Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report

Detalhes bibliográficos
Autor(a) principal: Rosário, Mateus Santana do
Data de Publicação: 2016
Outros Autores: Jesus, Pedro Antonio Pereira de, Vasilakis, Nikos, Farias, Daniel Santana, Novaes, Marco Antônio Caires, Rodrigues, Sueli Guerreiro, Martins, Lívia Caricio, Vasconcelos, Pedro Fernando da Costa, Ko, Albert Icksang, Alcantara, Luiz Carlos Júnior, Siqueira, Isadora Cristina de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
Texto Completo: https://patua.iec.gov.br/handle/iec/2468
Resumo: Zika virus (ZIKV) is an emerging flavivirus, which has caused a widespread outbreak in the Americas. Shortly after its introduction in 2015, a cluster of cases with Guillain-Barré syndrome was detected in Brazil. Herein, we describe two cases from the city of Salvador, who developed ascending paresis after an acute exanthematous illness. The patients were admitted to the intensive care unit with tetraparesis and cranial nerve palsy, which resolved after intravenous administration of human immunoglobulin. Serological evaluation detected IgM-specific ZIKV antibodies. In regions of Zika virus transmission, health-care workers must be aware of the potential severe neurological complications associated with ZIKV infection and be prepared to provide prompt diagnosis, treatment, and supportive care.
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spelling Rosário, Mateus Santana doJesus, Pedro Antonio Pereira deVasilakis, NikosFarias, Daniel SantanaNovaes, Marco Antônio CairesRodrigues, Sueli GuerreiroMartins, Lívia CaricioVasconcelos, Pedro Fernando da CostaKo, Albert IcksangAlcantara, Luiz Carlos JúniorSiqueira, Isadora Cristina de2017-02-01T19:17:51Z2017-02-01T19:17:51Z2016ROSÁRIO, Mateus Santana do et al. Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report. American Journal of Tropical Medicine and Hygiene, v. 95, n. 5, p. 1157-1160, Nov. 2016. DOI: https://doi.org/10.4269/ajtmh.16-0306. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094232/pdf/tropmed-95-1157.pdf.1476-1645https://patua.iec.gov.br/handle/iec/246810.4269/ajtmh.16-0306Zika virus (ZIKV) is an emerging flavivirus, which has caused a widespread outbreak in the Americas. Shortly after its introduction in 2015, a cluster of cases with Guillain-Barré syndrome was detected in Brazil. Herein, we describe two cases from the city of Salvador, who developed ascending paresis after an acute exanthematous illness. The patients were admitted to the intensive care unit with tetraparesis and cranial nerve palsy, which resolved after intravenous administration of human immunoglobulin. Serological evaluation detected IgM-specific ZIKV antibodies. In regions of Zika virus transmission, health-care workers must be aware of the potential severe neurological complications associated with ZIKV infection and be prepared to provide prompt diagnosis, treatment, and supportive care.Secretaria Estadual da Saúde da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brazil.Secretaria Estadual da Saúde da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brazil.University of Texas Medical Branch. Institute for Human Infections and Immunity. Department of Pathology. Center for Biodefense and Emerging Infectious Diseases. Galveston, TX, Texas / University of Texas Medical Branch. Center for Tropical Diseases. Galveston, TX, Texas.Secretaria Estadual da Saúde da Bahia. Hospital Geral Roberto Santos. Salvador, BA, Brazil.Fundação Monte Tabor. Hospital São Rafael. Salvador, BA, Brazil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Ananindeua, PA, Brasil.Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, Connecticut.Ministério da Saúde. Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brazil.Ministério da Saúde. Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brazil.application/pdfengAmerican Society of Tropical Medicine and HygieneGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case reportSíndrome de Guillain-Barré após Infecção por vírus Zika no Brasil: relato de casoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleInfecção pelo Zika virus / diagnósticoInfecção pelo Zika virus / complicaçõesSíndrome de Guillain-Barré / complicaçõesDoenças do Sistema Nervoso / complicaçõesTestes de Inibição da Hemaglutinação / métodosEnsaio de Imunoadsorção Enzimática / métodosReação em Cadeia da Polimerase Via Transcriptase Reversa / métodosBrasil / epidemiologiainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case report.pdfGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case report.pdfapplication/pdf456842https://patua.iec.gov.br/bitstreams/8930e86d-a663-48f1-a8ea-5141c41331f5/download253e0fec0c2aa36e249a02141bd613d6MD52TEXTGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case report.pdf.txtGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case report.pdf.txtExtracted texttext/plain22480https://patua.iec.gov.br/bitstreams/e4cf7be3-1feb-4197-8585-957592d5000e/download28991c13be13e371b19515af2166970dMD56THUMBNAILGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case report.pdf.jpgGuillain–Barré Syndrome after Zika Virus Infection in Brazil: case report.pdf.jpgGenerated Thumbnailimage/jpeg5934https://patua.iec.gov.br/bitstreams/1fc4a4de-8c1d-4724-bf59-5dd16a8f6e8b/downloadfab2a8f19a8650be7a4e03302f6c2e1fMD57LICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
