.