BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon
Autor(a) principal: | |
---|---|
Data de Publicação: | 2020 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/4217 |
Resumo: | Abstract: In 2018, 208,619 new cases of leprosy were reported to the World Health Organization (WHO). Of these, 30,957 occurred in the Americas region and 28,660 (92.6% of the total in the Americas) were reported in Brazil. This study aimed to show the reality of the profile of a population in an endemic leprosy area in northern Brazil in relation to age, gender, and bacillus Calmette–Guérin (BCG) vaccination status through the collection of data in the field with the evaluation of the study individuals, who were recruited by spontaneous demand. A total of 405 individuals participated in the study, with 100 multibacillary, 57 paucibacillary, and 248 healthy contacts. A relationship was observed between the occurrence of the disease, as well as the multibacillary form with the largest age group. The male gender was associated with leprosy per se, with the multibacillary form and was the largest representative of the group that was not vaccinated once. BCG vaccination was effective both in protecting against leprosy per se and in the multibacillary form. These results are limited by sample size, may not be conclusive, and will need further confirmation in a larger cohort. |
id |
IEC-2_0eb876314a43bfe9c1fe6f1a5f95305c |
---|---|
oai_identifier_str |
oai:patua.iec.gov.br:iec/4217 |
network_acronym_str |
IEC-2 |
network_name_str |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
repository_id_str |
|
spelling |
Lima, Luana Nepomuceno Gondim CostaPaz, Jasna Letícia PintoSilvestre, Maria do Perpetuo Socorro AmadorMoura, Letícia SiqueiraFurlaneto, Ismari PeriniLima, Karla Valéria Batista2021-01-25T13:37:34Z2021-01-25T13:37:34Z2020LIMA, Luana Nepomuceno Gondim Costa et al. BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon. Infectious Disease Reports, v. 12, n. 3, p. 97-104, Dec. 2020.2036-7430https://patua.iec.gov.br/handle/iec/421710.3390/idr12030019Abstract: In 2018, 208,619 new cases of leprosy were reported to the World Health Organization (WHO). Of these, 30,957 occurred in the Americas region and 28,660 (92.6% of the total in the Americas) were reported in Brazil. This study aimed to show the reality of the profile of a population in an endemic leprosy area in northern Brazil in relation to age, gender, and bacillus Calmette–Guérin (BCG) vaccination status through the collection of data in the field with the evaluation of the study individuals, who were recruited by spontaneous demand. A total of 405 individuals participated in the study, with 100 multibacillary, 57 paucibacillary, and 248 healthy contacts. A relationship was observed between the occurrence of the disease, as well as the multibacillary form with the largest age group. The male gender was associated with leprosy per se, with the multibacillary form and was the largest representative of the group that was not vaccinated once. BCG vaccination was effective both in protecting against leprosy per se and in the multibacillary form. These results are limited by sample size, may not be conclusive, and will need further confirmation in a larger cohort.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil / Universidade do Estado do Pará. Program in Parasitic Biology in the Amazon. Belém, PA, Brasil.Universidade do Estado do Pará. Program in Parasitic Biology in the Amazon. Belém, PA, BrasilMinistério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Centro Universitário do Estado do Pará. Department of Medicine. Belém, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil / Universidade do Estado do Pará. Program in Parasitic Biology in the Amazon. Belém, PA, Brasil.engMDPIBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazoninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleHanseníaseMycobacterium leprae / patogenicidadeMycobacterium bovis / patogenicidadeVacina BCGCobertura Vacinal / estatística & dados numéricosinfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon.pdfBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon.pdfapplication/pdf268469https://patua.iec.gov.br/bitstreams/590cc920-295f-4ddd-be55-cfb74cd511ec/download4496b6a4073cf95437ad53ea58cbdbe4MD51TEXTBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon.pdf.txtBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon.pdf.txtExtracted texttext/plain29394https://patua.iec.gov.br/bitstreams/ecb95efb-3f37-44ff-aaa5-b4bbffd0fe93/download43db46855c45e3ddca65f71881a6949eMD55THUMBNAILBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon.pdf.jpgBCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon.pdf.jpgGenerated Thumbnailimage/jpeg5431https://patua.iec.gov.br/bitstreams/a0f0b0a3-0ea3-4bc9-be66-aa91d74ede3e/download1053ab3fdd1d24362564665cc1328689MD56LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/0fd87160-8a09-4eef-b28e-1dc3b58c2df4/download11832eea31b16df8613079d742d61793MD52iec/42172022-10-20 21:06:21.484oai:patua.iec.gov.br:iec/4217https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T21:06:21Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)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 |