dc.title.alternative.pt_BR.fl_str_mv Síndrome de Guillain-Barré após Infecção por vírus Zika no Brasil: relato de caso
title Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
spellingShingle Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
Rosário, Mateus Santana do
Infecção pelo Zika virus / diagnóstico
Infecção pelo Zika virus / complicações
Síndrome de Guillain-Barré / complicações
Doenças do Sistema Nervoso / complicações
Testes de Inibição da Hemaglutinação / métodos
Ensaio de Imunoadsorção Enzimática / métodos
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Brasil / epidemiologia
title_short Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
title_full Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
title_fullStr Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
title_full_unstemmed Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
title_sort Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report
author Rosário, Mateus Santana do
author_facet Rosário, Mateus Santana do
Jesus, Pedro Antonio Pereira de
Vasilakis, Nikos
Farias, Daniel Santana
Novaes, Marco Antônio Caires
Rodrigues, Sueli Guerreiro
Martins, Lívia Caricio
Vasconcelos, Pedro Fernando da Costa
Ko, Albert Icksang
Alcantara, Luiz Carlos Júnior
Siqueira, Isadora Cristina de
author_role author
author2 Jesus, Pedro Antonio Pereira de
Vasilakis, Nikos
Farias, Daniel Santana
Novaes, Marco Antônio Caires
Rodrigues, Sueli Guerreiro
Martins, Lívia Caricio
Vasconcelos, Pedro Fernando da Costa
Ko, Albert Icksang
Alcantara, Luiz Carlos Júnior
Siqueira, Isadora Cristina de
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rosário, Mateus Santana do
Jesus, Pedro Antonio Pereira de
Vasilakis, Nikos
Farias, Daniel Santana
Novaes, Marco Antônio Caires
Rodrigues, Sueli Guerreiro
Martins, Lívia Caricio
Vasconcelos, Pedro Fernando da Costa
Ko, Albert Icksang
Alcantara, Luiz Carlos Júnior
Siqueira, Isadora Cristina de
dc.subject.decsPrimary.pt_BR.fl_str_mv Infecção pelo Zika virus / diagnóstico
Infecção pelo Zika virus / complicações
Síndrome de Guillain-Barré / complicações
Doenças do Sistema Nervoso / complicações
Testes de Inibição da Hemaglutinação / métodos
Ensaio de Imunoadsorção Enzimática / métodos
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Brasil / epidemiologia
topic Infecção pelo Zika virus / diagnóstico
Infecção pelo Zika virus / complicações
Síndrome de Guillain-Barré / complicações
Doenças do Sistema Nervoso / complicações
Testes de Inibição da Hemaglutinação / métodos
Ensaio de Imunoadsorção Enzimática / métodos
Reação em Cadeia da Polimerase Via Transcriptase Reversa / métodos
Brasil / epidemiologia
description Zika virus (ZIKV) is an emerging flavivirus, which has caused a widespread outbreak in the Americas. Shortly after its introduction in 2015, a cluster of cases with Guillain-Barré syndrome was detected in Brazil. Herein, we describe two cases from the city of Salvador, who developed ascending paresis after an acute exanthematous illness. The patients were admitted to the intensive care unit with tetraparesis and cranial nerve palsy, which resolved after intravenous administration of human immunoglobulin. Serological evaluation detected IgM-specific ZIKV antibodies. In regions of Zika virus transmission, health-care workers must be aware of the potential severe neurological complications associated with ZIKV infection and be prepared to provide prompt diagnosis, treatment, and supportive care.
publishDate 2016
dc.date.issued.fl_str_mv 2016
dc.date.accessioned.fl_str_mv 2017-02-01T19:17:51Z
dc.date.available.fl_str_mv 2017-02-01T19:17:51Z
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dc.identifier.citation.fl_str_mv ROSÁRIO, Mateus Santana do et al. Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report. American Journal of Tropical Medicine and Hygiene, v. 95, n. 5, p. 1157-1160, Nov. 2016. DOI: https://doi.org/10.4269/ajtmh.16-0306. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094232/pdf/tropmed-95-1157.pdf.
dc.identifier.uri.fl_str_mv https://patua.iec.gov.br/handle/iec/2468
dc.identifier.issn.-.fl_str_mv 1476-1645
dc.identifier.doi.pt_BR.fl_str_mv 10.4269/ajtmh.16-0306
identifier_str_mv ROSÁRIO, Mateus Santana do et al. Guillain–Barré Syndrome after Zika Virus Infection in Brazil: case report. American Journal of Tropical Medicine and Hygiene, v. 95, n. 5, p. 1157-1160, Nov. 2016. DOI: https://doi.org/10.4269/ajtmh.16-0306. Disponível em: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5094232/pdf/tropmed-95-1157.pdf.
1476-1645
10.4269/ajtmh.16-0306
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