Rotavirus serotype G9 Is associated with more-severe disease in Latin America
Autor(a) principal: | |
---|---|
Data de Publicação: | 2006 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Digital do Instituto Evandro Chagas (Patuá) |
Texto Completo: | https://patua.iec.gov.br/handle/iec/1074 |
Resumo: | The association between rotavirus serotypes and severity is not well established. Analysis of a clinical trial conducted in Latin America points at more-severe disease associated with serotype G9. Thus, demonstration of efficacy against G9 will be an important asset of any rotavirus vaccine to be introduced into a Latin American country or any country where G9 has been shown to be prevalent. |
id |
IEC-2_b4f3f2664b77fb656940e66d975d049e |
---|---|
oai_identifier_str |
oai:patua.iec.gov.br:iec/1074 |
network_acronym_str |
IEC-2 |
network_name_str |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
repository_id_str |
|
spelling |
Linhares, Alexandre da CostaVerstraeten, ThomasWolleswinkel-van den Bosch, JudithClemens, RalfBreuer, Thomas2016-01-26T11:43:44Z2016-01-26T11:43:44Z2006LINHARES, Alexandre da Costa et al. Rotavirus serotype G9 Is associated with more-severe disease in Latin America. Clinical Infectious Diseases, v. 43, n. 3, p. 312-314, Aug. 20061058-4838https://patua.iec.gov.br/handle/iec/1074The association between rotavirus serotypes and severity is not well established. Analysis of a clinical trial conducted in Latin America points at more-severe disease associated with serotype G9. Thus, demonstration of efficacy against G9 will be an important asset of any rotavirus vaccine to be introduced into a Latin American country or any country where G9 has been shown to be prevalent.Ministério da Saúde. Secretaria de Vigilância em Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.GlaxoSmithKline Biologicals. Rixensart, Belgium.Pallas Health Research and Consultancy. Rotterdam.GlaxoSmithKline Biologicals. Rio de Janeiro, RJ, Brasil.GlaxoSmithKline Biologicals. Rixensart, Belgium.application/pdfengOxford University PressRotavirus serotype G9 Is associated with more-severe disease in Latin Americainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRotavirus / classificaçãoInfecções por Rotavirus / epidemiologiaGastroenteriteVacinas contra Rotavirus / uso terapêuticoAmérica Latinainfo:eu-repo/semantics/openAccessreponame:Repositório Digital do Instituto Evandro Chagas (Patuá)instname:Instituto Evandro Chagas (IEC)instacron:IECORIGINALRotavirus serotype G9 Is associated with more-severe disease in Latin America .pdfapplication/pdf73054https://patua.iec.gov.br/bitstreams/d6e03ca9-931d-4d82-9460-e23ffaa220fb/download7495bc04b651c47fd8f70724a6a20616MD51TEXTfile_1.pdf.txtfile_1.pdf.txtExtracted texttext/plain12978https://patua.iec.gov.br/bitstreams/1adb508f-98cd-48d0-aff9-515b86212969/downloadd36b6e3ce75af46387bf484004f9539dMD52Rotavirus serotype G9 Is associated with more-severe disease in Latin America .pdf.txtRotavirus serotype G9 Is associated with more-severe disease in Latin America .pdf.txtExtracted texttext/plain13164https://patua.iec.gov.br/bitstreams/af177985-8201-4f59-b0ce-2790598d0382/downloadeff54f9958bb41b356e0946173a66811MD56THUMBNAILRotavirus serotype G9 Is associated with more-severe disease in Latin America .pdf.jpgRotavirus serotype G9 Is associated with more-severe disease in Latin America .pdf.jpgGenerated Thumbnailimage/jpeg6069https://patua.iec.gov.br/bitstreams/aaafafd0-ccc9-4d81-ba5b-0bef529e8c3a/download64b2d16271790e3b1ab4bc9bc61b0ed2MD57LICENSElicense.txtlicense.txttext/plain; charset=utf-82182https://patua.iec.gov.br/bitstreams/d70298a4-abf8-4277-b3b0-41f89707970a/download11832eea31b16df8613079d742d61793MD55iec/10742022-10-20 21:07:59.377oai:patua.iec.gov.br:iec/1074https://patua.iec.gov.brRepositório InstitucionalPUBhttps://patua.iec.gov.br/oai/requestclariceneta@iec.gov.br || Biblioteca@iec.gov.bropendoar:2022-10-20T21:07:59Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC)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 |
