Longitudinal study of rotavirus infections among children from Belém, Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 1989 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/939 |
Resumo: | From December 1982 to March 1986 a group of 80 children between O and 3years old who lived in the peripheral area of Belém, Brazil, were followed up for episodes of diarrhoea. A total of 441 diarrhoeal episodes were recorded and 36 (8.2 percent) were associated with rotavirus. This agent was the only pathogen in 50 percent of rotavirus-related episodes of acute diarrhoea,and strains were characterized by analysis of RNA in polyacrylamide gels. Forty-one belnged to subgroup ll (long pattern) and five to subgroup I. Reinfections by rotavirus were noted in 12 children involving either the same or different subgroups. Ten distinct electrophoretypes were detected in the study period and the predominant one had the ' 1N2L' profile. The cumulative age-specific attack rate for diarrhoea reached 2'8 by the end of the first year of life; a frequency of 2.3 episodes of diarrhoea per child per year was observed throughout the complete investigation, In comparing the age-specific attack rates for diarrhoea between breast-fed and bottle-fed children, a peak at 6 months of age was noted in the former, and at 1 month in the latter. A comparison by Fischer's exact test (P = 0'21) provided no evidence for protection against clinical rotavirus disease by maternal milk. By the same test, however (P = 0'021), we found significant evidence that early rotavirus infections were more likely to be asymptomatic and that infections after 4 months were more likely to be symptomatic. The clinical picture in children with rotavirus-related diarrhoea was more severe than in those suffering from cute diarrhoea due to another agent. |
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Linhares, Alexandre da CostaGabbay, Yvone BenchimolFreitas, Ronaldo Barros deRosa, Elizabeth Salbé Travassos daMascarenhas, Joana D'Arc Pereira2016-01-26T11:39:49Z2016-01-26T11:39:49Z1989LINHARES, Alexandre da Costa et al. Longitudinal study of rotavirus infections among children from Belém, Brazil. Epidemiology and Infection, v. 102, n. 1, p. 129-145, Feb 1989.0950-2688https://patua.iec.gov.br/handle/iec/939From December 1982 to March 1986 a group of 80 children between O and 3years old who lived in the peripheral area of Belém, Brazil, were followed up for episodes of diarrhoea. A total of 441 diarrhoeal episodes were recorded and 36 (8.2 percent) were associated with rotavirus. This agent was the only pathogen in 50 percent of rotavirus-related episodes of acute diarrhoea,and strains were characterized by analysis of RNA in polyacrylamide gels. Forty-one belnged to subgroup ll (long pattern) and five to subgroup I. Reinfections by rotavirus were noted in 12 children involving either the same or different subgroups. Ten distinct electrophoretypes were detected in the study period and the predominant one had the ' 1N2L' profile. The cumulative age-specific attack rate for diarrhoea reached 2'8 by the end of the first year of life; a frequency of 2.3 episodes of diarrhoea per child per year was observed throughout the complete investigation, In comparing the age-specific attack rates for diarrhoea between breast-fed and bottle-fed children, a peak at 6 months of age was noted in the former, and at 1 month in the latter. A comparison by Fischer's exact test (P = 0'21) provided no evidence for protection against clinical rotavirus disease by maternal milk. By the same test, however (P = 0'021), we found significant evidence that early rotavirus infections were more likely to be asymptomatic and that infections after 4 months were more likely to be symptomatic. The clinical picture in children with rotavirus-related diarrhoea was more severe than in those suffering from cute diarrhoea due to another agent.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.Ministério da Saúde. Fundação Serviços de Saúde Pública. Instituto Evandro Chagas. Belém, PA, Brasil.application/pdfengCambridge University PressLongitudinal study of rotavirus infections among children from Belém, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRotavirus / classificaçãoInfecções por Rotavirus / epidemiologiaEstudos LongitudinaisDiarréia Infantil / epidemiologiaDiarréia Infantil / microbiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALLongitudinal study of rotavirus infections among children from Belém, Brazil .pdfapplication/pdf2283155https://patua.iec.gov.br/bitstreams/35fc94f6-05cf-4455-8d11-e161cb0423ba/download69896ef2c5390d001bf3334f99a0eb59MD51TEXTfile_1.pdf.txtfile_1.pdf.txtExtracted texttext/plain40397https://patua.iec.gov.br/bitstreams/d4c3f531-a466-482c-bd03-c9b6fc3d43c3/download97aa85b91d70ffa43a6b70ec420e41ddMD52Longitudinal study of rotavirus infections among children from Belém, Brazil .pdf.txtLongitudinal study of rotavirus infections among children from Belém, Brazil .pdf.txtExtracted texttext/plain41491https://patua.iec.gov.br/bitstreams/c60f6e72-6b85-494d-8f7a-72346cb01e28/download2829bf7ba8d02b6e8375356a04d7d073MD56THUMBNAILLongitudinal study of rotavirus infections among children from Belém, Brazil .pdf.jpgLongitudinal study of rotavirus infections among children from Belém, Brazil .pdf.jpgGenerated Thumbnailimage/jpeg5685https://patua.iec.gov.br/bitstreams/b6c2a8a8-9c96-4e21-bcfa-f0fe6f29bcad/download1911ac7a45e4c994e64a5b242ae5ab77MD57LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/1585ee36-85f8-4c2b-b444-c633cf867735/download11832eea31b16df8613079d742d61793MD55iec/9392022-10-20 21:13:03.237oai:patua.iec.gov.br:iec/939https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T21:13:03Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)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 |