dc.title.pt_BR.fl_str_mv |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
title |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
spellingShingle |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon Lima, Luana Nepomuceno Gondim Costa Hanseníase Mycobacterium leprae / patogenicidade Mycobacterium bovis / patogenicidade Vacina BCG Cobertura Vacinal / estatística & dados numéricos |
title_short |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
title_full |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
title_fullStr |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
title_full_unstemmed |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
title_sort |
BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon |
author |
Lima, Luana Nepomuceno Gondim Costa |
author_facet |
Lima, Luana Nepomuceno Gondim Costa Paz, Jasna Letícia Pinto Silvestre, Maria do Perpetuo Socorro Amador Moura, Letícia Siqueira Furlaneto, Ismari Perini Lima, Karla Valéria Batista |
author_role |
author |
author2 |
Paz, Jasna Letícia Pinto Silvestre, Maria do Perpetuo Socorro Amador Moura, Letícia Siqueira Furlaneto, Ismari Perini Lima, Karla Valéria Batista |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Lima, Luana Nepomuceno Gondim Costa Paz, Jasna Letícia Pinto Silvestre, Maria do Perpetuo Socorro Amador Moura, Letícia Siqueira Furlaneto, Ismari Perini Lima, Karla Valéria Batista |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Hanseníase Mycobacterium leprae / patogenicidade Mycobacterium bovis / patogenicidade Vacina BCG Cobertura Vacinal / estatística & dados numéricos |
topic |
Hanseníase Mycobacterium leprae / patogenicidade Mycobacterium bovis / patogenicidade Vacina BCG Cobertura Vacinal / estatística & dados numéricos |
description |
Abstract: In 2018, 208,619 new cases of leprosy were reported to the World Health Organization (WHO). Of these, 30,957 occurred in the Americas region and 28,660 (92.6% of the total in the Americas) were reported in Brazil. This study aimed to show the reality of the profile of a population in an endemic leprosy area in northern Brazil in relation to age, gender, and bacillus Calmette–Guérin (BCG) vaccination status through the collection of data in the field with the evaluation of the study individuals, who were recruited by spontaneous demand. A total of 405 individuals participated in the study, with 100 multibacillary, 57 paucibacillary, and 248 healthy contacts. A relationship was observed between the occurrence of the disease, as well as the multibacillary form with the largest age group. The male gender was associated with leprosy per se, with the multibacillary form and was the largest representative of the group that was not vaccinated once. BCG vaccination was effective both in protecting against leprosy per se and in the multibacillary form. These results are limited by sample size, may not be conclusive, and will need further confirmation in a larger cohort. |
publishDate |
2020 |
dc.date.issued.fl_str_mv |
2020 |
dc.date.accessioned.fl_str_mv |
2021-01-25T13:37:34Z |
dc.date.available.fl_str_mv |
2021-01-25T13:37:34Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
LIMA, Luana Nepomuceno Gondim Costa et al. BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon. Infectious Disease Reports, v. 12, n. 3, p. 97-104, Dec. 2020. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/4217 |
dc.identifier.issn.-.fl_str_mv |
2036-7430 |
dc.identifier.doi.-.fl_str_mv |
10.3390/idr12030019 |
identifier_str_mv |
LIMA, Luana Nepomuceno Gondim Costa et al. BCG vaccination status, age, and gender as risk factors for leprosy in endemic areas in the brazilian amazon. Infectious Disease Reports, v. 12, n. 3, p. 97-104, Dec. 2020. 2036-7430 10.3390/idr12030019 |
url |
https://patua.iec.gov.br/handle/iec/4217 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Digital do Instituto Evandro Chagas (Patuá) instname:Instituto Evandro Chagas (IEC) instacron:IEC |
instname_str |
Instituto Evandro Chagas (IEC) |
instacron_str |
IEC |
institution |
IEC |
reponame_str |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
collection |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
bitstream.url.fl_str_mv |
https://patua.iec.gov.br/bitstreams/590cc920-295f-4ddd-be55-cfb74cd511ec/download https://patua.iec.gov.br/bitstreams/ecb95efb-3f37-44ff-aaa5-b4bbffd0fe93/download https://patua.iec.gov.br/bitstreams/a0f0b0a3-0ea3-4bc9-be66-aa91d74ede3e/download https://patua.iec.gov.br/bitstreams/0fd87160-8a09-4eef-b28e-1dc3b58c2df4/download |
bitstream.checksum.fl_str_mv |
4496b6a4073cf95437ad53ea58cbdbe4 43db46855c45e3ddca65f71881a6949e 1053ab3fdd1d24362564665cc1328689 11832eea31b16df8613079d742d61793 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC) |
repository.mail.fl_str_mv |
clariceneta@iec.gov.br || Biblioteca@iec.gov.br |
_version_ |
1809190033393975296 |