Sequential serological surveys in the early stages of the coronavirus disease epidemic: limitations and perspectives

• Autor(a) principal: Vieira, Marcelo Adriano da Cunha e Silva
• Data de Publicação: 2020
• Outros Autores: Vieira, Chrystiany Plácido de Brito, Borba, Amaríles de Souza, Melo, Maria Clara de Carvalho, Oliveira, Marilene de Sousa, Melo, Rodrigo Moraes, Nunes, Vanessa Veloso, Santana, Wesllany Sousa, Aguiar, Yara Amorim de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Digital do Instituto Evandro Chagas (Patuá)
• Texto Completo: https://patua.iec.gov.br/handle/iec/4120
• topic: Coronavirus / patogenicidade; Infecções por Coronavirus / patogenicidade; Vírus da SARS / patogenicidade; Testes Sorológicos / estatística & dados numéricos; Imunidade Coletiva; Pandemias / história; Programas de Rastreamento; Covid - 19; Síndrome Respiratória Aguda Grave

Introduction: Estimates of the number of individuals infected by severe acute respiratory syndrome coronavirus 2 are important for health planning and establishment of expectations regarding herd immunity. Methods: Seven testing rounds of a serological survey were conducted at 1-week intervals between April 19 and May 31, 2020 in Teresina municipality. Results: Over the 7 weeks, serological positivity increased from 0.56% (95% confidence interval [CI]: 0.18%–1.30%) to 8.33% (95% CI: 6.61%–10.33%), representing 33–53 persons infected for each reported case. Conclusions: Serological screening may be an important tool for understanding the immunity of a population and planning community interventions.