dc.title.pt_BR.fl_str_mv |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
title |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
spellingShingle |
Longitudinal study of rotavirus infections among children from Belém, Brazil Linhares, Alexandre da Costa Rotavirus / classificação Infecções por Rotavirus / epidemiologia Estudos Longitudinais Diarréia Infantil / epidemiologia Diarréia Infantil / microbiologia |
title_short |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
title_full |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
title_fullStr |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
title_full_unstemmed |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
title_sort |
Longitudinal study of rotavirus infections among children from Belém, Brazil |
author |
Linhares, Alexandre da Costa |
author_facet |
Linhares, Alexandre da Costa Gabbay, Yvone Benchimol Freitas, Ronaldo Barros de Rosa, Elizabeth Salbé Travassos da Mascarenhas, Joana D'Arc Pereira |
author_role |
author |
author2 |
Gabbay, Yvone Benchimol Freitas, Ronaldo Barros de Rosa, Elizabeth Salbé Travassos da Mascarenhas, Joana D'Arc Pereira |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Linhares, Alexandre da Costa Gabbay, Yvone Benchimol Freitas, Ronaldo Barros de Rosa, Elizabeth Salbé Travassos da Mascarenhas, Joana D'Arc Pereira |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Rotavirus / classificação Infecções por Rotavirus / epidemiologia Estudos Longitudinais |
topic |
Rotavirus / classificação Infecções por Rotavirus / epidemiologia Estudos Longitudinais Diarréia Infantil / epidemiologia Diarréia Infantil / microbiologia |
dc.subject.decsSecondary.pt_BR.fl_str_mv |
Diarréia Infantil / epidemiologia Diarréia Infantil / microbiologia |
description |
From December 1982 to March 1986 a group of 80 children between O and 3years old who lived in the peripheral area of Belém, Brazil, were followed up for episodes of diarrhoea. A total of 441 diarrhoeal episodes were recorded and 36 (8.2 percent) were associated with rotavirus. This agent was the only pathogen in 50 percent of rotavirus-related episodes of acute diarrhoea,and strains were characterized by analysis of RNA in polyacrylamide gels. Forty-one belnged to subgroup ll (long pattern) and five to subgroup I. Reinfections by rotavirus were noted in 12 children involving either the same or different subgroups. Ten distinct electrophoretypes were detected in the study period and the predominant one had the ' 1N2L' profile. The cumulative age-specific attack rate for diarrhoea reached 2'8 by the end of the first year of life; a frequency of 2.3 episodes of diarrhoea per child per year was observed throughout the complete investigation, In comparing the age-specific attack rates for diarrhoea between breast-fed and bottle-fed children, a peak at 6 months of age was noted in the former, and at 1 month in the latter. A comparison by Fischer's exact test (P = 0'21) provided no evidence for protection against clinical rotavirus disease by maternal milk. By the same test, however (P = 0'021), we found significant evidence that early rotavirus infections were more likely to be asymptomatic and that infections after 4 months were more likely to be symptomatic. The clinical picture in children with rotavirus-related diarrhoea was more severe than in those suffering from cute diarrhoea due to another agent. |
publishDate |
1989 |
dc.date.issued.fl_str_mv |
1989 |
dc.date.accessioned.fl_str_mv |
2016-01-26T11:39:49Z |
dc.date.available.fl_str_mv |
2016-01-26T11:39:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
LINHARES, Alexandre da Costa et al. Longitudinal study of rotavirus infections among children from Belém, Brazil. Epidemiology and Infection, v. 102, n. 1, p. 129-145, Feb 1989. |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/939 |
dc.identifier.issn.-.fl_str_mv |
0950-2688 |
identifier_str_mv |
LINHARES, Alexandre da Costa et al. Longitudinal study of rotavirus infections among children from Belém, Brazil. Epidemiology and Infection, v. 102, n. 1, p. 129-145, Feb 1989. 0950-2688 |
url |
https://patua.iec.gov.br/handle/iec/939 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Cambridge University Press |
publisher.none.fl_str_mv |
Cambridge University Press |
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Instituto Evandro Chagas (IEC) |
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IEC |
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IEC |
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Repositório Digital do Instituto Evandro Chagas (Patuá) |
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Repositório Digital do Instituto Evandro Chagas (Patuá) |
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