Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
| Texto Completo: | https://patua.iec.gov.br/handle/iec/6720 |
Resumo: | Background: The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil. Methods: Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status. Results: None of the study sites had significantly higher POC-ECO accuracy than KK. Conclusions: POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs. |
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Pieri, Otavio SarmentoBezerra, Fernando Schemelzer MoraesCoelho, Paulo Marcos ZechEnk, Martin JohannesFavre, Tereza CristinaGraeff-Teixeira, CarlosOliveira, Ricardo RiccioReis, Mitermayer Galvão dosAndrade, Lee Senhorinha de AlmeidaBeck, Lilian Christina Nóbrega HolsbachFavero, VivianFialho, Thainá Rodrigues de SouzaGuimarães, Ricardo José de Paula Souza eOliveira, Bruna Souza SantosPascoal, Vanessa FeyPinheiro, Marta Cristhiany CunhaSantos, Ronald Alves dosSilva, Luciano KalabricSiqueira, Isadora Cristina deSouza, Renata Perotto deKatz, Naftale2023-03-07T13:42:32Z2023-03-07T13:42:32Z2023PIERI, Otavio Sarmento et al. Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study. Revista da Sociedade Brasileira de Medicina Tropical, v. 55, e0238-2022, p. 1 - 5, 2023. DOI: https://doi.org/10.1590/0037-8682-0238-2022. Disponível em: https://www.scielo.br/j/rsbmt/a/hJDms3GBtfcVP6nSLTyMXVS/?format=pdf&lang=en1678-9849https://patua.iec.gov.br/handle/iec/672010.1590/0037-8682-0238-2-22Background: The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil. Methods: Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status. Results: None of the study sites had significantly higher POC-ECO accuracy than KK. Conclusions: POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs.Secretaria de Vigilância em Saúde / Fundo Nacional de Saúde / Ministério da Saúde - [TED/FNS: 118/2017; SIAFI: 691919 / 25000.479741/2017-05Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil.Universidade Federal do Ceará. Departamento de Análises Clínicas e Toxicológicas. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Ministério da Saúde. Secretaria de Ciência, Tecnologia, Inovação e Insumos Estratégicos. Instituto Evandro Chagas. Laboratório de Parasitoses Intestinais, Esquistossomose e Malacologia. Ananindeua, PA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil.Universidade Federal do Espírito Santo. Centro de Ciências da Saúde. Unidade de Doenças Infecciosas. Vitória, ES, Brasil / Pontifícia Universidade Católica do Rio Grande do Sul. Laboratório de Parasitologia Biomédica. Porto Alegre, RS, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Yale University. School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CT, USA.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil.Pontifícia Universidade Católica do Rio Grande do Sul. Laboratório de Parasitologia Biomédica. Porto Alegre, RS, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Ministério da Saúde. Secretaria de Ciência, Tecnologia, Inovação e Insumos Estratégicos. Instituto Evandro Chagas. Laboratório de Parasitoses Intestinais, Esquistossomose e Malacologia. Ananindeua, PA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Pontifícia Universidade Católica do Rio Grande do Sul. Laboratório de Parasitologia Biomédica. Porto Alegre, RS, Brasil.Universidade Federal do Ceará. Departamento de Análises Clínicas e Toxicológicas. Fortaleza, CE, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Pontifícia Universidade Católica do Rio Grande do Sul. Laboratório de Parasitologia Biomédica. Porto Alegre, RS, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.engSociedade Brasileira de Medicina TropicalAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter studyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSchistosoma mansoni / patogenicidadeTestes ImediatosEsquistossomose mansoni / urinaTestes LaboratoriaisKato-KatzHelmintex®info:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study.pdfAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study.pdfapplication/pdf1302699https://patua.iec.gov.br/bitstreams/361dab1e-ea62-450a-bab2-642f13202ed5/download9fa321a9a0009328934cc08c4cb2e82dMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/4591befd-7139-4ce3-a207-3ce9dd450df0/download11832eea31b16df8613079d742d61793MD52TEXTAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study.pdf.txtAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study.pdf.txtExtracted texttext/plain27881https://patua.iec.gov.br/bitstreams/722d64f2-b754-4d31-ae6c-cb973081c59b/download3ac84680afc6ce55d405279a26a26442MD53THUMBNAILAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study.pdf.jpgAccuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study.pdf.jpgGenerated Thumbnailimage/jpeg7020https://patua.iec.gov.br/bitstreams/9e769585-2ce1-4dc5-91b3-e9c2483f4bf0/download0fb3addf3a055a468490db20066d0262MD54iec/67202023-03-07 16:55:20.458oai:patua.iec.gov.br:iec/6720https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2023-03-07T16:55:20Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)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 |