dc.title.pt_BR.fl_str_mv |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
title |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
spellingShingle |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America Linhares, Alexandre da Costa Rotavirus / classificação Infecções por Rotavirus / epidemiologia Gastroenterite Vacinas contra Rotavirus / uso terapêutico América Latina |
title_short |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
title_full |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
title_fullStr |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
title_full_unstemmed |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
title_sort |
Rotavirus serotype G9 Is associated with more-severe disease in Latin America |
author |
Linhares, Alexandre da Costa |
author_facet |
Linhares, Alexandre da Costa Verstraeten, Thomas Wolleswinkel-van den Bosch, Judith Clemens, Ralf Breuer, Thomas |
author_role |
author |
author2 |
Verstraeten, Thomas Wolleswinkel-van den Bosch, Judith Clemens, Ralf Breuer, Thomas |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Linhares, Alexandre da Costa Verstraeten, Thomas Wolleswinkel-van den Bosch, Judith Clemens, Ralf Breuer, Thomas |
dc.subject.decsPrimary.pt_BR.fl_str_mv |
Rotavirus / classificação Infecções por Rotavirus / epidemiologia Gastroenterite Vacinas contra Rotavirus / uso terapêutico América Latina |
topic |
Rotavirus / classificação Infecções por Rotavirus / epidemiologia Gastroenterite Vacinas contra Rotavirus / uso terapêutico América Latina |
description |
The association between rotavirus serotypes and severity is not well established. Analysis of a clinical trial conducted in Latin America points at more-severe disease associated with serotype G9. Thus, demonstration of efficacy against G9 will be an important asset of any rotavirus vaccine to be introduced into a Latin American country or any country where G9 has been shown to be prevalent. |
publishDate |
2006 |
dc.date.issued.fl_str_mv |
2006 |
dc.date.accessioned.fl_str_mv |
2016-01-26T11:43:44Z |
dc.date.available.fl_str_mv |
2016-01-26T11:43:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
LINHARES, Alexandre da Costa et al. Rotavirus serotype G9 Is associated with more-severe disease in Latin America. Clinical Infectious Diseases, v. 43, n. 3, p. 312-314, Aug. 2006 |
dc.identifier.uri.fl_str_mv |
https://patua.iec.gov.br/handle/iec/1074 |
dc.identifier.issn.-.fl_str_mv |
1058-4838 |
identifier_str_mv |
LINHARES, Alexandre da Costa et al. Rotavirus serotype G9 Is associated with more-severe disease in Latin America. Clinical Infectious Diseases, v. 43, n. 3, p. 312-314, Aug. 2006 1058-4838 |
url |
https://patua.iec.gov.br/handle/iec/1074 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Oxford University Press |
publisher.none.fl_str_mv |
Oxford University Press |
dc.source.none.fl_str_mv |
reponame:Repositório Digital do Instituto Evandro Chagas (Patuá) instname:Instituto Evandro Chagas (IEC) instacron:IEC |
instname_str |
Instituto Evandro Chagas (IEC) |
instacron_str |
IEC |
institution |
IEC |
reponame_str |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
collection |
Repositório Digital do Instituto Evandro Chagas (Patuá) |
bitstream.url.fl_str_mv |
https://patua.iec.gov.br/bitstreams/d6e03ca9-931d-4d82-9460-e23ffaa220fb/download https://patua.iec.gov.br/bitstreams/1adb508f-98cd-48d0-aff9-515b86212969/download https://patua.iec.gov.br/bitstreams/af177985-8201-4f59-b0ce-2790598d0382/download https://patua.iec.gov.br/bitstreams/aaafafd0-ccc9-4d81-ba5b-0bef529e8c3a/download https://patua.iec.gov.br/bitstreams/d70298a4-abf8-4277-b3b0-41f89707970a/download |
bitstream.checksum.fl_str_mv |
7495bc04b651c47fd8f70724a6a20616 d36b6e3ce75af46387bf484004f9539d eff54f9958bb41b356e0946173a66811 64b2d16271790e3b1ab4bc9bc61b0ed2 11832eea31b16df8613079d742d61793 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Digital do Instituto Evandro Chagas (Patuá) - Instituto Evandro Chagas (IEC) |
repository.mail.fl_str_mv |
clariceneta@iec.gov.br || Biblioteca@iec.gov.br |
_version_ |
1787533055223660544 |