| dc.title.pt_BR.fl_str_mv |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| title |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| spellingShingle |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study Pieri, Otavio Sarmento Schistosoma mansoni / patogenicidade Testes Imediatos Esquistossomose mansoni / urina Testes Laboratoriais Kato-Katz Helmintex® |
| title_short |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| title_full |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| title_fullStr |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| title_full_unstemmed |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| title_sort |
Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study |
| author |
Pieri, Otavio Sarmento |
| author_facet |
Pieri, Otavio Sarmento Bezerra, Fernando Schemelzer Moraes Coelho, Paulo Marcos Zech Enk, Martin Johannes Favre, Tereza Cristina Graeff-Teixeira, Carlos Oliveira, Ricardo Riccio Reis, Mitermayer Galvão dos Andrade, Lee Senhorinha de Almeida Beck, Lilian Christina Nóbrega Holsbach Favero, Vivian Fialho, Thainá Rodrigues de Souza Guimarães, Ricardo José de Paula Souza e Oliveira, Bruna Souza Santos Pascoal, Vanessa Fey Pinheiro, Marta Cristhiany Cunha Santos, Ronald Alves dos Silva, Luciano Kalabric Siqueira, Isadora Cristina de Souza, Renata Perotto de Katz, Naftale |
| author_role |
author |
| author2 |
Bezerra, Fernando Schemelzer Moraes Coelho, Paulo Marcos Zech Enk, Martin Johannes Favre, Tereza Cristina Graeff-Teixeira, Carlos Oliveira, Ricardo Riccio Reis, Mitermayer Galvão dos Andrade, Lee Senhorinha de Almeida Beck, Lilian Christina Nóbrega Holsbach Favero, Vivian Fialho, Thainá Rodrigues de Souza Guimarães, Ricardo José de Paula Souza e Oliveira, Bruna Souza Santos Pascoal, Vanessa Fey Pinheiro, Marta Cristhiany Cunha Santos, Ronald Alves dos Silva, Luciano Kalabric Siqueira, Isadora Cristina de Souza, Renata Perotto de Katz, Naftale |
| author2_role |
author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Pieri, Otavio Sarmento Bezerra, Fernando Schemelzer Moraes Coelho, Paulo Marcos Zech Enk, Martin Johannes Favre, Tereza Cristina Graeff-Teixeira, Carlos Oliveira, Ricardo Riccio Reis, Mitermayer Galvão dos Andrade, Lee Senhorinha de Almeida Beck, Lilian Christina Nóbrega Holsbach Favero, Vivian Fialho, Thainá Rodrigues de Souza Guimarães, Ricardo José de Paula Souza e Oliveira, Bruna Souza Santos Pascoal, Vanessa Fey Pinheiro, Marta Cristhiany Cunha Santos, Ronald Alves dos Silva, Luciano Kalabric Siqueira, Isadora Cristina de Souza, Renata Perotto de Katz, Naftale |
| dc.subject.decsPrimary.pt_BR.fl_str_mv |
Schistosoma mansoni / patogenicidade Testes Imediatos Esquistossomose mansoni / urina Testes Laboratoriais Kato-Katz Helmintex® |
| topic |
Schistosoma mansoni / patogenicidade Testes Imediatos Esquistossomose mansoni / urina Testes Laboratoriais Kato-Katz Helmintex® |
| description |
Background: The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil. Methods: Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status. Results: None of the study sites had significantly higher POC-ECO accuracy than KK. Conclusions: POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs. |
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2023 |
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2023-03-07T13:42:32Z |
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2023-03-07T13:42:32Z |
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2023 |
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PIERI, Otavio Sarmento et al. Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study. Revista da Sociedade Brasileira de Medicina Tropical, v. 55, e0238-2022, p. 1 - 5, 2023. DOI: https://doi.org/10.1590/0037-8682-0238-2022. Disponível em: https://www.scielo.br/j/rsbmt/a/hJDms3GBtfcVP6nSLTyMXVS/?format=pdf&lang=en |
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https://patua.iec.gov.br/handle/iec/6720 |
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1678-9849 |
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10.1590/0037-8682-0238-2-22 |
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PIERI, Otavio Sarmento et al. Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: a multicenter study. Revista da Sociedade Brasileira de Medicina Tropical, v. 55, e0238-2022, p. 1 - 5, 2023. DOI: https://doi.org/10.1590/0037-8682-0238-2022. Disponível em: https://www.scielo.br/j/rsbmt/a/hJDms3GBtfcVP6nSLTyMXVS/?format=pdf&lang=en 1678-9849 10.1590/0037-8682-0238-2-22 |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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